Detalhe da pesquisa
1.
A Novel and Fast Online-SPE-LC-MS/MS Method to Quantify Thyroid Hormone Metabolites in Rat Plasma.
Chem Res Toxicol
; 37(1): 33-41, 2024 01 15.
Artigo
Inglês
| MEDLINE | ID: mdl-38078760
2.
Towards a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny - Part IV: the ECETOC and CLE Proposal for a Thyroid Function-Related Neurodevelopmental Toxicity Testing and Assessment Scheme (Thyroid-NDT-TAS).
Crit Rev Toxicol
; 53(6): 339-371, 2023 07.
Artigo
Inglês
| MEDLINE | ID: mdl-37554099
3.
Boscalid shows increased thyroxin-glucuronidation in rat but not in human hepatocytes in vitro.
J Appl Toxicol
; 43(6): 828-844, 2023 06.
Artigo
Inglês
| MEDLINE | ID: mdl-36549901
4.
Towards a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny-part III: how is substance-mediated thyroid hormone imbalance in pregnant/lactating rats or their progeny related to neurodevelopmental effects?
Crit Rev Toxicol
; 52(7): 546-617, 2022 08.
Artigo
Inglês
| MEDLINE | ID: mdl-36519295
5.
Towards a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny - part II: how can key events of relevant adverse outcome pathways be addressed in toxicological assessments?
Crit Rev Toxicol
; 51(4): 328-358, 2021 04.
Artigo
Inglês
| MEDLINE | ID: mdl-34074207
6.
A review of species differences in the control of, and response to, chemical-induced thyroid hormone perturbations leading to thyroid cancer.
Arch Toxicol
; 95(3): 807-836, 2021 03.
Artigo
Inglês
| MEDLINE | ID: mdl-33398420
7.
Toward a science-based testing strategy to identify maternal thyroid hormone imbalance and neurodevelopmental effects in the progeny - part I: which parameters from human studies are most relevant for toxicological assessments?
Crit Rev Toxicol
; 50(9): 740-763, 2020 10.
Artigo
Inglês
| MEDLINE | ID: mdl-33305658
8.
The Cumulative Risk Assessment of Hepatotoxic Chemicals: A Hepatic Histopathology Perspective.
Toxicol Pathol
; 48(3): 397-410, 2020 04.
Artigo
Inglês
| MEDLINE | ID: mdl-31933429
9.
Adversity Considerations for Thyroid Follicular Cell Hypertrophy and Hyperplasia in Nonclinical Toxicity Studies: Results From the 6th ESTP International Expert Workshop.
Toxicol Pathol
; 48(8): 920-938, 2020 12.
Artigo
Inglês
| MEDLINE | ID: mdl-33334259
10.
A flow scheme for cumulative assessment of pesticides for adverse liver effects.
Regul Toxicol Pharmacol
; 116: 104694, 2020 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-32621977
11.
A comprehensive view on mechanistic approaches for cancer risk assessment of non-genotoxic agrochemicals.
Regul Toxicol Pharmacol
; 118: 104789, 2020 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-33035627
12.
Investigations on the dose-response relationship of combined exposure to low doses of three anti-androgens in Wistar rats.
Arch Toxicol
; 91(12): 3961-3989, 2017 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-28879601
13.
Comparing effect levels of regulatory studies with endpoints derived in targeted anti-androgenic studies: example prochloraz.
Arch Toxicol
; 91(1): 143-162, 2017 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-26914364
14.
Investigations of putative reproductive toxicity of low-dose exposures to vinclozolin in Wistar rats.
Arch Toxicol
; 91(4): 1941-1956, 2017 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-27612472
15.
Investigations of putative reproductive toxicity of low-dose exposures to flutamide in Wistar rats.
Arch Toxicol
; 89(12): 2385-402, 2015 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-26525394
16.
Anti-androgenicity can only be evaluated using a weight of evidence approach.
Regul Toxicol Pharmacol
; 68(1): 175-92, 2014 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-24184466
17.
Effect of estrogenic binary mixtures in the yeast estrogen screen (YES).
Regul Toxicol Pharmacol
; 70(1): 286-96, 2014 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-25017362
18.
Thyroid Hormone Metabolites Quantified in Pup and Adult Rat Cerebellum, Cortex and Whole-Brain Samples Using an Automated Online SPE-LC-MS/MS Method.
Metabolites
; 14(1)2024 Jan 17.
Artigo
Inglês
| MEDLINE | ID: mdl-38248864
19.
The grouping of chemicals with effects on reproduction and development for the purpose of cumulative risk assessment in Europe.
Reprod Toxicol
; 109: 39-52, 2022 04.
Artigo
Inglês
| MEDLINE | ID: mdl-35219832
20.
Assessment of combinations of antiandrogenic compounds vinclozolin and flutamide in a yeast based reporter assay.
Regul Toxicol Pharmacol
; 60(3): 373-80, 2011 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-21620918