Detalhe da pesquisa
1.
A randomized, double-blind, placebo-controlled phase 2 study to assess safety, tolerability, and efficacy of RT001 in patients with amyotrophic lateral sclerosis.
Eur J Neurol
; 30(12): 3722-3731, 2023 12.
Artigo
Inglês
| MEDLINE | ID: mdl-37550954
2.
An expanded access protocol of RT001 in amyotrophic lateral sclerosis-Initial experience with a lipid peroxidation inhibitor.
Muscle Nerve
; 66(4): 421-425, 2022 10.
Artigo
Inglês
| MEDLINE | ID: mdl-35765222
3.
Double blind trial of a deuterated form of linoleic acid (RT001) in Friedreich ataxia.
J Neurol
; 270(3): 1615-1623, 2023 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-36462055
4.
Electrophysiological and ECG Effects of Perhexiline, a Mixed Cardiac Ion Channel Inhibitor, Evaluated in Nonclinical Assays and in Healthy Subjects.
J Clin Pharmacol
; 61(12): 1606-1617, 2021 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34214210
5.
RT001 in Progressive Supranuclear Palsy-Clinical and In-Vitro Observations.
Antioxidants (Basel)
; 10(7)2021 Jun 25.
Artigo
Inglês
| MEDLINE | ID: mdl-34202031
6.
Randomized comparison of everolimus-eluting and paclitaxel-eluting stents: two-year clinical follow-up from the Clinical Evaluation of the Xience V Everolimus Eluting Coronary Stent System in the Treatment of Patients with de novo Native Coronary Artery Lesions (SPIRIT) III trial.
Circulation
; 119(5): 680-6, 2009 Feb 10.
Artigo
Inglês
| MEDLINE | ID: mdl-19171853
7.
The infantile neuroaxonal dystrophy rating scale (INAD-RS).
Orphanet J Rare Dis
; 15(1): 195, 2020 07 29.
Artigo
Inglês
| MEDLINE | ID: mdl-32727524
8.
Plasma and Red Blood Cell Membrane Accretion and Pharmacokinetics of RT001 (bis-Allylic 11,11-D2-Linoleic Acid Ethyl Ester) during Long Term Dosing in Patients.
J Pharm Sci
; 109(11): 3496-3503, 2020 11.
Artigo
Inglês
| MEDLINE | ID: mdl-32871154
9.
Treatment of infantile neuroaxonal dystrophy with RT001: A di-deuterated ethyl ester of linoleic acid: Report of two cases.
JIMD Rep
; 54(1): 54-60, 2020 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-32685351
10.
The natural history of infantile neuroaxonal dystrophy.
Orphanet J Rare Dis
; 15(1): 109, 2020 05 01.
Artigo
Inglês
| MEDLINE | ID: mdl-32357911
11.
Gender-based evaluation of the XIENCE V everolimus-eluting coronary stent system: clinical and angiographic results from the SPIRIT III randomized trial.
Catheter Cardiovasc Interv
; 74(5): 719-27, 2009 Nov 01.
Artigo
Inglês
| MEDLINE | ID: mdl-19530147
12.
Comparison of an everolimus-eluting stent and a paclitaxel-eluting stent in patients with coronary artery disease: a randomized trial.
JAMA
; 299(16): 1903-13, 2008 Apr 23.
Artigo
Inglês
| MEDLINE | ID: mdl-18430909
13.
Clinical outcomes comparing eptifibatide and abciximab in ST elevation acute myocardial infarction patients undergoing percutaneous coronary interventions.
Cardiology
; 107(3): 172-7, 2007.
Artigo
Inglês
| MEDLINE | ID: mdl-16940721
14.
The validation of an LC-MS/MS assay for perhexiline and major hydroxy metabolites, and its application to therapeutic monitoring in patient plasma.
Bioanalysis
; 9(13): 1011-1025, 2017 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-28692346
15.
Pharmacokinetics and pharmacodynamics of tecarfarin, a novel vitamin K antagonist oral anticoagulant.
Thromb Haemost
; 117(4): 706-717, 2017 04 03.
Artigo
Inglês
| MEDLINE | ID: mdl-28180234
16.
Pharmacokinetics of Tecarfarin and Warfarin in Patients with Severe Chronic Kidney Disease.
Thromb Haemost
; 117(11): 2026-2033, 2017 11.
Artigo
Inglês
| MEDLINE | ID: mdl-28933798
17.
Gender-based outcomes after paclitaxel-eluting stent implantation in patients with coronary artery disease.
J Am Coll Cardiol
; 45(8): 1180-5, 2005 Apr 19.
Artigo
Inglês
| MEDLINE | ID: mdl-15837246
18.
A randomised, double blind comparison of tecarfarin, a novel vitamin K antagonist, with warfarin. The EmbraceAC Trial.
Thromb Haemost
; 116(2): 241-50, 2016 08 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27173100
19.
Analysis of 1-year clinical outcomes in the SIRIUS trial: a randomized trial of a sirolimus-eluting stent versus a standard stent in patients at high risk for coronary restenosis.
Circulation
; 109(5): 634-40, 2004 Feb 10.
Artigo
Inglês
| MEDLINE | ID: mdl-14769686
20.
Non-polymer-based paclitaxel-coated coronary stents for the treatment of patients with de novo coronary lesions: angiographic follow-up of the DELIVER clinical trial.
Circulation
; 109(16): 1948-54, 2004 Apr 27.
Artigo
Inglês
| MEDLINE | ID: mdl-15078794