RESUMO
Transoral laser microsurgery (TLM) and radiotherapy (RT) are both accepted treatment modalities for glottic cancer. The objective of the study was to assess the oncologic outcomes and life quality of TLM in comparison with RT for T1 glottic carcinoma. We searched Medline/PubMed, Web of knowledge, EMBASE, the Cochrane Library, the Wiley online library, Springer, Google, China National Knowledge Infrastructure (CNKI), etc. We screened the literature, assessed the quality of the studies, and extracted the relevant data through the establishment of inclusion and exclusion criteria. Meta-analysis was done using the Cochrane collaboration' s RevMan 5.0 for data analysis. A total of 11 studies were included in this meta-analysis. The laryngeal preservation for patients undergoing TLM was significantly better than that for RT (P < 0.00). The laser surgery significantly improved the overall survival of patients with T1 glottic carcinoma (P = 0.04). No statistically significant differences were found between TLM and RT regarding the local control (P = 0.91). The funnel plot demonstrates no apparent publication bias in the overall survival and laryngeal preservation comparison. Our meta-analysis suggested that laser surgery was a preferred method than radiotherapy with respect to significantly better overall survival and laryngeal preservation. But the local control was not significant different. Further prospective randomized controlled studies will be needed.
Assuntos
Glote/patologia , Neoplasias Laríngeas/radioterapia , Neoplasias Laríngeas/cirurgia , Terapia a Laser/métodos , Microcirurgia/métodos , Neoplasias da Língua/radioterapia , Neoplasias da Língua/cirurgia , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Glote/efeitos da radiação , Humanos , Neoplasias Laríngeas/patologia , Masculino , Pessoa de Meia-Idade , Qualidade de Vida , Análise de Sobrevida , Neoplasias da Língua/patologia , Resultado do TratamentoRESUMO
We report on the vector nature of rectangular pulse operating in dissipative soliton resonance (DSR) region in a passively mode-locked fiber laser. Apart from the typical signatures of DSR, the rectangular pulse trapping of two polarization components centered at different wavelengths was observed and they propagated as a group-velocity locked vector soliton. Moreover, the polarization resolved soliton spectra show different spectral distributions. The observed results will enhance the understanding of fundamental physics of DSR phenomenon.