Detalhe da pesquisa
1.
Cyclase-associated protein 1 is a binding partner of proprotein convertase subtilisin/kexin type-9 and is required for the degradation of low-density lipoprotein receptors by proprotein convertase subtilisin/kexin type-9.
Eur Heart J
; 41(2): 239-252, 2020 01 07.
Artigo
Inglês
| MEDLINE | ID: mdl-31419281
2.
Discovery of a Novel Triazolopyridine Derivative as a Tankyrase Inhibitor.
Int J Mol Sci
; 22(14)2021 Jul 08.
Artigo
Inglês
| MEDLINE | ID: mdl-34298950
3.
Radiosensitizing Effect of Novel Phenylpyrimidine Derivatives on Human Lung Cancer Cells via Cell Cycle Perturbation.
J Pharmacol Exp Ther
; 370(3): 514-527, 2019 09.
Artigo
Inglês
| MEDLINE | ID: mdl-31253693
4.
The small molecule AU14022 promotes colorectal cancer cell death via p53-mediated G2/M-phase arrest and mitochondria-mediated apoptosis.
J Cell Physiol
; 233(6): 4666-4676, 2018 06.
Artigo
Inglês
| MEDLINE | ID: mdl-29030986
5.
Inhibition of cancer cell invasion by new ((3,4-dihydroxy benzylidene)hydrazinyl)pyridine-3-sulfonamide analogs.
Bioorg Med Chem Lett
; 26(4): 1322-8, 2016 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26810259
6.
Identification of a Small Benzamide Inhibitor of Influenza Virus Using a Cell-Based Screening.
Chemotherapy
; 61(3): 159-66, 2016.
Artigo
Inglês
| MEDLINE | ID: mdl-26821172
7.
Discovery of 11ß-hydroxysteroid dehydrogenase type 1 inhibitor.
Bioorg Med Chem Lett
; 25(17): 3501-6, 2015 Sep 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26187704
8.
Development of cyclic peptomer inhibitors targeting the polo-box domain of polo-like kinase 1.
Bioorg Med Chem
; 21(9): 2623-34, 2013 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-23498919
9.
Identification of chalcones as potent and selective PDE5A1 inhibitors.
Bioorg Med Chem Lett
; 22(12): 3983-7, 2012 Jun 15.
Artigo
Inglês
| MEDLINE | ID: mdl-22607677
10.
Ligand aligning method for molecular docking: alignment of property-weighted vectors.
J Chem Inf Model
; 52(4): 984-95, 2012 Apr 23.
Artigo
Inglês
| MEDLINE | ID: mdl-22471323
11.
Molecular mechanisms underlying the effects of the small molecule AMC-04 on apoptosis: Roles of the activating transcription factor 4-C/EBP homologous protein-death receptor 5 pathway.
Chem Biol Interact
; 332: 109277, 2020 Dec 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33007289
12.
Hot spot profiles of SARS-CoV-2 and human ACE2 receptor protein protein interaction obtained by density functional tight binding fragment molecular orbital method.
Sci Rep
; 10(1): 16862, 2020 10 08.
Artigo
Inglês
| MEDLINE | ID: mdl-33033344
13.
PMFF: Development of a Physics-Based Molecular Force Field for Protein Simulation and Ligand Docking.
J Phys Chem B
; 124(6): 974-989, 2020 02 13.
Artigo
Inglês
| MEDLINE | ID: mdl-31939671
14.
Investigation of Hot Spot Region in XIAP Inhibitor Binding Site by Fragment Molecular Orbital Method.
Comput Struct Biotechnol J
; 17: 1217-1225, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-31673305
15.
Chromen-based TNF-alpha converting enzyme (TACE) inhibitors: design, synthesis, and biological evaluation.
Bioorg Med Chem
; 16(1): 530-5, 2008 Jan 01.
Artigo
Inglês
| MEDLINE | ID: mdl-17936631
16.
Synthesis of amide and urea derivatives of benzothiazole as Raf-1 inhibitor.
Eur J Med Chem
; 43(7): 1519-24, 2008 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-18023932
17.
Structure-activity relationship studies of a series of novel delta-lactam-based histone deacetylase inhibitors.
J Med Chem
; 50(11): 2737-41, 2007 May 31.
Artigo
Inglês
| MEDLINE | ID: mdl-17477518
18.
Novel focal adhesion kinase 1 inhibitor sensitizes lung cancer cells to radiation in a p53-independent manner.
Int J Oncol
; 51(5): 1583-1589, 2017 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-29048635
19.
The small molecule '1-(4-biphenylylcarbonyl)-4-(5-bromo-2-methoxybenzyl) piperazine oxalate' and its derivatives regulate global protein synthesis by inactivating eukaryotic translation initiation factor 2-alpha.
Cell Stress Chaperones
; 21(3): 485-97, 2016 May.
Artigo
Inglês
| MEDLINE | ID: mdl-26873011
20.
The HSP90 inhibitor, NVP-AUY922, sensitizes KRAS-mutant non-small cell lung cancer with intrinsic resistance to MEK inhibitor, trametinib.
Cancer Lett
; 372(1): 75-81, 2016 Mar 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26723875