Detalhe da pesquisa
1.
Rational design of a new antibiotic class for drug-resistant infections.
Nature
; 597(7878): 698-702, 2021 09.
Artigo
Inglês
| MEDLINE | ID: mdl-34526714
2.
Characterization of Acinetobacter baumannii-calcoaceticus complex isolates and microbiological outcome for patients treated with sulbactam-durlobactam in a phase 3 trial (ATTACK).
Antimicrob Agents Chemother
; 68(5): e0169823, 2024 May 02.
Artigo
Inglês
| MEDLINE | ID: mdl-38567976
3.
Molecular drivers of resistance to sulbactam-durlobactam in contemporary clinical isolates of Acinetobacter baumannii.
Antimicrob Agents Chemother
; 67(11): e0066523, 2023 11 15.
Artigo
Inglês
| MEDLINE | ID: mdl-37843305
4.
In Vitro Activity of Sulbactam-Durlobactam against Acinetobacter baumannii-calcoaceticus Complex Isolates Collected Globally in 2016 and 2017.
Antimicrob Agents Chemother
; 64(4)2020 03 24.
Artigo
Inglês
| MEDLINE | ID: mdl-31988095
5.
N-Hydroxyformamide LpxC inhibitors, their in vivo efficacy in a mouse Escherichia coli infection model, and their safety in a rat hemodynamic assay.
Bioorg Med Chem
; 28(24): 115826, 2020 12 15.
Artigo
Inglês
| MEDLINE | ID: mdl-33160146
6.
Active Bax and Bak are functional holins.
Genes Dev
; 25(21): 2278-90, 2011 Nov 01.
Artigo
Inglês
| MEDLINE | ID: mdl-22006182
7.
Frequency and Mechanism of Spontaneous Resistance to Sulbactam Combined with the Novel ß-Lactamase Inhibitor ETX2514 in Clinical Isolates of Acinetobacter baumannii.
Antimicrob Agents Chemother
; 62(2)2018 02.
Artigo
Inglês
| MEDLINE | ID: mdl-29133555
8.
A synthetic lethal approach for compound and target identification in Staphylococcus aureus.
Nat Chem Biol
; 12(1): 40-5, 2016 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-26619249
9.
Compound-gene interaction mapping reveals distinct roles for Staphylococcus aureus teichoic acids.
Proc Natl Acad Sci U S A
; 111(34): 12510-5, 2014 Aug 26.
Artigo
Inglês
| MEDLINE | ID: mdl-25104751
10.
A new platform for ultra-high density Staphylococcus aureus transposon libraries.
BMC Genomics
; 16: 252, 2015 Mar 29.
Artigo
Inglês
| MEDLINE | ID: mdl-25888466
11.
Stable micron-scale holes are a general feature of canonical holins.
Mol Microbiol
; 91(1): 57-65, 2014 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-24164554
12.
Genetic dissection of T4 lysis.
J Bacteriol
; 196(12): 2201-9, 2014 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-24706740
13.
Clinical Outcomes for Patients With Monomicrobial vs Polymicrobial Acinetobacter baumannii-calcoaceticus Complex Infections Treated With Sulbactam-Durlobactam or Colistin: A Subset Analysis From a Phase 3 Clinical Trial.
Open Forum Infect Dis
; 11(4): ofae140, 2024 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-38595956
14.
In Vivo Emergence of Pandrug-Resistant Acinetobacter baumannii Strain: Comprehensive Resistance Characterization and Compassionate Use of Sulbactam-Durlobactam.
Open Forum Infect Dis
; 10(10): ofad504, 2023 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-37901122
15.
Durlobactam, a New Diazabicyclooctane ß-Lactamase Inhibitor for the Treatment of Acinetobacter Infections in Combination With Sulbactam.
Front Microbiol
; 12: 709974, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-34349751
16.
Ceftazidime-Avibactam Resistance Mutations V240G, D179Y, and D179Y/T243M in KPC-3 ß-Lactamase Do Not Alter Cefpodoxime-ETX1317 Susceptibility.
ACS Infect Dis
; 7(1): 79-87, 2021 01 08.
Artigo
Inglês
| MEDLINE | ID: mdl-33291867
17.
The Structural Basis of T4 Phage Lysis Control: DNA as the Signal for Lysis Inhibition.
J Mol Biol
; 432(16): 4623-4636, 2020 07 24.
Artigo
Inglês
| MEDLINE | ID: mdl-32562709
18.
In Vitro Characterization of ETX1317, a Broad-Spectrum ß-Lactamase Inhibitor That Restores and Enhances ß-Lactam Activity against Multi-Drug-Resistant Enterobacteriales, Including Carbapenem-Resistant Strains.
ACS Infect Dis
; 6(6): 1389-1397, 2020 06 12.
Artigo
Inglês
| MEDLINE | ID: mdl-32255609
19.
Titrating Levels of TolC in E. coli: A Sensitive Approach to Quantifying Efflux.
ACS Infect Dis
; 5(1): 49-54, 2019 01 11.
Artigo
Inglês
| MEDLINE | ID: mdl-30489063
20.
Role of the Klebsiella pneumoniae TolC porin in antibiotic efflux.
Res Microbiol
; 170(2): 112-116, 2019 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-30468763