Detalhe da pesquisa
1.
Probing the stochastic, motor-driven properties of the cytoplasm using force spectrum microscopy.
Cell
; 158(4): 822-832, 2014 Aug 14.
Artigo
Inglês
| MEDLINE | ID: mdl-25126787
2.
Glutamate 139 of tropomyosin is critical for cardiac thin filament blocked-state stabilization.
J Mol Cell Cardiol
; 188: 30-37, 2024 03.
Artigo
Inglês
| MEDLINE | ID: mdl-38266978
3.
M8R tropomyosin mutation disrupts actin binding and filament regulation: The beginning affects the middle and end.
J Biol Chem
; 295(50): 17128-17137, 2020 12 11.
Artigo
Inglês
| MEDLINE | ID: mdl-33020181
4.
Cardiomyopathy Mutation Alters End-to-End Junction of Tropomyosin and Reduces Calcium Sensitivity.
Biophys J
; 118(2): 303-312, 2020 01 21.
Artigo
Inglês
| MEDLINE | ID: mdl-31882250
5.
Cryo-EM and Molecular Docking Shows Myosin Loop 4 Contacts Actin and Tropomyosin on Thin Filaments.
Biophys J
; 119(4): 821-830, 2020 08 18.
Artigo
Inglês
| MEDLINE | ID: mdl-32730789
6.
A new twist on tropomyosin binding to actin filaments: perspectives on thin filament function, assembly and biomechanics.
J Muscle Res Cell Motil
; 41(1): 23-38, 2020 03.
Artigo
Inglês
| MEDLINE | ID: mdl-30771202
7.
Robust mechanobiological behavior emerges in heterogeneous myosin systems.
Proc Natl Acad Sci U S A
; 114(39): E8147-E8154, 2017 09 26.
Artigo
Inglês
| MEDLINE | ID: mdl-28900011
8.
Cell volume change through water efflux impacts cell stiffness and stem cell fate.
Proc Natl Acad Sci U S A
; 114(41): E8618-E8627, 2017 10 10.
Artigo
Inglês
| MEDLINE | ID: mdl-28973866
9.
The Effect of Tropomyosin Mutations on Actin-Tropomyosin Binding: In Search of Lost Time.
Biophys J
; 116(12): 2275-2284, 2019 06 18.
Artigo
Inglês
| MEDLINE | ID: mdl-31130236
10.
Precise Binding of Tropomyosin on Actin Involves Sequence-Dependent Variance in Coiled-Coil Twisting.
Biophys J
; 115(6): 1082-1092, 2018 09 18.
Artigo
Inglês
| MEDLINE | ID: mdl-30195938
11.
HCM and DCM cardiomyopathy-linked α-tropomyosin mutations influence off-state stability and crossbridge interaction on thin filaments.
Arch Biochem Biophys
; 647: 84-92, 2018 06 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29626422
12.
Tropomyosin Must Interact Weakly with Actin to Effectively Regulate Thin Filament Function.
Biophys J
; 113(11): 2444-2451, 2017 Dec 05.
Artigo
Inglês
| MEDLINE | ID: mdl-29211998
13.
Structural determinants of muscle thin filament cooperativity.
Arch Biochem Biophys
; 594: 8-17, 2016 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26891592
14.
Myosin regulatory light chain phosphorylation enhances cardiac ß-myosin in vitro motility under load.
Arch Biochem Biophys
; 580: 14-21, 2015 Aug 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26116789
15.
Phosphorylation of Ser283 enhances the stiffness of the tropomyosin head-to-tail overlap domain.
Arch Biochem Biophys
; 571: 10-5, 2015 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-25726728
16.
Mechanism of calponin stabilization of cross-linked actin networks.
Biophys J
; 106(4): 793-800, 2014 Feb 18.
Artigo
Inglês
| MEDLINE | ID: mdl-24559982
17.
Hypertrophic cardiomyopathy associated Lys104Glu mutation in the myosin regulatory light chain causes diastolic disturbance in mice.
J Mol Cell Cardiol
; 74: 318-29, 2014 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-24992035
18.
Tropomyosin movement on F-actin during muscle activation explained by energy landscapes.
Arch Biochem Biophys
; 545: 63-8, 2014 Mar 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24412204
19.
Energy landscapes reveal the myopathic effects of tropomyosin mutations.
Arch Biochem Biophys
; 564: 89-99, 2014 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-25241052
20.
In vitro rescue study of a malignant familial hypertrophic cardiomyopathy phenotype by pseudo-phosphorylation of myosin regulatory light chain.
Arch Biochem Biophys
; 552-553: 29-39, 2014 Jun 15.
Artigo
Inglês
| MEDLINE | ID: mdl-24374283