Detalhe da pesquisa
1.
Molecular action of larvicidal flavonoids on ecdysteroidogenic glutathione S-transferase Noppera-bo in Aedes aegypti.
BMC Biol
; 20(1): 43, 2022 02 17.
Artigo
Inglês
| MEDLINE | ID: mdl-35172816
2.
Dephospho-Coenzyme A Kinase Is an Exploitable Drug Target against Plasmodium falciparum: Identification of Selective Inhibitors by High-Throughput Screening of a Large Chemical Compound Library.
Antimicrob Agents Chemother
; 66(11): e0042022, 2022 11 15.
Artigo
Inglês
| MEDLINE | ID: mdl-36314787
3.
Oxytocin/vasopressin-like peptide inotocin regulates cuticular hydrocarbon synthesis and water balancing in ants.
Proc Natl Acad Sci U S A
; 116(12): 5597-5606, 2019 03 19.
Artigo
Inglês
| MEDLINE | ID: mdl-30842287
4.
Application of Acoustic Ejection MS System to High-Throughput Screening for SARS-CoV-2 3CL Protease Inhibitors.
Chem Pharm Bull (Tokyo)
; 70(3): 199-201, 2022 Mar 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34937844
5.
An integrated approach to unravel a crucial structural property required for the function of the insect steroidogenic Halloween protein Noppera-bo.
J Biol Chem
; 295(20): 7154-7167, 2020 05 15.
Artigo
Inglês
| MEDLINE | ID: mdl-32241910
6.
Identification of novel compounds that inhibit SnRK2 kinase activity by high-throughput screening.
Biochem Biophys Res Commun
; 537: 57-63, 2021 01 22.
Artigo
Inglês
| MEDLINE | ID: mdl-33385806
7.
Metabolic-Pathway-Oriented Screening Targeting S-Adenosyl-l-methionine Reveals the Epigenetic Remodeling Activities of Naturally Occurring Catechols.
J Am Chem Soc
; 142(1): 21-26, 2020 01 08.
Artigo
Inglês
| MEDLINE | ID: mdl-31869215
8.
Effects of pharmacist participation in chronic kidney disease (CKD) network and CKD manual distribution on drug-related kidney injury.
Pharmacoepidemiol Drug Saf
; 28(6): 887-896, 2019 06.
Artigo
Inglês
| MEDLINE | ID: mdl-31038268
9.
Development of a Novel Intraocular-Pressure-Lowering Therapy Targeting ATX.
Biol Pharm Bull
; 42(11): 1926-1935, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-31685776
10.
Novel indole and benzothiophene ring derivatives showing differential modulatory activity against human epithelial sodium channel subunits, ENaC ß and γ.
Biosci Biotechnol Biochem
; 83(2): 243-250, 2019 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-30343635
11.
Structural development of 1,2,3,4-tetrahydroisoquinoline-type positive allosteric modulators of prostacyclin receptor (IPPAMs) to improve metabolic stability, and investigation of metabolic fate.
Bioorg Med Chem Lett
; 27(15): 3572-3575, 2017 08 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28587821
12.
Synthesis of both enantiomers of 1,2,3,4-tetrahydroisoquinoline derivative IPPAM-1 and enantio-dependency of its positive allosteric modulation of prostacyclin receptor.
Bioorg Med Chem Lett
; 27(11): 2567-2570, 2017 06 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28462839
13.
Discovery of benzo[g]indoles as a novel class of non-covalent Keap1-Nrf2 protein-protein interaction inhibitor.
Bioorg Med Chem Lett
; 27(22): 5006-5009, 2017 11 15.
Artigo
Inglês
| MEDLINE | ID: mdl-29037947
14.
Development of Chemical Tools to Monitor and Control Isoaspartyl Peptide Methyltransferase Activity.
Angew Chem Int Ed Engl
; 56(1): 153-157, 2017 01 02.
Artigo
Inglês
| MEDLINE | ID: mdl-27933714
15.
A novel diacylglycerol kinase α-selective inhibitor, CU-3, induces cancer cell apoptosis and enhances immune response.
J Lipid Res
; 57(3): 368-79, 2016 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-26768655
16.
Development of a potent and selective FLT3 kinase inhibitor by systematic expansion of a non-selective fragment-screening hit.
Bioorg Med Chem Lett
; 26(9): 2370-4, 2016 May 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26995531
17.
Synthesis of Keap1-phosphorylated p62 and Keap1-Nrf2 protein-protein interaction inhibitors and their inhibitory activity.
Bioorg Med Chem Lett
; 26(24): 5956-5959, 2016 12 15.
Artigo
Inglês
| MEDLINE | ID: mdl-27839920
18.
Identification of a Dual Inhibitor of SRPK1 and CK2 That Attenuates Pathological Angiogenesis of Macular Degeneration in Mice.
Mol Pharmacol
; 88(2): 316-25, 2015 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-25993998
19.
Sphingosine, a modulator of human translesion DNA polymerase activity.
J Biol Chem
; 289(31): 21663-72, 2014 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24928506
20.
Artificial Ligands of Streptavidin (ALiS): Discovery, Characterization, and Application for Reversible Control of Intracellular Protein Transport.
J Am Chem Soc
; 137(33): 10464-7, 2015 Aug 26.
Artigo
Inglês
| MEDLINE | ID: mdl-26261872