Detalhe da pesquisa
1.
LRP1 Controls TNF Release via the TIMP-3/ADAM17 Axis in Endotoxin-Activated Macrophages.
J Immunol
; 202(5): 1501-1509, 2019 03 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30659107
2.
YAP is essential for tissue tension to ensure vertebrate 3D body shape.
Nature
; 521(7551): 217-221, 2015 May 14.
Artigo
Inglês
| MEDLINE | ID: mdl-25778702
3.
Distinct biological events generated by ECM proteolysis by two homologous collagenases.
Proc Natl Acad Sci U S A
; 113(39): 10884-9, 2016 09 27.
Artigo
Inglês
| MEDLINE | ID: mdl-27630193
4.
Effects of flexibility of the α2 chain of type I collagen on collagenase cleavage.
J Struct Biol
; 203(3): 247-254, 2018 09.
Artigo
Inglês
| MEDLINE | ID: mdl-29763735
5.
Suramin Inhibits Osteoarthritic Cartilage Degradation by Increasing Extracellular Levels of Chondroprotective Tissue Inhibitor of Metalloproteinases 3.
Mol Pharmacol
; 92(4): 459-468, 2017 10.
Artigo
Inglês
| MEDLINE | ID: mdl-28798097
6.
Engineered Tissue Inhibitor of Metalloproteinases-3 Variants Resistant to Endocytosis Have Prolonged Chondroprotective Activity.
J Biol Chem
; 291(42): 22160-22172, 2016 Oct 14.
Artigo
Inglês
| MEDLINE | ID: mdl-27582494
7.
The MET/Vascular Endothelial Growth Factor Receptor (VEGFR)-targeted Tyrosine Kinase Inhibitor Also Attenuates FMS-dependent Osteoclast Differentiation and Bone Destruction Induced by Prostate Cancer.
J Biol Chem
; 291(40): 20891-20899, 2016 Sep 30.
Artigo
Inglês
| MEDLINE | ID: mdl-27539855
8.
Evidence for restricted reactivity of ADAMDEC1 with protein substrates and endogenous inhibitors.
J Biol Chem
; 290(10): 6620-9, 2015 Mar 06.
Artigo
Inglês
| MEDLINE | ID: mdl-25564618
9.
Direct Melanoma Cell Contact Induces Stromal Cell Autocrine Prostaglandin E2-EP4 Receptor Signaling That Drives Tumor Growth, Angiogenesis, and Metastasis.
J Biol Chem
; 290(50): 29781-93, 2015 Dec 11.
Artigo
Inglês
| MEDLINE | ID: mdl-26475855
10.
Anti-arthritic actions of ß-cryptoxanthin against the degradation of articular cartilage in vivo and in vitro.
Biochem Biophys Res Commun
; 476(4): 352-358, 2016 08 05.
Artigo
Inglês
| MEDLINE | ID: mdl-27240953
11.
Abrogation of prostaglandin E-EP4 signaling in osteoblasts prevents the bone destruction induced by human prostate cancer metastases.
Biochem Biophys Res Commun
; 478(1): 154-161, 2016 09 09.
Artigo
Inglês
| MEDLINE | ID: mdl-27450806
12.
BA321, a novel carborane analog that binds to androgen and estrogen receptors, acts as a new selective androgen receptor modulator of bone in male mice.
Biochem Biophys Res Commun
; 478(1): 279-285, 2016 09 09.
Artigo
Inglês
| MEDLINE | ID: mdl-27402268
13.
A personal journey with matrix metalloproteinases.
Biol Chem
; 397(9): 805-13, 2016 09 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27341559
14.
Tissue inhibitor of metalloproteinases (TIMP)-1 creates a premetastatic niche in the liver through SDF-1/CXCR4-dependent neutrophil recruitment in mice.
Hepatology
; 61(1): 238-48, 2015 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-25131778
15.
Antibody-based exosite inhibitors of ADAMTS-5 (aggrecanase-2).
Biochem J
; 471(3): 391-401, 2015 Nov 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26303525
16.
Low density lipoprotein receptor-related protein 1 (LRP1)-mediated endocytic clearance of a disintegrin and metalloproteinase with thrombospondin motifs-4 (ADAMTS-4): functional differences of non-catalytic domains of ADAMTS-4 and ADAMTS-5 in LRP1 binding.
J Biol Chem
; 289(10): 6462-6474, 2014 Mar 07.
Artigo
Inglês
| MEDLINE | ID: mdl-24474687
17.
Metalloproteinase-dependent and -independent processes contribute to inhibition of breast cancer cell migration, angiogenesis and liver metastasis by a disintegrin and metalloproteinase with thrombospondin motifs-15.
Int J Cancer
; 136(4): E14-26, 2015 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-25099234
18.
DOTAM derivatives as active cartilage-targeting drug carriers for the treatment of osteoarthritis.
Bioconjug Chem
; 26(3): 383-8, 2015 Mar 18.
Artigo
Inglês
| MEDLINE | ID: mdl-25629889
19.
Structural insights into triple-helical collagen cleavage by matrix metalloproteinase 1.
Proc Natl Acad Sci U S A
; 109(31): 12461-6, 2012 Jul 31.
Artigo
Inglês
| MEDLINE | ID: mdl-22761315
20.
Generation of a mouse line harboring a Bi-transgene expressing luciferase and tamoxifen-activatable creER(T2) recombinase in cartilage.
Genesis
; 52(2): 110-9, 2014 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-24339176