Detalhe da pesquisa
1.
DrugMap: A quantitative pan-cancer analysis of cysteine ligandability.
Cell
; 187(10): 2536-2556.e30, 2024 May 09.
Artigo
Inglês
| MEDLINE | ID: mdl-38653237
2.
Systematic Evaluation of Bioorthogonal Reactions in Live Cells with Clickable HaloTag Ligands: Implications for Intracellular Imaging.
J Am Chem Soc
; 137(35): 11461-75, 2015 Sep 09.
Artigo
Inglês
| MEDLINE | ID: mdl-26270632
3.
Discovery of indole-derived pyridopyrazine-1,6-dione γ-secretase modulators that target presenilin.
Bioorg Med Chem Lett
; 25(4): 908-13, 2015 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-25582600
4.
γ-Secretase modulator (GSM) photoaffinity probes reveal distinct allosteric binding sites on presenilin.
J Biol Chem
; 288(14): 9710-9720, 2013 Apr 05.
Artigo
Inglês
| MEDLINE | ID: mdl-23396974
5.
DrugMap: A quantitative pan-cancer analysis of cysteine ligandability.
bioRxiv
; 2023 Oct 23.
Artigo
Inglês
| MEDLINE | ID: mdl-37961514
6.
Discovery of JNJ-64264681: A Potent and Selective Covalent Inhibitor of Bruton's Tyrosine Kinase.
J Med Chem
; 65(21): 14326-14336, 2022 11 10.
Artigo
Inglês
| MEDLINE | ID: mdl-36314537
7.
Discovery of a Potent and Selective Covalent Inhibitor of Bruton's Tyrosine Kinase with Oral Anti-Inflammatory Activity.
ACS Med Chem Lett
; 12(5): 782-790, 2021 May 13.
Artigo
Inglês
| MEDLINE | ID: mdl-34055226
8.
Identification of the plasticity-relevant fucose-alpha(1-2)-galactose proteome from the mouse olfactory bulb.
Biochemistry
; 48(30): 7261-70, 2009 Aug 04.
Artigo
Inglês
| MEDLINE | ID: mdl-19527073
9.
Development of Sulfonamide Photoaffinity Inhibitors for Probing Cellular γ-Secretase.
ACS Chem Neurosci
; 7(8): 1166-73, 2016 08 17.
Artigo
Inglês
| MEDLINE | ID: mdl-27253220
10.
The chemical neurobiology of carbohydrates.
Chem Rev
; 108(5): 1708-31, 2008 May.
Artigo
Inglês
| MEDLINE | ID: mdl-18452339
11.
Protein fucosylation regulates synapsin Ia/Ib expression and neuronal morphology in primary hippocampal neurons.
Proc Natl Acad Sci U S A
; 103(1): 21-6, 2006 Jan 03.
Artigo
Inglês
| MEDLINE | ID: mdl-16373512
12.
Oligomerization state-dependent activation of NF-kappa B signaling pathway by adipocyte complement-related protein of 30 kDa (Acrp30).
J Biol Chem
; 277(33): 29359-62, 2002 Aug 16.
Artigo
Inglês
| MEDLINE | ID: mdl-12087086
13.
Role of disulfide bonds in Acrp30/adiponectin structure and signaling specificity. Different oligomers activate different signal transduction pathways.
J Biol Chem
; 278(50): 50810-7, 2003 Dec 12.
Artigo
Inglês
| MEDLINE | ID: mdl-14522956
14.
Enhanced muscle fat oxidation and glucose transport by ACRP30 globular domain: acetyl-CoA carboxylase inhibition and AMP-activated protein kinase activation.
Proc Natl Acad Sci U S A
; 99(25): 16309-13, 2002 Dec 10.
Artigo
Inglês
| MEDLINE | ID: mdl-12456889