Detalhe da pesquisa
1.
Insight into the toxic effects of cis-dichloridoplatinum(II) complexes containing 7-azaindole halogeno derivatives in tumor cells.
J Biol Inorg Chem
; 18(5): 579-89, 2013 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-23674329
2.
Antitumor bifunctional dinuclear Pt(II) complex BBR3535 forms interduplex DNA cross-links under molecular crowding conditions.
J Biol Inorg Chem
; 17(2): 239-45, 2012 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-21938443
3.
Replacement of a thiourea with an amidine group in a monofunctional platinum-acridine antitumor agent. Effect on DNA interactions, DNA adduct recognition and repair.
Mol Pharm
; 8(5): 1941-54, 2011 Oct 03.
Artigo
Inglês
| MEDLINE | ID: mdl-21806015
4.
Discovery of N2-(4-Amino-cyclohexyl)-9-cyclopentyl- N6-(4-morpholin-4-ylmethyl-phenyl)- 9H-purine-2,6-diamine as a Potent FLT3 Kinase Inhibitor for Acute Myeloid Leukemia with FLT3 Mutations.
J Med Chem
; 61(9): 3855-3869, 2018 05 10.
Artigo
Inglês
| MEDLINE | ID: mdl-29672049
5.
Anticancer potential of a photoactivated transplatin derivative containing the methylazaindole ligand mediated by ROS generation and DNA cleavage.
Dalton Trans
; 45(33): 13179-86, 2016 Aug 16.
Artigo
Inglês
| MEDLINE | ID: mdl-27396365
6.
[(η(6)-p-cymene)Ru(H2O)3](2+) binding capability of aminohydroxamates - A solution and solid state study.
J Inorg Biochem
; 160: 236-45, 2016 07.
Artigo
Inglês
| MEDLINE | ID: mdl-26971623
7.
Novel antitumor cisplatin and transplatin derivatives containing 1-methyl-7-azaindole: synthesis, characterization, and cellular responses.
J Med Chem
; 58(2): 847-59, 2015 Jan 22.
Artigo
Inglês
| MEDLINE | ID: mdl-25496325
8.
Potentiating effect of UVA irradiation on anticancer activity of Carboplatin derivatives involving 7-azaindoles.
PLoS One
; 10(4): e0123595, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-25875850
9.
Different affinity of nuclear factor-kappa B proteins to DNA modified by antitumor cisplatin and its clinically ineffective trans isomer.
FEBS J
; 281(5): 1393-1408, 2014 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-24418212
10.
How to modify 7-azaindole to form cytotoxic Pt(II) complexes: highly in vitro anticancer effective cisplatin derivatives involving halogeno-substituted 7-azaindole.
J Inorg Biochem
; 115: 57-63, 2012 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-22922312