RESUMO
INTRODUCTION: Angiomyxolipoma (AML) is a rare variant of benign lipoma with characteristic histopathological and immuno-histochemical features. It consists of fatty tissue admixed with myxoid stroma and blood vessels. It was first described by Mai et al. in 1996 [1], with a total number of 19 cases reported since. PRESENTATION: This is the first report of an AML in subcutaneous tissue of the face, presenting as a 4-month old cystic lesion in a 78-year old lady. Diagnosis was based on radiological and histopathological with cytochemical findings. DISCUSSION: It is important to distinguish this lesion as distinct from malignant subcutaneous lesions of fatty tissue, especially with short history as seen in our case. CONCLUSION: Precise diagnosis of angiomyxolipoma is important to avoid unnecessary investigations, stress and misdiagnosis of myxoid liposarcoma.