Detalhe da pesquisa
1.
Discovery of Small-Molecule Selective mTORC1 Inhibitors via Direct Inhibition of Glucose Transporters.
Cell Chem Biol
; 26(9): 1203-1213.e13, 2019 09 19.
Artigo
Inglês
| MEDLINE | ID: mdl-31231029
2.
Synthesis and discovery of macrocyclic polyoxygenated bis-7-azaindolylmaleimides as a novel series of potent and highly selective glycogen synthase kinase-3beta inhibitors.
J Med Chem
; 46(19): 4021-31, 2003 Sep 11.
Artigo
Inglês
| MEDLINE | ID: mdl-12954055
3.
Discovery of novel selective norepinephrine inhibitors: 1-(2-morpholin-2-ylethyl)-3-aryl-1,3-dihydro-2,1,3-benzothiadiazole 2,2-dioxides (WYE-114152).
J Med Chem
; 54(19): 6824-31, 2011 Oct 13.
Artigo
Inglês
| MEDLINE | ID: mdl-21916421
4.
Discovery of novel selective norepinephrine reuptake inhibitors: 4-[3-aryl-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-1-(methylamino)butan-2-ols (WYE-103231).
J Med Chem
; 53(11): 4511-21, 2010 Jun 10.
Artigo
Inglês
| MEDLINE | ID: mdl-20462211
5.
Samarium-promoted coupling of 1,10-phenanthroline with carbonyl compounds for synthesis of new ligands.
J Org Chem
; 69(8): 2809-15, 2004 Apr 16.
Artigo
Inglês
| MEDLINE | ID: mdl-15074932
6.
Design, synthesis, and biological evaluation of novel 7-azaindolyl-heteroaryl-maleimides as potent and selective glycogen synthase kinase-3beta (GSK-3beta) inhibitors.
Bioorg Med Chem
; 12(12): 3167-85, 2004 Jun 15.
Artigo
Inglês
| MEDLINE | ID: mdl-15158785