Detalhe da pesquisa
1.
Investigation into the Use of Encorafenib to Develop Potential PROTACs Directed against BRAFV600E Protein.
Molecules
; 27(23)2022 Dec 03.
Artigo
Inglês
| MEDLINE | ID: mdl-36500607
2.
Discovery of methylated circulating DNA biomarkers for comprehensive non-invasive monitoring of treatment response in metastatic colorectal cancer.
Gut
; 67(11): 1995-2005, 2018 11.
Artigo
Inglês
| MEDLINE | ID: mdl-28982739
3.
Emergence of MET hyper-amplification at progression to MET and BRAF inhibition in colorectal cancer.
Br J Cancer
; 117(3): 347-352, 2017 Jul 25.
Artigo
Inglês
| MEDLINE | ID: mdl-28654634
4.
Preclinical efficacy of carfilzomib in BRAF-mutant colorectal cancer models.
Mol Oncol
; 18(6): 1552-1570, 2024 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-38348572
5.
Exploring circular MET RNA as a potential biomarker in tumors exhibiting high MET activity.
J Exp Clin Cancer Res
; 42(1): 120, 2023 May 12.
Artigo
Inglês
| MEDLINE | ID: mdl-37170152
6.
Werner Helicase Is a Synthetic-Lethal Vulnerability in Mismatch Repair-Deficient Colorectal Cancer Refractory to Targeted Therapies, Chemotherapy, and Immunotherapy.
Cancer Discov
; 11(8): 1923-1937, 2021 08.
Artigo
Inglês
| MEDLINE | ID: mdl-33837064
7.
Reliance upon ancestral mutations is maintained in colorectal cancers that heterogeneously evolve during targeted therapies.
Nat Commun
; 9(1): 2287, 2018 06 12.
Artigo
Inglês
| MEDLINE | ID: mdl-29895949
8.
Bromodomain inhibition exerts its therapeutic potential in malignant pleural mesothelioma by promoting immunogenic cell death and changing the tumor immune-environment.
Oncoimmunology
; 7(3): e1398874, 2018.
Artigo
Inglês
| MEDLINE | ID: mdl-29399399
9.
BCAM and LAMA5 Mediate the Recognition between Tumor Cells and the Endothelium in the Metastatic Spreading of KRAS-Mutant Colorectal Cancer.
Clin Cancer Res
; 22(19): 4923-4933, 2016 Oct 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27143691
10.
MET-Driven Resistance to Dual EGFR and BRAF Blockade May Be Overcome by Switching from EGFR to MET Inhibition in BRAF-Mutated Colorectal Cancer.
Cancer Discov
; 6(9): 963-71, 2016 09.
Artigo
Inglês
| MEDLINE | ID: mdl-27325282
11.
Molecular Landscape of Acquired Resistance to Targeted Therapy Combinations in BRAF-Mutant Colorectal Cancer.
Cancer Res
; 76(15): 4504-15, 2016 08 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27312529