Detalhe da pesquisa
1.
SORL1 is a receptor for tau that promotes tau seeding.
J Biol Chem
; : 107313, 2024 Apr 22.
Artigo
Inglês
| MEDLINE | ID: mdl-38657864
2.
Regulation of tau internalization, degradation, and seeding by LRP1 reveals multiple pathways for tau catabolism.
J Biol Chem
; 296: 100715, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-33930462
3.
High-affinity binding of plasminogen-activator inhibitor 1 complexes to LDL receptor-related protein 1 requires lysines 80, 88, and 207.
J Biol Chem
; 295(1): 212-222, 2020 01 03.
Artigo
Inglês
| MEDLINE | ID: mdl-31792055
4.
High-Affinity Binding of LDL Receptor-Related Protein 1 to Matrix Metalloprotease 1 Requires Protease:Inhibitor Complex Formation.
Biochemistry
; 59(32): 2922-2933, 2020 08 18.
Artigo
Inglês
| MEDLINE | ID: mdl-32702237
5.
LRP1 (Low-Density Lipoprotein Receptor-Related Protein 1) Regulates Smooth Muscle Contractility by Modulating Ca2+ Signaling and Expression of Cytoskeleton-Related Proteins.
Arterioscler Thromb Vasc Biol
; 38(11): 2651-2664, 2018 11.
Artigo
Inglês
| MEDLINE | ID: mdl-30354243
6.
Macrophage LRP1 Promotes Diet-Induced Hepatic Inflammation and Metabolic Dysfunction by Modulating Wnt Signaling.
Mediators Inflamm
; 2018: 7902841, 2018.
Artigo
Inglês
| MEDLINE | ID: mdl-30524198
7.
Evidence That Factor VIII Forms a Bivalent Complex with the Low Density Lipoprotein (LDL) Receptor-related Protein 1 (LRP1): IDENTIFICATION OF CLUSTER IV ON LRP1 AS THE MAJOR BINDING SITE.
J Biol Chem
; 291(50): 26035-26044, 2016 Dec 09.
Artigo
Inglês
| MEDLINE | ID: mdl-27794518
8.
Regulation of Itch and Nedd4 E3 Ligase Activity and Degradation by LRAD3.
Biochemistry
; 55(8): 1204-13, 2016 Mar 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26854353
9.
Generation of a Potent Low Density Lipoprotein Receptor-related Protein 1 (LRP1) Antagonist by Engineering a Stable Form of the Receptor-associated Protein (RAP) D3 Domain.
J Biol Chem
; 290(28): 17262-8, 2015 Jul 10.
Artigo
Inglês
| MEDLINE | ID: mdl-26013822
10.
Mac-1 Regulates IL-13 Activity in Macrophages by Directly Interacting with IL-13Rα1.
J Biol Chem
; 290(35): 21642-51, 2015 Aug 28.
Artigo
Inglês
| MEDLINE | ID: mdl-26160172
11.
LRP1 protects the vasculature by regulating levels of connective tissue growth factor and HtrA1.
Arterioscler Thromb Vasc Biol
; 33(9): 2137-46, 2013 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-23868935
12.
LRP1 protects against excessive superior mesenteric artery remodeling by modulating angiotensin II-mediated signaling.
JCI Insight
; 8(2)2023 Jan 24.
Artigo
Inglês
| MEDLINE | ID: mdl-36472907
13.
LRAD3, a novel low-density lipoprotein receptor family member that modulates amyloid precursor protein trafficking.
J Neurosci
; 31(30): 10836-46, 2011 Jul 27.
Artigo
Inglês
| MEDLINE | ID: mdl-21795536
14.
Characterization of interaction between blood coagulation factor VIII and LRP1 suggests dynamic binding by alternating complex contacts.
J Thromb Haemost
; 20(10): 2255-2269, 2022 10.
Artigo
Inglês
| MEDLINE | ID: mdl-35810466
15.
Low density lipoprotein receptor-related protein 1 (LRP1) forms a signaling complex with platelet-derived growth factor receptor-beta in endosomes and regulates activation of the MAPK pathway.
J Biol Chem
; 285(19): 14308-17, 2010 May 07.
Artigo
Inglês
| MEDLINE | ID: mdl-20220145
16.
Midkine drives cardiac inflammation by promoting neutrophil trafficking and NETosis in myocarditis.
J Exp Med
; 216(2): 350-368, 2019 02 04.
Artigo
Inglês
| MEDLINE | ID: mdl-30647120
17.
LDL Receptor-Related Protein-1 (LRP1) Regulates Cholesterol Accumulation in Macrophages.
PLoS One
; 10(6): e0128903, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-26061292
18.
Development of human serine protease-based therapeutics targeting Fn14 and identification of Fn14 as a new target overexpressed in TNBC.
Mol Cancer Ther
; 13(11): 2688-705, 2014 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-25239934
19.
The LDL receptor-related protein 1 (LRP1) regulates the PDGF signaling pathway by binding the protein phosphatase SHP-2 and modulating SHP-2- mediated PDGF signaling events.
PLoS One
; 8(7): e70432, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-23922991
20.
Macrophage LRP1 suppresses neo-intima formation during vascular remodeling by modulating the TGF-ß signaling pathway.
PLoS One
; 6(12): e28846, 2011.
Artigo
Inglês
| MEDLINE | ID: mdl-22174911