Detalhe da pesquisa
1.
Kynurenine 3-monooxygenase inhibition in blood ameliorates neurodegeneration.
Cell
; 145(6): 863-74, 2011 Jun 10.
Artigo
Inglês
| MEDLINE | ID: mdl-21640374
2.
The Probiotic Lactobacillus reuteri Preferentially Synthesizes Kynurenic Acid from Kynurenine.
Int J Mol Sci
; 25(7)2024 Mar 26.
Artigo
Inglês
| MEDLINE | ID: mdl-38612489
3.
A single prenatal lipopolysaccharide injection has acute, but not long-lasting, effects on cerebral kynurenine pathway metabolism in mice.
Eur J Neurosci
; 54(6): 5968-5981, 2021 09.
Artigo
Inglês
| MEDLINE | ID: mdl-34363411
4.
Assessment of Prenatal Kynurenine Metabolism Using Tissue Slices: Focus on the Neosynthesis of Kynurenic Acid in Mice.
Dev Neurosci
; 41(1-2): 102-111, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-31117076
5.
Tryptophan-2,3-dioxygenase (TDO) inhibition ameliorates neurodegeneration by modulation of kynurenine pathway metabolites.
Proc Natl Acad Sci U S A
; 113(19): 5435-40, 2016 May 10.
Artigo
Inglês
| MEDLINE | ID: mdl-27114543
6.
Key Enabling Technologies for Point-of-Care Diagnostics.
Sensors (Basel)
; 18(11)2018 Oct 24.
Artigo
Inglês
| MEDLINE | ID: mdl-30355989
7.
Tryptophan 2,3-dioxygenase and indoleamine 2,3-dioxygenase 1 make separate, tissue-specific contributions to basal and inflammation-induced kynurenine pathway metabolism in mice.
Biochim Biophys Acta
; 1860(11 Pt A): 2345-2354, 2016 11.
Artigo
Inglês
| MEDLINE | ID: mdl-27392942
8.
Prenatal Dynamics of Kynurenine Pathway Metabolism in Mice: Focus on Kynurenic Acid.
Dev Neurosci
; 39(6): 519-528, 2017.
Artigo
Inglês
| MEDLINE | ID: mdl-29080891
9.
Role of d-amino acid oxidase in the production of kynurenine pathway metabolites from d-tryptophan in mice.
J Neurochem
; 136(4): 804-814, 2016 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-26661897
10.
Restraint Stress during Pregnancy Rapidly Raises Kynurenic Acid Levels in Mouse Placenta and Fetal Brain.
Dev Neurosci
; 38(6): 458-468, 2016.
Artigo
Inglês
| MEDLINE | ID: mdl-28214871
11.
Prebiotic Treatment Increases Serum Butyrate in People With Schizophrenia: Results of an Open-Label Inpatient Pilot Clinical Trial.
J Clin Psychopharmacol
; 41(2): 200-202, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-33587401
12.
Reduced kynurenine pathway metabolism and cytokine expression in the prefrontal cortex of depressed individuals.
J Psychiatry Neurosci
; 41(6): 386-394, 2016 10.
Artigo
Inglês
| MEDLINE | ID: mdl-27070351
13.
Quinolinic acid/tryptophan ratios predict neurological disease in SIV-infected macaques and remain elevated in the brain under cART.
J Neurovirol
; 21(4): 449-63, 2015 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-25776527
14.
Targeted deletion of kynurenine 3-monooxygenase in mice: a new tool for studying kynurenine pathway metabolism in periphery and brain.
J Biol Chem
; 288(51): 36554-66, 2013 Dec 20.
Artigo
Inglês
| MEDLINE | ID: mdl-24189070
15.
A method for the determination of D-kynurenine in biological tissues.
Anal Bioanal Chem
; 405(30): 9747-54, 2013 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-24158577
16.
Deletion of quinolinate phosphoribosyltransferase gene accelerates frailty phenotypes and neuromuscular decline with aging in a sex-specific pattern.
Aging Cell
; 22(7): e13849, 2023 07.
Artigo
Inglês
| MEDLINE | ID: mdl-37078472
17.
Tryptophan challenge in individuals with schizophrenia and healthy controls: acute effects on circulating kynurenine and kynurenic acid, cognition and cerebral blood flow.
Neuropsychopharmacology
; 48(11): 1594-1601, 2023 10.
Artigo
Inglês
| MEDLINE | ID: mdl-37118058
18.
Enzymatic transamination of D-kynurenine generates kynurenic acid in rat and human brain.
J Neurochem
; 120(6): 1026-35, 2012 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-22224417
19.
Gas chromatography/tandem mass spectrometry detection of extracellular kynurenine and related metabolites in normal and lesioned rat brain.
Anal Biochem
; 421(2): 573-81, 2012 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-22239963
20.
Tryptophan Challenge in Healthy Controls and People with Schizophrenia: Acute Effects on Plasma Levels of Kynurenine, Kynurenic Acid and 5-Hydroxyindoleacetic Acid.
Pharmaceuticals (Basel)
; 15(8)2022 Aug 15.
Artigo
Inglês
| MEDLINE | ID: mdl-36015151