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1.
Trends Biochem Sci ; 2024 Jun 20.
Artigo em Inglês | MEDLINE | ID: mdl-38906726

RESUMO

A recent study by Amankwah et al. reports how co-chaperone proteins and ATP hydrolysis fine-tune the function of endoplasmic reticulum (ER)-resident Hsp90 paralog Grp94.

2.
Food Chem ; 295: 403-411, 2019 Oct 15.
Artigo em Inglês | MEDLINE | ID: mdl-31174775

RESUMO

The aim of this study was to examine the variations in sugar content and identify the polymorphism in vacuolar invertase inhibitor (INH2) gene from Indian non-processing (Kufri Jyoti, Kufri Pukhraj and PU1) and exotic processing (Atlantic and Frito Lay-1533) potato cultivars. Upon cold storage (4 °C) processing cultivars maintained low reducing sugars as compared to non-processing cultivars. Sequencing of the INH2 gene identified four alleles of which three identified as novel alleles. A total twelve SNPs resulted in silent mutations, with five conferring the amino acid substitutions. Phylogenetic analysis suggests a highly conserved nature of the INH2 gene. The 3D predicted structures generated for all the alleles revealed slight variations in the orientation of the helices (α1-3) in N-terminal region. Sequence polymorphism observed in INH2 alleles in processing and non-processing potato cultivars can be correlated with the observed variations in the sugar content suggesting a possible role in cold-induced sweetening.


Assuntos
Proteínas de Plantas/genética , Solanum tuberosum/química , Solanum tuberosum/genética , Açúcares/química , Alelos , Armazenamento de Alimentos , Filogenia , Proteínas de Plantas/química , Polimorfismo de Nucleotídeo Único
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