Detalhe da pesquisa
1.
Phase 1 study of GSK3368715, a type I PRMT inhibitor, in patients with advanced solid tumors.
Br J Cancer
; 129(2): 309-317, 2023 08.
Artigo
Inglês
| MEDLINE | ID: mdl-37237172
2.
Activating PAX gene family paralogs to complement PAX5 leukemia driver mutations.
PLoS Genet
; 14(9): e1007642, 2018 09.
Artigo
Inglês
| MEDLINE | ID: mdl-30216339
3.
Recent progress toward epigenetic therapies: the example of mixed lineage leukemia.
Blood
; 121(24): 4847-53, 2013 Jun 13.
Artigo
Inglês
| MEDLINE | ID: mdl-23649466
4.
Targeted disruption of the EZH2-EED complex inhibits EZH2-dependent cancer.
Nat Chem Biol
; 9(10): 643-50, 2013 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-23974116
5.
Polycomb repressive complex 2 is required for MLL-AF9 leukemia.
Proc Natl Acad Sci U S A
; 109(13): 5028-33, 2012 Mar 27.
Artigo
Inglês
| MEDLINE | ID: mdl-22396593
6.
An unusual case of congenital primitive neuroectodermal tumor with ocular metastasis.
J Pediatr Hematol Oncol
; 34(2): e69-71, 2012 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-22052164
7.
Long-term polyclonal and multilineage engraftment of methylguanine methyltransferase P140K gene-modified dog hematopoietic cells in primary and secondary recipients.
Blood
; 113(21): 5094-103, 2009 May 21.
Artigo
Inglês
| MEDLINE | ID: mdl-19336761
8.
Evaluation of Cardiac Repolarization in the Randomized Phase 2 Study of Intermediate- or High-Risk Smoldering Multiple Myeloma Patients Treated with Daratumumab Monotherapy.
Adv Ther
; 38(2): 1328-1341, 2021 02.
Artigo
Inglês
| MEDLINE | ID: mdl-33474705
9.
Epigenetic regulation of protein translation in KMT2A-rearranged AML.
Exp Hematol
; 85: 57-69, 2020 05.
Artigo
Inglês
| MEDLINE | ID: mdl-32437908
10.
Daratumumab monotherapy for patients with intermediate-risk or high-risk smoldering multiple myeloma: a randomized, open-label, multicenter, phase 2 study (CENTAURUS).
Leukemia
; 34(7): 1840-1852, 2020 07.
Artigo
Inglês
| MEDLINE | ID: mdl-32024950
11.
Hematopoietic stem cell engraftment: a direct comparison between intramarrow and intravenous injection in nonhuman primates.
Exp Hematol
; 35(7): 1132-9, 2007 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-17588482
12.
The role of polycomb repressive complex 2 in early T-cell precursor acute lymphoblastic leukemia.
Mol Cell Oncol
; 5(5): e1166309, 2018.
Artigo
Inglês
| MEDLINE | ID: mdl-30263933
13.
AMPK/FIS1-Mediated Mitophagy Is Required for Self-Renewal of Human AML Stem Cells.
Cell Stem Cell
; 23(1): 86-100.e6, 2018 Jul 05.
Artigo
Inglês
| MEDLINE | ID: mdl-29910151
14.
In vivo selection and chemoprotection after drug resistance gene therapy in a nonmyeloablative allogeneic transplantation setting in dogs.
Hum Gene Ther
; 18(5): 451-6, 2007 May.
Artigo
Inglês
| MEDLINE | ID: mdl-17536975
15.
Methylguanine methyltransferase-mediated in vivo selection and chemoprotection of allogeneic stem cells in a large-animal model.
J Clin Invest
; 112(10): 1581-8, 2003 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-14617759
16.
MLL2, Not MLL1, Plays a Major Role in Sustaining MLL-Rearranged Acute Myeloid Leukemia.
Cancer Cell
; 31(6): 755-770.e6, 2017 06 12.
Artigo
Inglês
| MEDLINE | ID: mdl-28609655
17.
The Functional Role of PRC2 in Early T-cell Precursor Acute Lymphoblastic Leukemia (ETP-ALL) - Mechanisms and Opportunities.
Front Pediatr
; 4: 49, 2016.
Artigo
Inglês
| MEDLINE | ID: mdl-27242978
18.
Ezh2 Controls an Early Hematopoietic Program and Growth and Survival Signaling in Early T Cell Precursor Acute Lymphoblastic Leukemia.
Cell Rep
; 14(8): 1953-65, 2016 Mar 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26904942
19.
MLL1 and DOT1L cooperate with meningioma-1 to induce acute myeloid leukemia.
J Clin Invest
; 126(4): 1438-50, 2016 Apr 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26927674
20.
Histone profiles in cancer.
Pharmacol Ther
; 154: 87-109, 2015 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-26210403