Detalhe da pesquisa
1.
Genomics of Alzheimer's disease implicates the innate and adaptive immune systems.
Cell Mol Life Sci
; 78(23): 7397-7426, 2021 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-34708251
2.
Correction: Abeta targets of the biosimilar antibodies of Bapineuzumab, Crenezumab, Solanezumab in comparison to an antibody against N-truncted Abeta in sporadic Alzheimer disease cases and mouse models.
Acta Neuropathol
; 147(1): 59, 2024 Mar 25.
Artigo
Inglês
| MEDLINE | ID: mdl-38526686
3.
Promiscuous DNA-binding of a mutant zinc finger protein corrupts the transcriptome and diminishes cell viability.
Nucleic Acids Res
; 45(3): 1130-1143, 2017 02 17.
Artigo
Inglês
| MEDLINE | ID: mdl-28180284
4.
Abeta targets of the biosimilar antibodies of Bapineuzumab, Crenezumab, Solanezumab in comparison to an antibody against Ntruncated Abeta in sporadic Alzheimer disease cases and mouse models.
Acta Neuropathol
; 130(5): 713-29, 2015 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-26467270
5.
Do current therapeutic anti-Aß antibodies for Alzheimer's disease engage the target?
Acta Neuropathol
; 127(6): 803-10, 2014.
Artigo
Inglês
| MEDLINE | ID: mdl-24803227
6.
Pre-targeting amyloid-ß with antibodies for potential molecular imaging of Alzheimer's disease.
Chem Commun (Camb)
; 59(16): 2243-2246, 2023 Feb 21.
Artigo
Inglês
| MEDLINE | ID: mdl-36723107
7.
Associations of plasma soluble CD22 levels with brain amyloid burden and cognitive decline in Alzheimer's disease.
Sci Adv
; 8(13): eabm5667, 2022 04.
Artigo
Inglês
| MEDLINE | ID: mdl-35363517
8.
Anti-Aß antibody target engagement: a response to Siemers et al.
Acta Neuropathol
; 128(4): 611-4, 2014 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-25120193
9.
Small Molecule Binding to Alzheimer Risk Factor CD33 Promotes Aß Phagocytosis.
iScience
; 19: 110-118, 2019 Sep 27.
Artigo
Inglês
| MEDLINE | ID: mdl-31369984
10.
Cu2+ binding modes of recombinant alpha-synuclein--insights from EPR spectroscopy.
J Am Chem Soc
; 130(24): 7766-73, 2008 Jun 18.
Artigo
Inglês
| MEDLINE | ID: mdl-18494470
11.
Crystallization and preliminary X-ray diffraction analysis of the Fab fragment of WO2, an antibody specific for the Abeta peptides associated with Alzheimer's disease.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 64(Pt 5): 438-41, 2008 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-18453721
12.
Ex vivo 18O-labeling mass spectrometry identifies a peripheral amyloid ß clearance pathway.
Mol Neurodegener
; 12(1): 18, 2017 02 20.
Artigo
Inglês
| MEDLINE | ID: mdl-28219449
13.
Transitional changes in the CRP structure lead to the exposure of proinflammatory binding sites.
Nat Commun
; 8: 14188, 2017 01 23.
Artigo
Inglês
| MEDLINE | ID: mdl-28112148
14.
Molecular basis for mid-region amyloid-ß capture by leading Alzheimer's disease immunotherapies.
Sci Rep
; 5: 9649, 2015 Apr 16.
Artigo
Inglês
| MEDLINE | ID: mdl-25880481
15.
Crystallization and preliminary X-ray diffraction analysis of the Fab portion of the Alzheimer's disease immunotherapy candidate bapineuzumab complexed with amyloid-ß.
Acta Crystallogr F Struct Biol Commun
; 70(Pt 3): 374-7, 2014 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-24598931
16.
Bapineuzumab captures the N-terminus of the Alzheimer's disease amyloid-beta peptide in a helical conformation.
Sci Rep
; 3: 1302, 2013.
Artigo
Inglês
| MEDLINE | ID: mdl-23416764
17.
Structural approaches to probing metal interaction with proteins.
J Inorg Biochem
; 115: 138-47, 2012 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-22437159
18.
An Escherichia coli cell-free system for recombinant protein synthesis on a milligram scale.
Methods Mol Biol
; 752: 17-28, 2011.
Artigo
Inglês
| MEDLINE | ID: mdl-21713628
19.
Solid-phase synthesis of homodimeric peptides: preparation of covalently-linked dimers of amyloid beta peptide.
Chem Commun (Camb)
; (41): 6228-30, 2009 Nov 07.
Artigo
Inglês
| MEDLINE | ID: mdl-19826677
20.
Copper binding to the Alzheimer's disease amyloid precursor protein.
Eur Biophys J
; 37(3): 269-79, 2008 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-18030462