Detalhe da pesquisa
1.
Phase 1 Trial of Antibody NI006 for Depletion of Cardiac Transthyretin Amyloid.
N Engl J Med
; 389(3): 239-250, 2023 Jul 20.
Artigo
Inglês
| MEDLINE | ID: mdl-37212440
2.
Comprehensive evaluation of human-derived anti-poly-GA antibodies in cellular and animal models of C9orf72 disease.
Proc Natl Acad Sci U S A
; 119(49): e2123487119, 2022 12 06.
Artigo
Inglês
| MEDLINE | ID: mdl-36454749
3.
Results from the long-term extension of PRIME: A randomized Phase 1b trial of aducanumab.
Alzheimers Dement
; 20(5): 3406-3415, 2024 May.
Artigo
Inglês
| MEDLINE | ID: mdl-38567735
4.
Lifestyle Affects Amyloid Burden and Cognition Differently in Men and Women.
Ann Neurol
; 92(3): 451-463, 2022 09.
Artigo
Inglês
| MEDLINE | ID: mdl-35598071
5.
Coregistered transcranial optoacoustic and magnetic resonance angiography of the human brain.
Opt Lett
; 48(3): 648-651, 2023 Feb 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36723554
6.
Addendum: The antibody aducanumab reduces Aß plaques in Alzheimer's disease.
Nature
; 546(7659): 564, 2017 06 21.
Artigo
Inglês
| MEDLINE | ID: mdl-28640269
7.
Early ß-amyloid accumulation in the brain is associated with peripheral T cell alterations.
Alzheimers Dement
; 19(12): 5642-5662, 2023 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-37314431
8.
Fe65 is the sole member of its family that mediates transcription regulated by the amyloid precursor protein.
J Cell Sci
; 133(17)2020 09 08.
Artigo
Inglês
| MEDLINE | ID: mdl-32843577
9.
Xeno-free induced pluripotent stem cell-derived neural progenitor cells for in vivo applications.
J Transl Med
; 20(1): 421, 2022 09 16.
Artigo
Inglês
| MEDLINE | ID: mdl-36114512
10.
Non-invasive imaging of tau-targeted probe uptake by whole brain multi-spectral optoacoustic tomography.
Eur J Nucl Med Mol Imaging
; 49(7): 2137-2152, 2022 06.
Artigo
Inglês
| MEDLINE | ID: mdl-35128565
11.
The antibody aducanumab reduces Aß plaques in Alzheimer's disease.
Nature
; 537(7618): 50-6, 2016 09 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27582220
12.
Lysine acetyltransferase Tip60 acetylates the APP adaptor Fe65 to increase its transcriptional activity.
Biol Chem
; 402(4): 481-499, 2021 03 26.
Artigo
Inglês
| MEDLINE | ID: mdl-33938178
13.
SWI and phase imaging reveal intracranial calcifications in the P301L mouse model of human tauopathy.
MAGMA
; 33(6): 769-781, 2020 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-32468149
14.
Diffusion Tensor Imaging Reveals Whole-Brain Microstructural Changes in the P301L Mouse Model of Tauopathy.
Neurodegener Dis
; 20(5-6): 173-184, 2020.
Artigo
Inglês
| MEDLINE | ID: mdl-33975312
15.
Development of an aggregate-selective, human-derived α-synuclein antibody BIIB054 that ameliorates disease phenotypes in Parkinson's disease models.
Neurobiol Dis
; 124: 276-288, 2019 04.
Artigo
Inglês
| MEDLINE | ID: mdl-30381260
16.
A fluorescent protein-readout for transcriptional activity reveals regulation of APP nuclear signaling by phosphorylation sites.
Biol Chem
; 400(9): 1191-1203, 2019 08 27.
Artigo
Inglês
| MEDLINE | ID: mdl-31120852
17.
Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in Vitro.
Am J Pathol
; 187(6): 1399-1412, 2017 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-28408124
18.
Extravascular CD3+ T Cells in Brains of Alzheimer Disease Patients Correlate with Tau but Not with Amyloid Pathology: An Immunohistochemical Study.
Neurodegener Dis
; 18(1): 49-56, 2018.
Artigo
Inglês
| MEDLINE | ID: mdl-29402847
19.
Hippocampal shape alterations are associated with regional Aß load in cognitively normal elderly individuals.
Eur J Neurosci
; 45(10): 1241-1251, 2017 05.
Artigo
Inglês
| MEDLINE | ID: mdl-27646656
20.
Reduced nitric oxide bioavailability mediates cerebroarterial dysfunction independent of cerebral amyloid angiopathy in a mouse model of Alzheimer's disease.
Am J Physiol Heart Circ Physiol
; 312(2): H232-H238, 2017 Feb 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27836896