Detalhe da pesquisa
1.
The Structure of the Necrosome RIPK1-RIPK3 Core, a Human Hetero-Amyloid Signaling Complex.
Cell
; 173(5): 1244-1253.e10, 2018 05 17.
Artigo
Inglês
| MEDLINE | ID: mdl-29681455
2.
SARS-CoV-2 Nsp8 N-terminal domain folds autonomously and binds dsRNA.
Nucleic Acids Res
; 51(18): 10041-10048, 2023 10 13.
Artigo
Inglês
| MEDLINE | ID: mdl-37665006
3.
NMR characterization of an assembling RHIM (RIP homotypic interaction motif) amyloid reveals a cryptic region for self-recognition.
J Biol Chem
; 299(4): 104568, 2023 04.
Artigo
Inglês
| MEDLINE | ID: mdl-36870681
4.
Phe-Gly motifs drive fibrillization of TDP-43's prion-like domain condensates.
PLoS Biol
; 19(4): e3001198, 2021 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33909608
5.
Unraveling the toxic effects mediated by the neurodegenerative disease-associated S375G mutation of TDP-43 and its S375E phosphomimetic variant.
J Biol Chem
; 298(8): 102252, 2022 08.
Artigo
Inglês
| MEDLINE | ID: mdl-35835219
6.
Insight into polyproline II helical bundle stability in an antifreeze protein denatured state.
Biophys J
; 121(23): 4560-4568, 2022 12 06.
Artigo
Inglês
| MEDLINE | ID: mdl-36815707
7.
Comprehensive Fragment Screening of the SARS-CoV-2 Proteome Explores Novel Chemical Space for Drug Development.
Angew Chem Int Ed Engl
; 61(46): e202205858, 2022 11 14.
Artigo
Inglês
| MEDLINE | ID: mdl-36115062
8.
Aromatic and aliphatic residues of the disordered region of TDP-43 are on a fast track for self-assembly.
Biochem Biophys Res Commun
; 578: 110-114, 2021 11 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34560580
9.
Partial structure, dampened mobility, and modest impact of a His tag in the SARS-CoV-2 Nsp2 C-terminal region.
Eur Biophys J
; 50(8): 1129-1137, 2021 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-34633480
10.
Molecular mechanism of the inhibition of TDP-43 amyloidogenesis by QBP1.
Arch Biochem Biophys
; 675: 108113, 2019 10 30.
Artigo
Inglês
| MEDLINE | ID: mdl-31568752
11.
Point mutations in the N-terminal domain of transactive response DNA-binding protein 43 kDa (TDP-43) compromise its stability, dimerization, and functions.
J Biol Chem
; 292(28): 11992-12006, 2017 07 14.
Artigo
Inglês
| MEDLINE | ID: mdl-28566288
12.
The Singular NMR Fingerprint of a Polyproline II Helical Bundle.
J Am Chem Soc
; 140(49): 16988-17000, 2018 12 12.
Artigo
Inglês
| MEDLINE | ID: mdl-30430829
13.
Structural insight into the XTACC3/XMAP215 interaction from CD and NMR studies on model peptides.
Biopolymers
; 107(11)2017 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-28922450
15.
"Structural characterization of the minimal segment of TDP-43 competent for aggregation".
Arch Biochem Biophys
; 545: 53-62, 2014 Mar 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24440310
16.
Electrostatic Repulsion Governs TDP-43 C-terminal Domain Aggregation.
PLoS Biol
; 14(4): e1002447, 2016 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-27096426
17.
Do polyproline II helix associations modulate biomolecular condensates?
FEBS Open Bio
; 11(9): 2390-2399, 2021 09.
Artigo
Inglês
| MEDLINE | ID: mdl-33934561
18.
NMR assignments for the C-terminal domain of human TDP-43.
Biomol NMR Assign
; 15(1): 177-181, 2021 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33417141
19.
SUMOylation Regulates TDP-43 Splicing Activity and Nucleocytoplasmic Distribution.
Mol Neurobiol
; 58(11): 5682-5702, 2021 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-34390468
20.
Dysregulation of TDP-43 intracellular localization and early onset ALS are associated with a TARDBP S375G variant.
Brain Pathol
; 29(3): 397-413, 2019 05.
Artigo
Inglês
| MEDLINE | ID: mdl-30461104