Detalhe da pesquisa
1.
Prediction of inotropic effect based on calcium transients in human iPSC-derived cardiomyocytes and machine learning.
Toxicol Appl Pharmacol
; 459: 116342, 2023 01 15.
Artigo
Inglês
| MEDLINE | ID: mdl-36502871
2.
Prediction of In Vivo Pharmacokinetic Parameters and Time-Exposure Curves in Rats Using Machine Learning from the Chemical Structure.
Mol Pharm
; 19(5): 1488-1504, 2022 05 02.
Artigo
Inglês
| MEDLINE | ID: mdl-35412314
3.
Machine Learning Models for Human In Vivo Pharmacokinetic Parameters with In-House Validation.
Mol Pharm
; 18(12): 4520-4530, 2021 12 06.
Artigo
Inglês
| MEDLINE | ID: mdl-34758626
4.
Biological insights into the expression of translation initiation factors from recombinant CHOK1SV cell lines and their relationship to enhanced productivity.
Biochem J
; 472(3): 261-73, 2015 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-26420881
5.
Artificial intelligence for compound pharmacokinetics prediction.
Curr Opin Struct Biol
; 79: 102546, 2023 04.
Artigo
Inglês
| MEDLINE | ID: mdl-36804676
6.
Deriving waveform parameters from calcium transients in human iPSC-derived cardiomyocytes to predict cardiac activity with machine learning.
Stem Cell Reports
; 17(3): 556-568, 2022 03 08.
Artigo
Inglês
| MEDLINE | ID: mdl-35148844
7.
Gaussian processes for classification: QSAR modeling of ADMET and target activity.
J Chem Inf Model
; 50(6): 1053-61, 2010 Jun 28.
Artigo
Inglês
| MEDLINE | ID: mdl-20433177
8.
Beyond profiling: using ADMET models to guide decisions.
Chem Biodivers
; 6(11): 2144-51, 2009 Nov.
Artigo
Inglês
| MEDLINE | ID: mdl-19937845
9.
Aggregation risk prediction for antibodies and its application to biotherapeutic development.
MAbs
; 7(2): 352-63, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-25760769
10.
Early implementation of QbD in biopharmaceutical development: a practical example.
Biomed Res Int
; 2015: 605427, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-26075248
11.
Automatic QSAR modeling of ADME properties: blood-brain barrier penetration and aqueous solubility.
J Comput Aided Mol Des
; 22(6-7): 431-40, 2008.
Artigo
Inglês
| MEDLINE | ID: mdl-18273554
12.
Gaussian processes: a method for automatic QSAR modeling of ADME properties.
J Chem Inf Model
; 47(5): 1847-57, 2007.
Artigo
Inglês
| MEDLINE | ID: mdl-17602549