Detalhe da pesquisa
1.
Mesoscale DNA feature in antibody-coding sequence facilitates somatic hypermutation.
Cell
; 186(10): 2193-2207.e19, 2023 05 11.
Artigo
Inglês
| MEDLINE | ID: mdl-37098343
2.
A di-acetyl-decorated chromatin signature couples liquid condensation to suppress DNA end synapsis.
Mol Cell
; 84(7): 1206-1223.e15, 2024 Apr 04.
Artigo
Inglês
| MEDLINE | ID: mdl-38423014
3.
Chromosomal Loop Domains Direct the Recombination of Antigen Receptor Genes.
Cell
; 163(4): 947-59, 2015 Nov 05.
Artigo
Inglês
| MEDLINE | ID: mdl-26593423
4.
Sequence-Intrinsic Mechanisms that Target AID Mutational Outcomes on Antibody Genes.
Cell
; 163(5): 1124-1137, 2015 Nov 19.
Artigo
Inglês
| MEDLINE | ID: mdl-26582132
5.
Convergent transcription at intragenic super-enhancers targets AID-initiated genomic instability.
Cell
; 159(7): 1538-48, 2014 Dec 18.
Artigo
Inglês
| MEDLINE | ID: mdl-25483776
6.
Taming AID mutator activity in somatic hypermutation.
Trends Biochem Sci
; 2024 Apr 12.
Artigo
Inglês
| MEDLINE | ID: mdl-38614818
7.
Mechanisms of programmed DNA lesions and genomic instability in the immune system.
Cell
; 152(3): 417-29, 2013 Jan 31.
Artigo
Inglês
| MEDLINE | ID: mdl-23374339
8.
DNA flexibility can shape the preferential hypermutation of antibody genes.
Trends Immunol
; 45(3): 167-176, 2024 03.
Artigo
Inglês
| MEDLINE | ID: mdl-38402044
9.
C-terminal deletion-induced condensation sequesters AID from IgH targets in immunodeficiency.
EMBO J
; 41(11): e109324, 2022 06 01.
Artigo
Inglês
| MEDLINE | ID: mdl-35471583
10.
The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substrates.
Cell
; 144(3): 353-63, 2011 Feb 04.
Artigo
Inglês
| MEDLINE | ID: mdl-21255825
11.
Deafness-associated tRNAPhe mutation impaired mitochondrial and cellular integrity.
J Biol Chem
; 300(5): 107235, 2024 Mar 27.
Artigo
Inglês
| MEDLINE | ID: mdl-38552739
12.
AID Recognizes Structured DNA for Class Switch Recombination.
Mol Cell
; 67(3): 361-373.e4, 2017 Aug 03.
Artigo
Inglês
| MEDLINE | ID: mdl-28757211
13.
Ig Enhancers Increase RNA Polymerase II Stalling at Somatic Hypermutation Target Sequences.
J Immunol
; 208(1): 143-154, 2022 01 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34862258
14.
Small-molecule activators specific to adenine base editors through blocking the canonical TGF-ß pathway.
Nucleic Acids Res
; 50(17): 9632-9646, 2022 09 23.
Artigo
Inglês
| MEDLINE | ID: mdl-36043443
15.
A deafness-associated mitochondrial DNA mutation caused pleiotropic effects on DNA replication and tRNA metabolism.
Nucleic Acids Res
; 50(16): 9453-9469, 2022 09 09.
Artigo
Inglês
| MEDLINE | ID: mdl-36039763
16.
Human TRUB1 is a highly conserved pseudouridine synthase responsible for the formation of Ψ55 in mitochondrial tRNAAsn, tRNAGln, tRNAGlu and tRNAPro.
Nucleic Acids Res
; 50(16): 9368-9381, 2022 09 09.
Artigo
Inglês
| MEDLINE | ID: mdl-36018806
17.
Comparison of NOD-like and Toll-like receptors gene expression levels in blood monocytes of colon cancer patients.
Cell Mol Biol (Noisy-le-grand)
; 69(15): 103-107, 2023 Dec 31.
Artigo
Inglês
| MEDLINE | ID: mdl-38279478
18.
Phosphatidylinositol 3-kinase δ blockade increases genomic instability in B cells.
Nature
; 542(7642): 489-493, 2017 02 23.
Artigo
Inglês
| MEDLINE | ID: mdl-28199309
19.
Global detection of DNA repair outcomes induced by CRISPR-Cas9.
Nucleic Acids Res
; 49(15): 8732-8742, 2021 09 07.
Artigo
Inglês
| MEDLINE | ID: mdl-34365511
20.
A deafness-associated tRNA mutation caused pleiotropic effects on the m1G37 modification, processing, stability and aminoacylation of tRNAIle and mitochondrial translation.
Nucleic Acids Res
; 49(2): 1075-1093, 2021 01 25.
Artigo
Inglês
| MEDLINE | ID: mdl-33398350