Detalhe da pesquisa
1.
A randomized, controlled trial to evaluate the effect of an anti-interleukin-9 monoclonal antibody in adults with uncontrolled asthma.
Respir Res
; 14: 93, 2013 Sep 19.
Artigo
Inglês
| MEDLINE | ID: mdl-24050312
2.
Safety profile and clinical activity of multiple subcutaneous doses of MEDI-528, a humanized anti-interleukin-9 monoclonal antibody, in two randomized phase 2a studies in subjects with asthma.
BMC Pulm Med
; 11: 14, 2011 Feb 28.
Artigo
Inglês
| MEDLINE | ID: mdl-21356110
3.
An open-label, single-dose bioavailability study of the pharmacokinetics of CAT-354 after subcutaneous and intravenous administration in healthy males.
Br J Clin Pharmacol
; 69(6): 645-55, 2010 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-20565456
4.
Binding of upstream stimulatory factor 1 to the E-box regulates the 4G/5G polymorphism-dependent plasminogen activator inhibitor 1 expression in mast cells.
J Allergy Clin Immunol
; 121(4): 1006-1012.e2, 2008 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-18234320
5.
Injectable DaxibotulinumtoxinA in Cervical Dystonia: A Phase 2 Dose-Escalation Multicenter Study.
Mov Disord Clin Pract
; 5(3): 273-282, 2018.
Artigo
Inglês
| MEDLINE | ID: mdl-30009213
6.
Upstream stimulating factor-1 mediates the E-box-dependent transcriptional repression of the plasminogen activator inhibitor-1 gene in human mast cells.
FEBS Lett
; 581(23): 4485-90, 2007 Sep 18.
Artigo
Inglês
| MEDLINE | ID: mdl-17765897
7.
Phase 2, randomised placebo-controlled trial to evaluate the efficacy and safety of an anti-GM-CSF antibody (KB003) in patients with inadequately controlled asthma.
BMJ Open
; 6(1): e007709, 2016 Jan 06.
Artigo
Inglês
| MEDLINE | ID: mdl-26739717
8.
Mast cell mediators in airway remodeling.
Chem Immunol Allergy
; 87: 85-100, 2005.
Artigo
Inglês
| MEDLINE | ID: mdl-16107765
9.
Plasminogen activator inhibitor-1 in the pathogenesis of asthma.
Exp Biol Med (Maywood)
; 229(2): 138-46, 2004 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-14734792
10.
Smoking and idiopathic pulmonary fibrosis.
Pulm Med
; 2012: 808260, 2012.
Artigo
Inglês
| MEDLINE | ID: mdl-22448328
11.
Biology of the interleukin-9 pathway and its therapeutic potential for the treatment of asthma.
Inflamm Allergy Drug Targets
; 10(3): 180-6, 2011 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-21428906
12.
Importance of mast cells in the pathophysiology of asthma.
Clin Rev Allergy Immunol
; 22(2): 161-74, 2002 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-11975421
13.
Hypoxia-induced HIF-1 alpha accumulation is augmented in a co-culture of keloid fibroblasts and human mast cells: involvement of ERK1/2 and PI-3K/Akt.
Exp Cell Res
; 312(2): 145-55, 2006 Jan 15.
Artigo
Inglês
| MEDLINE | ID: mdl-16289155
14.
Amphiregulin expression in human mast cells and its effect on the primary human lung fibroblasts.
J Allergy Clin Immunol
; 115(2): 287-94, 2005 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-15696083
15.
Preformed enzymes in mast cell granules and their potential role in allergic rhinitis.
Curr Allergy Asthma Rep
; 3(3): 266-72, 2003 May.
Artigo
Inglês
| MEDLINE | ID: mdl-12662477
16.
PAI-1 promotes extracellular matrix deposition in the airways of a murine asthma model.
Biochem Biophys Res Commun
; 294(5): 1155-60, 2002 Jun 28.
Artigo
Inglês
| MEDLINE | ID: mdl-12074598
17.
(S,S)-formoterol increases the production of IL-4 in mast cells and the airways of a murine asthma model.
Int Arch Allergy Immunol
; 133(4): 380-8, 2004 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-15031612
18.
Regulation of activin A expression in mast cells and asthma: its effect on the proliferation of human airway smooth muscle cells.
J Immunol
; 170(8): 4045-52, 2003 Apr 15.
Artigo
Inglês
| MEDLINE | ID: mdl-12682233