Effect of pedometer-based walking on depression, anxiety and insomnia among postmenopausal women.

OBJECTIVE: Insomnia, anxiety, and depression are some psychological symptoms associated with menopause. The aim of this study was to evaluate the effect of pedometer-based walking on anxiety, insomnia, and depression among postmenopausal women. METHODS: In this randomized, controlled trial, 106 postmenopausal women were randomly assigned to two groups (n = 53 in each group). Their anxiety, insomnia, and depression levels were assessed using the GHQ-28 and Beck questionnaires in the 4th, 8th, and 12th weeks of intervention. The depression level was assessed in the beginning, and in the 12th week of the trial. The members of the intervention group each received a pedometer and were asked to increase their steps by 500 per week. Data were analyzed using the independent t-test, χ(2) and repeated-measures tests. RESULTS: The levels of anxiety and insomnia decreased in the 8th (4.2 ± 2.1 vs. 5.4 ± 2.3, p = 0.007) and 12th week (4.3 ± 2.8 vs. 7.2 ± 2.6, p < 0.001) in the intervention group, compared with the control group. The depression intensity decreased in the intervention group, compared with the control group, after 12 weeks (13.7 ± 5 vs. 19.6 ± 4.79, p < 0.001). The intervention group increased their step count from 76,377 steps per month in the first month, to 106 398 in the 3rd month (p < 0.001). CONCLUSION: This study showed that pedometer-based walking had a positive effect on depression, insomnia and anxiety among postmenopausal women. A walking training program can be considered for postmenopausal women in Iran.

Estimation of the burden of bacteriologically positive Tuberculosis among Adults in Kashmir: A baseline for future surveys in the Valley.

BACKGROUND: India has the highest burden of both Tuberculosis and MDR-Tuberculosis based on estimates reported in the Global Tuberculosis Report 2016. The estimates have been revised upwards based on the newer evidence, and the current study was done to estimate the prevalence of bacteriologically positive pulmonary Tuberculosis among the adult population and to provide baseline information for future measurements of Tuberculosis burden and trends. METHODS: A cluster-based sampling design was adopted in 10 districts of Kashmir valley in India. Assuming a prevalence of 217 per lakh population, a design effect of 2.5, a relative precision of 0.25% and the expected participation rate of 80%, a sample size of 49,716 was achieved. A total of 67 clusters were identified where each cluster had 750 subjects aged ≥15 years, and eligible individuals were questioned for pulmonary symptoms suggestive of Tuberculosis. RESULTS: Of the total 42,805 that were interviewed, 3.85% had pulmonary Tuberculosis symptoms. A total of 1539 sputum samples were collected from symptomatic and 1351 chest X- rays were done. Cartridge based nucleic acid amplification test (CBNAAT) tests were done on individuals with suspicious X-ray findings. The prevalence of bacteriologically positive pulmonary Tuberculosis was found to be 147 per 100,000 population. Females are affected more than males, and the age of female Tuberculosis patients is less than that of males. CONCLUSION: The study is the first survey of its kind providing a baseline for further research in the state. CBNAAT is going to be game-changer which surmounts the drawbacks of sputum smear microscopy.

EBIC study of electron generation function in a-Si:H.

The electron beam induced current technique was used to study electron energy loss in amorphous hydrogenated silicon a-Si:H. This study leads to the determination of the electron generation function which is needed when using the variable energy electron beam induced current technique (EBIC) analysis of a-Si:H device. A series of identical n-i-p a-Si:H diodes with a thin aluminium top electrodes were fabricated and varying thicknesses of a-Si:H layer were deposited on it. In EBIC measurements, the n-i-p diode was reverse biased at maximum potential. The electron range of a-Si:H was determined directly by measuring the energy at which the electron beam is completely stopped in the top layer and no carrier generation is possible in the n-i-p diode. The generation function is then deduced from EBIC contrast measurements between the aluminium electrode and the top a-Si:H layer.

Feasibility of intravascular ultrasound studies: predictors of imaging success before coronary interventions.

BACKGROUND: Intravascular ultrasound (IVUS) is currently used to study lesions during transcatheter coronary therapy. However, before dilation some lesions cannot be reached or crossed with the imaging catheter. HYPOTHESIS: This study seeks to elucidate which factors determine the feasibility of IVUS examination before coronary interventions. METHODS: Accordingly, 100 consecutive patients undergoing IVUS examination before coronary angioplasty were prospectively studied. The clinical and angiographic characteristics of 77 patients with a successful IVUS study (Group A) were compared with those of 23 patients in whom IVUS was attempted but the target lesion could not be interrogated (Group B). The echogenic characteristics of the target lesion [before (n = 77) or after intervention (in 18 patients in Group B)] were also studied. RESULTS: Patients in Group B were significantly older (62 +/- 7 vs. 57 +/- 10 years, p < 0.05) and more frequently had stable angina [8 (35%) vs. 9 (11%), p < 0.05]. The distribution of lesions within the coronary tree and angiographic lesion characteristics including length, eccentricity, calcification, bend location, and the American College of Cardiology/American Heart Association classification were similar in both groups. However, proximal tortuosities (> 45 degrees at end diastole) were more frequently found in Group B [20 (87%) vs. 47 (61%), p < 0.05]. In addition, by quantitative angiography, patients in Group B had smaller arteries (reference diameter 2.8 +/- 0.4 vs. 3.1 +/- 0.4 mm, p < 0.05) and more severe lesions (minimal lumen diameter 0.46 +/- 0.24 vs. 0.65 +/- 0.34 mm, p < 0.05). On IVUS, calcified lesions were more frequently visualized in Group B (61 vs. 38%, p < 0.05). On multivariate analysis, catheter size, baseline minimal lumen diameter, angiographic proximal tortuosities, and lesion calcification on imaging were independent predictors of the feasibility of IVUS studies. CONCLUSIONS: Unsuccessful IVUS studies before intervention occur more frequently (1) in vessels with proximal tortuosities or severe lumen narrowing, (2) in lesions that are calcified on IVUS, and (3) when large imaging catheters are used.

Resolución espontánea del desprendimiento macular asociado a anomalías congénitas del nervio óptico: coloboma del disco óptico y foseta papilar / Spontaneous resolution of macular detachment associated with congenital anomalies of the optic nerve: Coloboma and optic disc pit

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