Detalhe da pesquisa
1.
Transcriptional reprogramming restores UBE3A brain-wide and rescues behavioral phenotypes in an Angelman syndrome mouse model.
Mol Ther
; 31(4): 1088-1105, 2023 04 05.
Artigo
Inglês
| MEDLINE | ID: mdl-36641623
2.
Determinants of heritable gene silencing for KRAB-dCas9 + DNMT3 and Ezh2-dCas9 + DNMT3 hit-and-run epigenome editing.
Nucleic Acids Res
; 50(6): 3239-3253, 2022 04 08.
Artigo
Inglês
| MEDLINE | ID: mdl-35234927
3.
Functional rescue in an Angelman syndrome model following treatment with lentivector transduced hematopoietic stem cells.
Hum Mol Genet
; 30(12): 1067-1083, 2021 06 09.
Artigo
Inglês
| MEDLINE | ID: mdl-33856035
4.
Diverse Molecular Mechanisms Contribute to Differential Expression of Human Duplicated Genes.
Mol Biol Evol
; 38(8): 3060-3077, 2021 07 29.
Artigo
Inglês
| MEDLINE | ID: mdl-34009325
5.
Aberrant promoter methylation contributes to LRIG1 silencing in basal/triple-negative breast cancer.
Br J Cancer
; 127(3): 436-448, 2022 08.
Artigo
Inglês
| MEDLINE | ID: mdl-35440669
6.
Artificial escape from XCI by DNA methylation editing of the CDKL5 gene.
Nucleic Acids Res
; 48(5): 2372-2387, 2020 03 18.
Artigo
Inglês
| MEDLINE | ID: mdl-31925439
7.
Imprinting effects of UBE3A loss on synaptic gene networks and Wnt signaling pathways.
Hum Mol Genet
; 28(22): 3842-3852, 2019 11 15.
Artigo
Inglês
| MEDLINE | ID: mdl-31625566
8.
Versatile 3' Functionalization of CRISPR Single Guide RNA.
Chembiochem
; 21(11): 1633-1640, 2020 06 02.
Artigo
Inglês
| MEDLINE | ID: mdl-31943634
9.
dCas9-based epigenome editing suggests acquisition of histone methylation is not sufficient for target gene repression.
Nucleic Acids Res
; 45(17): 9901-9916, 2017 Sep 29.
Artigo
Inglês
| MEDLINE | ID: mdl-28973434
10.
Architecture of the human regulatory network derived from ENCODE data.
Nature
; 489(7414): 91-100, 2012 Sep 06.
Artigo
Inglês
| MEDLINE | ID: mdl-22955619
11.
Effects on the transcriptome upon deletion of a distal element cannot be predicted by the size of the H3K27Ac peak in human cells.
Nucleic Acids Res
; 44(9): 4123-33, 2016 05 19.
Artigo
Inglês
| MEDLINE | ID: mdl-26743005
12.
Protein Delivery of an Artificial Transcription Factor Restores Widespread Ube3a Expression in an Angelman Syndrome Mouse Brain.
Mol Ther
; 24(3): 548-55, 2016 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-26727042
13.
Discovering hematopoietic mechanisms through genome-wide analysis of GATA factor chromatin occupancy.
Mol Cell
; 36(4): 667-81, 2009 Nov 25.
Artigo
Inglês
| MEDLINE | ID: mdl-19941826
14.
A genome-wide analysis of Cas9 binding specificity using ChIP-seq and targeted sequence capture.
Nucleic Acids Res
; 43(6): 3389-404, 2015 Mar 31.
Artigo
Inglês
| MEDLINE | ID: mdl-25712100
15.
Functional DNA methylation differences between tissues, cell types, and across individuals discovered using the M&M algorithm.
Genome Res
; 23(9): 1522-40, 2013 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-23804400
16.
Spark: a navigational paradigm for genomic data exploration.
Genome Res
; 22(11): 2262-9, 2012 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-22960372
17.
De novo genome assembly of the economically important weed horseweed using integrated data from multiple sequencing platforms.
Plant Physiol
; 166(3): 1241-54, 2014 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-25209985
18.
Global analysis of ZNF217 chromatin occupancy in the breast cancer cell genome reveals an association with ERalpha.
BMC Genomics
; 15: 520, 2014 Jun 24.
Artigo
Inglês
| MEDLINE | ID: mdl-24962896
19.
Genetic framework for GATA factor function in vascular biology.
Proc Natl Acad Sci U S A
; 108(33): 13641-6, 2011 Aug 16.
Artigo
Inglês
| MEDLINE | ID: mdl-21808000
20.
Integration of CTCF Loops, Methylome, and Transcriptome in Differentiating LUHMES as a Model for Imprinting Dynamics of the 15q11-q13 Locus in Human Neurons.
bioRxiv
; 2024 Mar 29.
Artigo
Inglês
| MEDLINE | ID: mdl-38586056