Detalhe da pesquisa
1.
Phase 1 study of GSK3368715, a type I PRMT inhibitor, in patients with advanced solid tumors.
Br J Cancer
; 129(2): 309-317, 2023 08.
Artigo
Inglês
| MEDLINE | ID: mdl-37237172
2.
Brain penetrant liver X receptor (LXR) modulators based on a 2,4,5,6-tetrahydropyrrolo[3,4-c]pyrazole core.
Bioorg Med Chem Lett
; 26(20): 5044-5050, 2016 10 15.
Artigo
Inglês
| MEDLINE | ID: mdl-27599745
3.
Identification of spirooxindole and dibenzoxazepine motifs as potent mineralocorticoid receptor antagonists.
Bioorg Med Chem
; 24(6): 1384-91, 2016 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26897089
4.
Regulation of sphingomyelin phosphodiesterase acid-like 3A gene (SMPDL3A) by liver X receptors.
Mol Pharmacol
; 82(4): 719-27, 2012 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-22810003
5.
Identification of hnRNP-A1 as a pharmacodynamic biomarker of type I PRMT inhibition in blood and tumor tissues.
Sci Rep
; 10(1): 22155, 2020 12 17.
Artigo
Inglês
| MEDLINE | ID: mdl-33335114
6.
Epigenetic modulation of estrogen receptor-alpha by pRb family proteins: a novel mechanism in breast cancer.
Cancer Res
; 67(16): 7731-7, 2007 Aug 15.
Artigo
Inglês
| MEDLINE | ID: mdl-17699777
7.
Discovery of a Novel, Orally Efficacious Liver X Receptor (LXR) ß Agonist.
J Med Chem
; 59(7): 3264-71, 2016 Apr 14.
Artigo
Inglês
| MEDLINE | ID: mdl-26990539
8.
Synergy between a lead proline-rich antibacterial peptide derivative and small molecule antibiotics.
Adv Exp Med Biol
; 611: 375-8, 2009.
Artigo
Inglês
| MEDLINE | ID: mdl-19400232
9.
The medicinal chemistry of liver X receptor (LXR) modulators.
J Med Chem
; 57(17): 7182-205, 2014 Sep 11.
Artigo
Inglês
| MEDLINE | ID: mdl-24832115
10.
Alternative stabilities of a proline-rich antibacterial peptide in vitro and in vivo.
Protein Sci
; 17(7): 1249-55, 2008 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-18413862