Detalhe da pesquisa
1.
Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex.
Cell
; 171(2): 414-426.e12, 2017 Oct 05.
Artigo
Inglês
| MEDLINE | ID: mdl-28985564
2.
Cryo-EM Structures of the Magnesium Channel CorA Reveal Symmetry Break upon Gating.
Cell
; 164(4): 747-56, 2016 Feb 11.
Artigo
Inglês
| MEDLINE | ID: mdl-26871634
3.
Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery.
Cell
; 165(7): 1698-1707, 2016 Jun 16.
Artigo
Inglês
| MEDLINE | ID: mdl-27238019
4.
Destabilizing NF1 variants act in a dominant negative manner through neurofibromin dimerization.
Proc Natl Acad Sci U S A
; 120(5): e2208960120, 2023 Jan 31.
Artigo
Inglês
| MEDLINE | ID: mdl-36689660
5.
Structural basis of kainate subtype glutamate receptor desensitization.
Nature
; 537(7621): 567-571, 2016 Sep 22.
Artigo
Inglês
| MEDLINE | ID: mdl-27580033
6.
Accounting for the Ewald Spheres in CryoEM Reconstructions and Their Relationship to 3D Fourier Transforms of Focal Series.
Microsc Microanal
; 29(Supplement_1): 1030-1031, 2023 Jul 22.
Artigo
Inglês
| MEDLINE | ID: mdl-37613436
7.
Structure of ß-galactosidase at 3.2-Å resolution obtained by cryo-electron microscopy.
Proc Natl Acad Sci U S A
; 111(32): 11709-14, 2014 Aug 12.
Artigo
Inglês
| MEDLINE | ID: mdl-25071206
8.
Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.
Mol Pharmacol
; 89(6): 645-51, 2016 06.
Artigo
Inglês
| MEDLINE | ID: mdl-27036132
9.
Cryo-EM Analysis of the Conformational Landscape of Human P-glycoprotein (ABCB1) During its Catalytic Cycle.
Mol Pharmacol
; 90(1): 35-41, 2016 07.
Artigo
Inglês
| MEDLINE | ID: mdl-27190212
10.
A molecular mechanism for the generation of ligand-dependent differential outputs by the epidermal growth factor receptor.
Elife
; 102021 11 30.
Artigo
Inglês
| MEDLINE | ID: mdl-34846302
11.
Malaria parasites use a soluble RhopH complex for erythrocyte invasion and an integral form for nutrient uptake.
Elife
; 102021 01 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33393463
12.
1.8 Å resolution structure of ß-galactosidase with a 200â kV CRYO ARM electron microscope.
IUCrJ
; 7(Pt 4): 639-643, 2020 Jul 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32695410
13.
Cryo-EM structures reveal coordinated domain motions that govern DNA cleavage by Cas9.
Nat Struct Mol Biol
; 26(8): 679-685, 2019 08.
Artigo
Inglês
| MEDLINE | ID: mdl-31285607
14.
Cryo-EM structure of a dimeric B-Raf:14-3-3 complex reveals asymmetry in the active sites of B-Raf kinases.
Science
; 366(6461): 109-115, 2019 10 04.
Artigo
Inglês
| MEDLINE | ID: mdl-31604311
15.
2.3 Å resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition.
Science
; 351(6275): 871-5, 2016 Feb 19.
Artigo
Inglês
| MEDLINE | ID: mdl-26822609
16.
2.2 Å resolution cryo-EM structure of ß-galactosidase in complex with a cell-permeant inhibitor.
Science
; 348(6239): 1147-51, 2015 Jun 05.
Artigo
Inglês
| MEDLINE | ID: mdl-25953817
17.
HIV-1 envelope glycoprotein structure.
Curr Opin Struct Biol
; 23(2): 268-76, 2013 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-23602427
18.
Prefusion structure of trimeric HIV-1 envelope glycoprotein determined by cryo-electron microscopy.
Nat Struct Mol Biol
; 20(12): 1352-7, 2013 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-24154805