Detalhe da pesquisa
1.
PIM inhibitors target CD25-positive AML cells through concomitant suppression of STAT5 activation and degradation of MYC oncogene.
Blood
; 124(11): 1777-89, 2014 Sep 11.
Artigo
Inglês
| MEDLINE | ID: mdl-25006129
2.
Inhibition of pyrimidine biosynthesis targets protein translation in acute myeloid leukemia.
EMBO Mol Med
; 14(7): e15203, 2022 07 07.
Artigo
Inglês
| MEDLINE | ID: mdl-35514210
3.
Selective Vulnerability to Pyrimidine Starvation in Hematologic Malignancies Revealed by AG-636, a Novel Clinical-Stage Inhibitor of Dihydroorotate Dehydrogenase.
Mol Cancer Ther
; 19(12): 2502-2515, 2020 12.
Artigo
Inglês
| MEDLINE | ID: mdl-33082276