Detalhe da pesquisa
1.
Preclinical Considerations for Long-acting Delivery of Tenofovir Alafenamide from Subdermal Implants for HIV Pre-exposure Prophylaxis.
Pharm Res
; 40(7): 1657-1672, 2023 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-36418671
2.
Safety and pharmacokinetics of single, dual, and triple antiretroviral drug formulations delivered by pod-intravaginal rings designed for HIV-1 prevention: A Phase I trial.
PLoS Med
; 15(9): e1002655, 2018 09.
Artigo
Inglês
| MEDLINE | ID: mdl-30265679
3.
Pharmacokinetics and Preliminary Safety of Pod-Intravaginal Rings Delivering the Monoclonal Antibody VRC01-N for HIV Prophylaxis in a Macaque Model.
Antimicrob Agents Chemother
; 61(7)2017 07.
Artigo
Inglês
| MEDLINE | ID: mdl-28416548
4.
Combination Pod-Intravaginal Ring Delivers Antiretroviral Agents for HIV Prophylaxis: Pharmacokinetic Evaluation in an Ovine Model.
Antimicrob Agents Chemother
; 60(6): 3759-66, 2016 06.
Artigo
Inglês
| MEDLINE | ID: mdl-27067321
5.
Pharmacokinetics of injectable, long-acting nevirapine for HIV prophylaxis in breastfeeding infants.
Antimicrob Agents Chemother
; 59(1): 59-66, 2015 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-25313219
6.
Pharmacokinetics of long-acting tenofovir alafenamide (GS-7340) subdermal implant for HIV prophylaxis.
Antimicrob Agents Chemother
; 59(7): 3913-9, 2015 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-25896688
7.
Sustained delivery of commensal bacteria from pod-intravaginal rings.
Antimicrob Agents Chemother
; 58(4): 2262-7, 2014.
Artigo
Inglês
| MEDLINE | ID: mdl-24492360
8.
Pharmacokinetics and preliminary safety study of pod-intravaginal rings delivering antiretroviral combinations for HIV prophylaxis in a macaque model.
Antimicrob Agents Chemother
; 58(9): 5125-35, 2014 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-24936594
9.
Genital epithelial barrier function is conserved by intravaginal rings releasing etonogestrel and ethinyl estradiol.
Tissue Barriers
; 12(1): 2186672, 2024 01 02.
Artigo
Inglês
| MEDLINE | ID: mdl-36899465
10.
Parenteral platforms for tunable, long-acting administration of a highly hydrophobic antiretroviral drug.
Sci Rep
; 14(1): 11573, 2024 05 21.
Artigo
Inglês
| MEDLINE | ID: mdl-38773172
11.
Pharmacokinetics of a multipurpose pod-intravaginal ring simultaneously delivering five drugs in an ovine model.
Antimicrob Agents Chemother
; 57(8): 3994-7, 2013 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-23752507
12.
Loss of genital epithelial barrier function is greater with depot-medroxyprogesterone acetate than intravaginal rings that release etonogestrel and ethinyl estradiol.
bioRxiv
; 2023 Jan 25.
Artigo
Inglês
| MEDLINE | ID: mdl-36747683
13.
Simultaneous delivery of tenofovir and acyclovir via an intravaginal ring.
Antimicrob Agents Chemother
; 56(2): 875-82, 2012 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-22123689
14.
Safety and pharmacokinetics of intravaginal rings delivering tenofovir in pig-tailed macaques.
Antimicrob Agents Chemother
; 56(11): 5952-60, 2012 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-22964245
15.
At the Crossroads of Life and Death: The Proteins That Influence Cell Fate Decisions.
Cancers (Basel)
; 14(11)2022 May 31.
Artigo
Inglês
| MEDLINE | ID: mdl-35681725
16.
Drug-releasing vaginal rings for HIV/STI and pregnancy prevention: a review of recent advances and clinical applications.
Expert Opin Drug Deliv
; 19(1): 47-58, 2022 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34958283
17.
CAPRISA 018: a phase I/II clinical trial study protocol to assess the safety, acceptability, tolerability and pharmacokinetics of a sustained-release tenofovir alafenamide subdermal implant for HIV prevention in women.
BMJ Open
; 12(1): e052880, 2022 Jan 06.
Artigo
Inglês
| MEDLINE | ID: mdl-34992111
18.
An optimized Factor H-Fc fusion protein against multidrug-resistant Neisseria gonorrhoeae.
Front Immunol
; 13: 975676, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-36110842
19.
Fundamental aspects of long-acting tenofovir alafenamide delivery from subdermal implants for HIV prophylaxis.
Sci Rep
; 12(1): 8224, 2022 05 17.
Artigo
Inglês
| MEDLINE | ID: mdl-35581262
20.
Tenofovir Alafenamide for HIV Prevention: Review of the Proceedings from the Gates Foundation Long-Acting TAF Product Development Meeting.
AIDS Res Hum Retroviruses
; 37(6): 409-420, 2021 06.
Artigo
Inglês
| MEDLINE | ID: mdl-33913760