Detalhe da pesquisa
1.
Natural mutations in the sensor kinase of the PhoPR two-component regulatory system modulate virulence of ancestor-like tuberculosis bacilli.
PLoS Pathog
; 19(7): e1011437, 2023 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-37450466
2.
Rv0180c contributes to Mycobacterium tuberculosis cell shape and to infectivity in mice and macrophages.
PLoS Pathog
; 17(11): e1010020, 2021 11.
Artigo
Inglês
| MEDLINE | ID: mdl-34724002
3.
Host phospholipid peroxidation fuels ExoU-dependent cell necrosis and supports Pseudomonas aeruginosa-driven pathology.
PLoS Pathog
; 17(9): e1009927, 2021 09.
Artigo
Inglês
| MEDLINE | ID: mdl-34516571
4.
Long-term structural and symptomatic effects of intra-articular sprifermin in patients with knee osteoarthritis: 5-year results from the FORWARD study.
Ann Rheum Dis
; 80(8): 1062-1069, 2021 08.
Artigo
Inglês
| MEDLINE | ID: mdl-33962962
5.
Efficacy of Bedaquiline, Alone or in Combination with Imipenem, against Mycobacterium abscessus in C3HeB/FeJ Mice.
Antimicrob Agents Chemother
; 64(6)2020 05 21.
Artigo
Inglês
| MEDLINE | ID: mdl-32253217
6.
Evolutionary history of tuberculosis shaped by conserved mutations in the PhoPR virulence regulator.
Proc Natl Acad Sci U S A
; 111(31): 11491-6, 2014 Aug 05.
Artigo
Inglês
| MEDLINE | ID: mdl-25049399
7.
Multiple deletions in the polyketide synthase gene repertoire of Mycobacterium tuberculosis reveal functional overlap of cell envelope lipids in host-pathogen interactions.
Cell Microbiol
; 16(2): 195-213, 2014 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-24028583
8.
Safety, Tolerability, and Pharmacodynamics of the ADAMTS-5 Nanobody M6495: Two Phase 1, Single-Center, Double-Blind, Randomized, Placebo-Controlled Studies in Healthy Subjects and Patients With Osteoarthritis.
ACR Open Rheumatol
; 6(4): 205-213, 2024 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-38311369
9.
Enpatoran in COVID-19 pneumonia: Safety and efficacy results from a phase II randomized trial.
Clin Transl Sci
; 16(12): 2640-2653, 2023 12.
Artigo
Inglês
| MEDLINE | ID: mdl-37873555
10.
The effects of sprifermin on symptoms and structure in a subgroup at risk of progression in the FORWARD knee osteoarthritis trial.
Semin Arthritis Rheum
; 51(2): 450-456, 2021 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33752164
11.
Parallel in vivo experimental evolution reveals that increased stress resistance was key for the emergence of persistent tuberculosis bacilli.
Nat Microbiol
; 6(8): 1082-1093, 2021 08.
Artigo
Inglês
| MEDLINE | ID: mdl-34294904
12.
Pulmonary BCG induces lung-resident macrophage activation and confers long-term protection against tuberculosis.
Sci Immunol
; 6(63): eabc2934, 2021 Sep 24.
Artigo
Inglês
| MEDLINE | ID: mdl-34559551
13.
Translational strategies in drug development for knee osteoarthritis.
Drug Discov Today
; 25(6): 1054-1064, 2020 06.
Artigo
Inglês
| MEDLINE | ID: mdl-32251777
14.
Response letter to the Editor.
Semin Arthritis Rheum
; 52: 151839, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34006385
15.
The Kuvan(®) Adult Maternal Paediatric European Registry (KAMPER) Multinational Observational Study: Baseline and 1-Year Data in Phenylketonuria Patients Responsive to Sapropterin.
JIMD Rep
; 23: 35-43, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-25822821