Detalhe da pesquisa
1.
An anti-peptide monoclonal antibody recognizing the tobacco etch virus protease-cleavage sequence and its application to a tandem tagging system.
Protein Expr Purif
; 147: 94-99, 2018 07.
Artigo
Inglês
| MEDLINE | ID: mdl-29550370
2.
Structural basis for semaphorin signalling through the plexin receptor.
Nature
; 467(7319): 1123-7, 2010 Oct 28.
Artigo
Inglês
| MEDLINE | ID: mdl-20881961
3.
Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling.
Proc Natl Acad Sci U S A
; 109(42): 16876-81, 2012 Oct 16.
Artigo
Inglês
| MEDLINE | ID: mdl-23027977
4.
Locally misfolded HER2 expressed on cancer cells is a promising target for development of cancer-specific antibodies.
Structure
; 32(5): 536-549.e5, 2024 May 02.
Artigo
Inglês
| MEDLINE | ID: mdl-38460519
5.
Designing receptor agonists with enhanced pharmacokinetics by grafting macrocyclic peptides into fragment crystallizable regions.
Nat Biomed Eng
; 7(2): 164-176, 2023 02.
Artigo
Inglês
| MEDLINE | ID: mdl-36344661
6.
Expression, purification, crystallization and preliminary X-ray crystallographic analysis of Enpp1.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 68(Pt 7): 778-82, 2012 Jul 01.
Artigo
Inglês
| MEDLINE | ID: mdl-22750863
7.
Functional role of the Frizzled linker domain in the Wnt signaling pathway.
Commun Biol
; 5(1): 421, 2022 05 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35513706
8.
Hybrid in vitro/in silico analysis of low-affinity protein-protein interactions that regulate signal transduction by Sema6D.
Protein Sci
; 31(11): e4452, 2022 11.
Artigo
Inglês
| MEDLINE | ID: mdl-36156831
9.
Selective targeting of multiple myeloma cells with a monoclonal antibody recognizing the ubiquitous protein CD98 heavy chain.
Sci Transl Med
; 14(632): eaax7706, 2022 02 16.
Artigo
Inglês
| MEDLINE | ID: mdl-35171652
10.
De novo peptide grafting to a self-assembling nanocapsule yields a hepatocyte growth factor receptor agonist.
iScience
; 24(11): 103302, 2021 Nov 19.
Artigo
Inglês
| MEDLINE | ID: mdl-34805784
11.
Structural mechanism of laminin recognition by integrin.
Nat Commun
; 12(1): 4012, 2021 06 29.
Artigo
Inglês
| MEDLINE | ID: mdl-34188035
12.
Lasso-grafting of macrocyclic peptide pharmacophores yields multi-functional proteins.
Nat Commun
; 12(1): 1543, 2021 03 09.
Artigo
Inglês
| MEDLINE | ID: mdl-33750839
13.
Engineered ACE2 receptor therapy overcomes mutational escape of SARS-CoV-2.
Nat Commun
; 12(1): 3802, 2021 06 21.
Artigo
Inglês
| MEDLINE | ID: mdl-34155214
14.
Macrocyclic peptides that inhibit Wnt signalling via interaction with Wnt3a.
RSC Chem Biol
; 1(1): 26-34, 2020 Apr 16.
Artigo
Inglês
| MEDLINE | ID: mdl-34458746
15.
Crystal structure of a mammalian Wnt-frizzled complex.
Nat Struct Mol Biol
; 26(5): 372-379, 2019 05.
Artigo
Inglês
| MEDLINE | ID: mdl-31036956
16.
Structure and mechanism of cancer-associated N-acetylglucosaminyltransferase-V.
Nat Commun
; 9(1): 3380, 2018 08 23.
Artigo
Inglês
| MEDLINE | ID: mdl-30140003
17.
Immunoaffinity Purification of the Glycosylated Extracellular Fragment of Mouse Plexin A2 Produced in a Mammalian Expression System.
Methods Mol Biol
; 1493: 57-72, 2017.
Artigo
Inglês
| MEDLINE | ID: mdl-27787842
18.
Conformational Freedom of the LRP6 Ectodomain Is Regulated by N-glycosylation and the Binding of the Wnt Antagonist Dkk1.
Cell Rep
; 18(1): 32-40, 2017 01 03.
Artigo
Inglês
| MEDLINE | ID: mdl-28052259
19.
Mechanistic insights into ectodomain shedding: susceptibility of CADM1 adhesion molecule is determined by alternative splicing and O-glycosylation.
Sci Rep
; 7: 46174, 2017 04 10.
Artigo
Inglês
| MEDLINE | ID: mdl-28393893
20.
Active and water-soluble form of lipidated Wnt protein is maintained by a serum glycoprotein afamin/α-albumin.
Elife
; 52016 Feb 23.
Artigo
Inglês
| MEDLINE | ID: mdl-26902720