Parameters of oxidative stress variation depending on the concentration of inorganic zinc compounds.

Zinc deficiency is a problem faced by a large number of people, a U.S. study showing that only 46% of the population aged over 71 years has the best amount of zinc in the body. Due to the very complex role of zinc deficiency in this trace, it can occur through a variety of symptoms affecting multiple body functions. Zinc was demonstrated to have the ability to neutralize free radicals protecting the body from the harmful effects of these effects, ultimately leading to atherosclerosis and cardiovascular disease derived from premature aging, the immune and immune disorders and increased risk of cancer. The purpose of the paper is to identify the role of antioxidant systems, with Zn2+ ions in the center of defense and decrease oxidative stress in dynamic interaction with malignant transformed cells.

The evaluation of non-enzymatic antioxidants effects in limiting tumor- associated oxidative stress, in a tumor rat model.

Active oxygen species are produced as a consequence of normal aerobic metabolism. Of these, free radicals are usually metabolized or inactivated in vivo by a team of antioxidants. Individual members are a trained team fighting antioxidants to prevent the generation of ROS, destroy or oxidizing potential of capture. In terms of physiological oxidative stress, induced tissue attack is minimal. A relative or absolute deficiency in the antioxidant defense may lead to increased oxidative stress and this event is associated with both the causes and consequences of diseases and cancer, included here. The aim of the study is to identify the role of antioxidant defense systems and the reduction of oxidative stress in dynamic growth and development of malignant tumors. Our in vivo study was developed and referred to carcinosarcoma carriers Wistar rats treated with non-enzymatic antioxidants: vitamin C, vitamin A, zinc salt (II), and arginine in various combinations. Treatment was initiated three weeks before tumor induction.

[Myotomia laminae globalis--a surgical method in correcting strabismus]. / "Myotomia laminae globalis"--metoda chirurgicala în corectarea strabismului.

The authors describe the surgical technique "myotomia laminae globalis", applied during 1990 and May 1994 in the Ophthalmological Clinic of Târgu-Mures, on 39 patients. The method was applied as singular intervention in 4 cases for completing the intervention through muscle resection. The proposed method proved to be simple, without danger and leading to good results.

[The visual prognosis in congenital cataract]. / Prognosticul vizual în cataracta congenitala.

The authors focus on the evolution of visual function postoperatorial, based on 349 patients which where diagnosed and operated by congenital cataract, during 1973-1992, in Tg. Mures Ophthalmological Clinic. All the interventions were done by discising the anterior capsula and washing the lens masses. After studying these cases, the authors conclude that visual prognosis of the operated eye depends on the presence of other congenital abnormalities, on the age of the patient and on the intervention type. In spite of all surgical progresses, congenital cataract still stands as an affection with reserved functional consequences.

[The Paltrinieri operation in treatment of pseudarthroses of the leg]. / Operatia Paltrinieri în tratamentul pseudartrozelor de gamba.

The authors present 8 cases of pseudarthroses of the tibia secondary to surgical and orthopaedic treatments of fractures of the leg, in whom para-focal osteotomia was performed. The Paltrinieri method is a simple and efficient intervention based on the biochemical principle of re-establishing a normal tibial axis, and on exclusion of the pseudarthrosis focus from under the influence of negative mechanical factors, an intervention which leads to a revival of the capacities of consolidation of the pseudarthrosis. The very good results obtained justify the recommendation ofthis therapeutical method in the treatment of pseudarthroses, especially of the suppurated pseudarthroses of the leg.