Detalhe da pesquisa
1.
Detection of retinal dysfunction induced by HCN channel inhibitors using multistep light stimulus and long-duration light stimulus ERG in rats.
Exp Eye Res
; 241: 109847, 2024 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-38401854
2.
Prediction of combination effect of quinidine on the pharmacokinetics of tipepidine using a physiologically based pharmacokinetic model.
Xenobiotica
; 54(3): 107-115, 2024 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-38193900
3.
Estimation of contribution of CYP2D6 to tipepidine metabolism in humans and prolongation of the half-life of tipepidine by combination use with a CYP2D6 inhibitor in chimeric mice with humanised liver.
Xenobiotica
; 53(4): 241-247, 2023 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-37305902
4.
Use of an alternating current amplifier when recording the ERG c-wave to evaluate the function of retinal pigment epithelial cells in rats.
Doc Ophthalmol
; 145(2): 147-155, 2022 10.
Artigo
Inglês
| MEDLINE | ID: mdl-35895211
5.
Applicability of the Øie-Tozer model to predict three types of distribution volume (Vd) in humans: Vd in central compartment, Vd at steady state, and Vd at beta phase.
Biopharm Drug Dispos
; 41(4-5): 151-165, 2020 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-32187715
6.
Application of zebrafish to safety evaluation in drug discovery.
J Toxicol Pathol
; 33(4): 197-210, 2020 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-33239838
7.
Abnormal axon guidance signals and reduced interhemispheric connection via anterior commissure in neonates of marmoset ASD model.
Neuroimage
; 195: 243-251, 2019 07 15.
Artigo
Inglês
| MEDLINE | ID: mdl-30953832
8.
Usefulness of Simultaneous Measurement of Plasma Steroids, Including Precursors, for the Evaluation of Drug Effects on Adrenal Steroidogenesis in Rats.
Toxicol Pathol
; 45(6): 756-763, 2017 08.
Artigo
Inglês
| MEDLINE | ID: mdl-29046138
9.
Developmental genetic profiles of glutamate receptor system, neuromodulator system, protector of normal tissue and mitochondria, and reelin in marmoset cortex: potential molecular mechanisms of pruning phase of spines in primate synaptic formation process during the end of infancy and prepuberty (II).
Biochem Biophys Res Commun
; 444(3): 307-10, 2014 Feb 14.
Artigo
Inglês
| MEDLINE | ID: mdl-24440696
10.
Developmental expression profiles of axon guidance signaling and the immune system in the marmoset cortex: potential molecular mechanisms of pruning of dendritic spines during primate synapse formation in late infancy and prepuberty (I).
Biochem Biophys Res Commun
; 444(3): 302-6, 2014 Feb 14.
Artigo
Inglês
| MEDLINE | ID: mdl-24485715
11.
Metabolic profiling of urine and blood plasma in rat models of drug addiction on the basis of morphine, methamphetamine, and cocaine-induced conditioned place preference.
Anal Bioanal Chem
; 406(5): 1339-54, 2014 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-23912828
12.
Improved seizure liability detection by combining rat hippocampal brain slice electrophysiology with in vivo behavior observation following intracerebroventricular drug administration.
J Pharmacol Toxicol Methods
; 126: 107496, 2024.
Artigo
Inglês
| MEDLINE | ID: mdl-38432527
13.
Non-invasive differentiation of hepatic steatosis and steatohepatitis in a mouse model using nitroxyl radical as an MRI-contrast agent.
Toxicol Rep
; 12: 1-9, 2024 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-38173653
14.
Altered projection-specific synaptic remodeling and its modification by oxytocin in an idiopathic autism marmoset model.
Commun Biol
; 7(1): 642, 2024 May 27.
Artigo
Inglês
| MEDLINE | ID: mdl-38802535
15.
Oral administration of drugs with hypersensitivity potential induces germinal center hyperplasia in secondary lymphoid organ/tissue in Brown Norway rats, and this histological lesion is a promising candidate as a predictive biomarker for drug hypersensitivity occurrence in humans.
Toxicol Appl Pharmacol
; 271(1): 30-40, 2013 Aug 15.
Artigo
Inglês
| MEDLINE | ID: mdl-23651737
16.
Evaluation of in vivo MRI for detecting midodrine-induced arteritis in rats.
Toxicol Rep
; 10: 97-103, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-36685272
17.
Comparison of 1H-magnetic resonance spectroscopy and blood biochemistry as methods for monitoring non-diffuse hepatic steatosis in a rat model.
Toxicol Rep
; 10: 481-486, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-37179768
18.
The effects of clobazam treatment in rats on the expression of genes and proteins encoding glucronosyltransferase 1A/2B (UGT1A/2B) and multidrug resistance-associated protein-2 (MRP2), and development of thyroid follicular cell hypertrophy.
Toxicol Appl Pharmacol
; 265(3): 351-9, 2012 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-22982618
19.
Clozapine-specific proliferative response of peripheral blood-derived mononuclear cells in Japanese patients with clozapine-induced agranulocytosis.
J Psychopharmacol
; 36(9): 1087-1094, 2022 09.
Artigo
Inglês
| MEDLINE | ID: mdl-35861221
20.
Detection of fenoldopam-induced arteritis in rats using ex vivo / in vivo MRI.
Toxicol Rep
; 9: 1595-1602, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-36518408