Detalhe da pesquisa
1.
Predictability of B cell clonal persistence and immunosurveillance in breast cancer.
Nat Immunol
; 25(5): 916-924, 2024 May.
Artigo
Inglês
| MEDLINE | ID: mdl-38698238
2.
In vitro evolution of antibody affinity via insertional scanning mutagenesis of an entire antibody variable region.
Proc Natl Acad Sci U S A
; 117(44): 27307-27318, 2020 11 03.
Artigo
Inglês
| MEDLINE | ID: mdl-33067389
3.
Multiplexed Affinity Characterization of Protein Binders Directly from a Crude Cell Lysate by Covalent Capture on Suspension Bead Arrays.
Anal Chem
; 93(4): 2166-2173, 2021 02 02.
Artigo
Inglês
| MEDLINE | ID: mdl-33397084
4.
A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, and FcRn Binding.
J Immunol
; 198(1): 528-537, 2017 01 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27881707
5.
Phenotypic screening-the fast track to novel antibody discovery.
Drug Discov Today Technol
; 23: 83-90, 2017 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-28647091
6.
Identification of anti-tumour biologics using primary tumour models, 3-D phenotypic screening and image-based multi-parametric profiling.
Mol Cancer
; 14: 147, 2015 Jul 31.
Artigo
Inglês
| MEDLINE | ID: mdl-26227951
7.
Handicap-Recover Evolution Leads to a Chemically Versatile, Nucleophile-Permissive Protease.
Chembiochem
; 16(13): 1866-1869, 2015 Sep 07.
Artigo
Inglês
| MEDLINE | ID: mdl-26097079
8.
Correction: A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, and FcRn Binding.
J Immunol
; 199(5): 1943, 2017 09 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28827388
9.
Rapid discovery of high-affinity antibodies via massively parallel sequencing, ribosome display and affinity screening.
Nat Biomed Eng
; 8(3): 214-232, 2024 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-37814006
10.
Combining phenotypic and proteomic approaches to identify membrane targets in a 'triple negative' breast cancer cell type.
Mol Cancer
; 12: 11, 2013 Feb 13.
Artigo
Inglês
| MEDLINE | ID: mdl-23406016
11.
Gigavalent Display of Proteins on Monodisperse Polyacrylamide Hydrogels as a Versatile Modular Platform for Functional Assays and Protein Engineering.
ACS Cent Sci
; 8(8): 1182-1195, 2022 Aug 24.
Artigo
Inglês
| MEDLINE | ID: mdl-36032770
12.
Phenotypic whole-cell screening identifies a protective carbohydrate epitope on Klebsiella pneumoniae.
MAbs
; 14(1): 2006123, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-34923908
13.
A receptor for the complement regulator factor H increases transmission of trypanosomes to tsetse flies.
Nat Commun
; 11(1): 1326, 2020 03 12.
Artigo
Inglês
| MEDLINE | ID: mdl-32165615
14.
Deep Sequencing of B Cell Receptor Repertoires From COVID-19 Patients Reveals Strong Convergent Immune Signatures.
Front Immunol
; 11: 605170, 2020.
Artigo
Inglês
| MEDLINE | ID: mdl-33384691
15.
Exosomal delivery of doxorubicin enables rapid cell entry and enhanced in vitro potency.
PLoS One
; 14(3): e0214545, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-30925190
16.
Structure of the trypanosome transferrin receptor reveals mechanisms of ligand recognition and immune evasion.
Nat Microbiol
; 4(12): 2074-2081, 2019 12.
Artigo
Inglês
| MEDLINE | ID: mdl-31636418
17.
KRAS-specific inhibition using a DARPin binding to a site in the allosteric lobe.
Nat Commun
; 10(1): 2607, 2019 06 13.
Artigo
Inglês
| MEDLINE | ID: mdl-31197133
18.
A single dose of antibody-drug conjugate cures a stage 1 model of African trypanosomiasis.
PLoS Negl Trop Dis
; 13(5): e0007373, 2019 05.
Artigo
Inglês
| MEDLINE | ID: mdl-31120889
19.
In vitro DNA recombination by L-Shuffling during ribosome display affinity maturation of an anti-Fas antibody increases the population of improved variants.
Protein Eng Des Sel
; 21(5): 343-51, 2008 May.
Artigo
Inglês
| MEDLINE | ID: mdl-18411227
20.
TNFR2 ligation in human T regulatory cells enhances IL2-induced cell proliferation through the non-canonical NF-κB pathway.
Sci Rep
; 8(1): 12079, 2018 08 13.
Artigo
Inglês
| MEDLINE | ID: mdl-30104686