Detalhe da pesquisa
1.
Recent advances in dopamine D2 receptor ligands in the treatment of neuropsychiatric disorders.
Med Res Rev
; 43(1): 55-211, 2023 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36111795
2.
Huprine Y - Tryptophan heterodimers with potential implication to Alzheimer's disease treatment.
Bioorg Med Chem Lett
; 43: 128100, 2021 07 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33984470
3.
Recent advances with 5-HT3 modulators for neuropsychiatric and gastrointestinal disorders.
Med Res Rev
; 40(5): 1593-1678, 2020 09.
Artigo
Inglês
| MEDLINE | ID: mdl-32115745
4.
From orexin receptor agonist YNT-185 to novel antagonists with drug-like properties for the treatment of insomnia.
Bioorg Chem
; 103: 104179, 2020 10.
Artigo
Inglês
| MEDLINE | ID: mdl-32891860
5.
Synthesis, in vitro screening and molecular docking of isoquinolinium-5-carbaldoximes as acetylcholinesterase and butyrylcholinesterase reactivators.
J Enzyme Inhib Med Chem
; 35(1): 478-488, 2020 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-31910701
6.
Orexin supplementation in narcolepsy treatment: A review.
Med Res Rev
; 39(3): 961-975, 2019 05.
Artigo
Inglês
| MEDLINE | ID: mdl-30426515
7.
Profiling donepezil template into multipotent hybrids with antioxidant properties.
J Enzyme Inhib Med Chem
; 33(1): 583-606, 2018 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-29529892
8.
Investigation of New Orexin 2 Receptor Modulators Using In Silico and In Vitro Methods.
Molecules
; 23(11)2018 Nov 09.
Artigo
Inglês
| MEDLINE | ID: mdl-30423961
9.
Novel Tacrine-Scutellarin Hybrids as Multipotent Anti-Alzheimer's Agents: Design, Synthesis and Biological Evaluation.
Molecules
; 22(6)2017 Jun 16.
Artigo
Inglês
| MEDLINE | ID: mdl-28621747
10.
Development of 2-Methoxyhuprine as Novel Lead for Alzheimer's Disease Therapy.
Molecules
; 22(8)2017 Jul 28.
Artigo
Inglês
| MEDLINE | ID: mdl-28788095
11.
7-Methoxytacrine-p-Anisidine Hybrids as Novel Dual Binding Site Acetylcholinesterase Inhibitors for Alzheimer's Disease Treatment.
Molecules
; 20(12): 22084-101, 2015 Dec 10.
Artigo
Inglês
| MEDLINE | ID: mdl-26690394
12.
Morphing cholinesterase inhibitor amiridine into multipotent drugs for the treatment of Alzheimer's disease.
Biomed Pharmacother
; 173: 116399, 2024 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-38492439
13.
2,6-Disubstituted 7-(naphthalen-2-ylmethyl)-7H-purines as a new class of potent antitubercular agents inhibiting DprE1.
Eur J Med Chem
; 258: 115611, 2023 Oct 05.
Artigo
Inglês
| MEDLINE | ID: mdl-37421887
14.
Non-covalent acetylcholinesterase inhibitors: In vitro screening and molecular modeling for novel selective insecticides.
Toxicol In Vitro
; 85: 105463, 2022 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-36041654
15.
Novel D2/5-HT receptor modulators related to cariprazine with potential implication to schizophrenia treatment.
Eur J Med Chem
; 232: 114193, 2022 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-35176563
16.
Jaspine B Hydrochloride-induced Apoptosis in HeLa Cells Is Associated With Disrupted Sphingolipid Metabolism and Ceramide Overload.
Anticancer Res
; 41(6): 2875-2883, 2021 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-34083278
17.
Synthesis and In Vitro Evaluation of Novel Dopamine Receptor D2 3,4-dihydroquinolin-2(1H)-one Derivatives Related to Aripiprazole.
Biomolecules
; 11(9)2021 08 24.
Artigo
Inglês
| MEDLINE | ID: mdl-34572475
18.
2-Propargylamino-naphthoquinone derivatives as multipotent agents for the treatment of Alzheimer's disease.
Eur J Med Chem
; 211: 113112, 2021 Feb 05.
Artigo
Inglês
| MEDLINE | ID: mdl-33360800
19.
Phenothiazine-Tacrine Heterodimers: Pursuing Multitarget Directed Approach in Alzheimer's Disease.
ACS Chem Neurosci
; 12(9): 1698-1715, 2021 05 05.
Artigo
Inglês
| MEDLINE | ID: mdl-33852284
20.
Discovery of multifunctional anti-Alzheimer's agents with a unique mechanism of action including inhibition of the enzyme butyrylcholinesterase and γ-aminobutyric acid transporters.
Eur J Med Chem
; 218: 113397, 2021 Jun 05.
Artigo
Inglês
| MEDLINE | ID: mdl-33838585