Detalhe da pesquisa
1.
A second-generation eIF4A RNA helicase inhibitor exploits translational reprogramming as a vulnerability in triple-negative breast cancer.
Proc Natl Acad Sci U S A
; 121(4): e2318093121, 2024 Jan 23.
Artigo
Inglês
| MEDLINE | ID: mdl-38232291
2.
Exploring the targeting spectrum of rocaglates among eIF4A homologs.
RNA
; 29(6): 826-835, 2023 06.
Artigo
Inglês
| MEDLINE | ID: mdl-36882295
3.
A comparative study of small molecules targeting eIF4A.
RNA
; 26(5): 541-549, 2020 05.
Artigo
Inglês
| MEDLINE | ID: mdl-32014999
4.
Identification and characterization of hippuristanol-resistant mutants reveals eIF4A1 dependencies within mRNA 5' leader regions.
Nucleic Acids Res
; 48(17): 9521-9537, 2020 09 25.
Artigo
Inglês
| MEDLINE | ID: mdl-32766783
5.
Targeting DEAD-box RNA helicases: The emergence of molecular staples.
Wiley Interdiscip Rev RNA
; 14(2): e1738, 2023 03.
Artigo
Inglês
| MEDLINE | ID: mdl-35581936
6.
C8ORF88: A Novel eIF4E-Binding Protein.
Genes (Basel)
; 14(11)2023 Nov 14.
Artigo
Inglês
| MEDLINE | ID: mdl-38003019
7.
Functional mimicry revealed by the crystal structure of an eIF4A:RNA complex bound to the interfacial inhibitor, desmethyl pateamine A.
Cell Chem Biol
; 28(6): 825-834.e6, 2021 06 17.
Artigo
Inglês
| MEDLINE | ID: mdl-33412110
8.
A forward genetic screen identifies modifiers of rocaglate responsiveness.
Sci Rep
; 11(1): 18516, 2021 09 16.
Artigo
Inglês
| MEDLINE | ID: mdl-34531456
9.
CRISPR-Based Screen Links an Inhibitor of Nonsense-Mediated Decay to eIF4A3 Target Engagement.
ACS Chem Biol
; 15(6): 1621-1629, 2020 06 19.
Artigo
Inglês
| MEDLINE | ID: mdl-32401488