Detalhe da pesquisa
1.
Preclinical Drug Metabolism, Pharmacokinetic, and Pharmacodynamic Profiles of Ivosidenib, an Inhibitor of Mutant Isocitrate Dehydrogenase 1 for Treatment of Isocitrate Dehydrogenase 1-Mutant Malignancies.
Drug Metab Dispos
; 49(10): 870-881, 2021 10.
Artigo
Inglês
| MEDLINE | ID: mdl-34321251
2.
Selective CB2 receptor agonists. Part 3: the optimization of a piperidine-based series that demonstrated efficacy in an in vivo neuropathic pain model.
Bioorg Med Chem Lett
; 25(3): 587-92, 2015 Feb 01.
Artigo
Inglês
| MEDLINE | ID: mdl-25575658
3.
Selective CB2 receptor agonists. Part 2: Structure-activity relationship studies and optimization of proline-based compounds.
Bioorg Med Chem Lett
; 25(3): 581-6, 2015 Feb 01.
Artigo
Inglês
| MEDLINE | ID: mdl-25556092
4.
Population pharmacokinetics of eniporide and its metabolite in healthy subjects and patients with acute myocardial infarction.
J Clin Pharmacol
; 45(6): 631-9, 2005 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-15901744
5.
Efficacy of dichloroacetate as a lactate-lowering drug.
J Clin Pharmacol
; 43(7): 683-91, 2003 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-12856382
6.
Pharmacokinetic/pharmacodynamic modeling of luteinizing hormone (LH) suppression and LH surge delay by cetrorelix after single and multiple doses in healthy premenopausal women.
J Clin Pharmacol
; 43(3): 243-51, 2003 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-12638392
7.
Population kinetics, efficacy, and safety of dichloroacetate for lactic acidosis due to severe malaria in children.
J Clin Pharmacol
; 43(4): 386-96, 2003 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-12723459
8.
Microdialysis of triamcinolone acetonide in rat muscle.
J Pharm Sci
; 92(2): 394-7, 2003 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-12532388
9.
Evaluation of microdosing to assess pharmacokinetic linearity in rats using liquid chromatography-tandem mass spectrometry.
Drug Metab Dispos
; 34(3): 384-8, 2006 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-16326814
10.
Population pharmacokinetics of digoxin in Egyptian pediatric patients: impact of one data point utilization.
Am J Ther
; 9(6): 492-8, 2002.
Artigo
Inglês
| MEDLINE | ID: mdl-12424506