Detalhe da pesquisa
1.
Mechanistic in vitro studies: What they have told us about carcinogenic properties of elongated mineral particles (EMPs).
Toxicol Appl Pharmacol
; 361: 62-67, 2018 12 15.
Artigo
Inglês
| MEDLINE | ID: mdl-30030095
2.
Crystalline silica alters Sulfatase-1 expression in rat lungs which influences hyper-proliferative and fibrogenic effects in human lung epithelial cells.
Toxicol Appl Pharmacol
; 348: 43-53, 2018 06 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29673857
3.
Indications for distinct pathogenic mechanisms of asbestos and silica through gene expression profiling of the response of lung epithelial cells.
Hum Mol Genet
; 24(5): 1374-89, 2015 Mar 01.
Artigo
Inglês
| MEDLINE | ID: mdl-25351596
4.
Alteration of canonical and non-canonical WNT-signaling by crystalline silica in human lung epithelial cells.
Toxicol Appl Pharmacol
; 301: 61-70, 2016 06 15.
Artigo
Inglês
| MEDLINE | ID: mdl-27095093
5.
The NLRP3 inflammasome in pathogenic particle and fibre-associated lung inflammation and diseases.
Part Fibre Toxicol
; 13(1): 51, 2016 09 20.
Artigo
Inglês
| MEDLINE | ID: mdl-27650313
6.
Extracellular signal-regulated kinase 5 and cyclic AMP response element binding protein are novel pathways inhibited by vandetanib (ZD6474) and doxorubicin in mesotheliomas.
Am J Respir Cell Mol Biol
; 51(5): 595-603, 2014 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-24940987
7.
New insights into understanding the mechanisms, pathogenesis, and management of malignant mesotheliomas.
Am J Pathol
; 182(4): 1065-77, 2013 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-23395095
8.
Asbestos modulates thioredoxin-thioredoxin interacting protein interaction to regulate inflammasome activation.
Part Fibre Toxicol
; 11: 24, 2014 May 20.
Artigo
Inglês
| MEDLINE | ID: mdl-24885895
9.
Microspheres targeted with a mesothelin antibody and loaded with doxorubicin reduce tumor volume of human mesotheliomas in xenografts.
BMC Cancer
; 13: 400, 2013 Sep 11.
Artigo
Inglês
| MEDLINE | ID: mdl-24024776
10.
Bioreactivity of the crystalline silica polymorphs, quartz and cristobalite, and implications for occupational exposure limits (OELs).
Crit Rev Toxicol
; 43(8): 632-60, 2013 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-23863112
11.
Repetitive dissociation from crocidolite asbestos acts as persistent signal for epidermal growth factor receptor.
Langmuir
; 29(21): 6323-30, 2013 May 28.
Artigo
Inglês
| MEDLINE | ID: mdl-23672436
12.
Silica induces NLRP3 inflammasome activation in human lung epithelial cells.
Part Fibre Toxicol
; 10: 3, 2013 Feb 12.
Artigo
Inglês
| MEDLINE | ID: mdl-23402370
13.
Asbestos and erionite prime and activate the NLRP3 inflammasome that stimulates autocrine cytokine release in human mesothelial cells.
Part Fibre Toxicol
; 10: 39, 2013 Aug 13.
Artigo
Inglês
| MEDLINE | ID: mdl-23937860
14.
Osteopontin modulates inflammation, mucin production, and gene expression signatures after inhalation of asbestos in a murine model of fibrosis.
Am J Pathol
; 178(5): 1975-85, 2011 May.
Artigo
Inglês
| MEDLINE | ID: mdl-21514415
15.
Differences in gene expression and cytokine production by crystalline vs. amorphous silica in human lung epithelial cells.
Part Fibre Toxicol
; 9(1): 6, 2012 Feb 02.
Artigo
Inglês
| MEDLINE | ID: mdl-22300531
16.
An extracellular signal-regulated kinase 2 survival pathway mediates resistance of human mesothelioma cells to asbestos-induced injury.
Am J Respir Cell Mol Biol
; 45(5): 906-14, 2011 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-21454801
17.
ERK2 is essential for the growth of human epithelioid malignant mesotheliomas.
Int J Cancer
; 129(5): 1075-86, 2011 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-21710492
18.
Increased efficacy of doxorubicin delivered in multifunctional microparticles for mesothelioma therapy.
Int J Cancer
; 129(1): 233-44, 2011 Jul 01.
Artigo
Inglês
| MEDLINE | ID: mdl-20830711
19.
Pulmonary endpoints (lung carcinomas and asbestosis) following inhalation exposure to asbestos.
J Toxicol Environ Health B Crit Rev
; 14(1-4): 76-121, 2011.
Artigo
Inglês
| MEDLINE | ID: mdl-21534086
20.
Myeloperoxidase deficiency attenuates lipopolysaccharide-induced acute lung inflammation and subsequent cytokine and chemokine production.
J Immunol
; 182(12): 7990-6, 2009 Jun 15.
Artigo
Inglês
| MEDLINE | ID: mdl-19494324