Detalhe da pesquisa
1.
Adrenals Contribute to Growth of Castration-Resistant VCaP Prostate Cancer Xenografts.
Am J Pathol
; 188(12): 2890-2901, 2018 12.
Artigo
Inglês
| MEDLINE | ID: mdl-30273606
2.
Antiandrogens Reduce Intratumoral Androgen Concentrations and Induce Androgen Receptor Expression in Castration-Resistant Prostate Cancer Xenografts.
Am J Pathol
; 188(1): 216-228, 2018 01.
Artigo
Inglês
| MEDLINE | ID: mdl-29126837
3.
Castration induces up-regulation of intratumoral androgen biosynthesis and androgen receptor expression in an orthotopic VCaP human prostate cancer xenograft model.
Am J Pathol
; 184(8): 2163-73, 2014 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-24949550
4.
First-in-Class Small Molecule to Inhibit CYP11A1 and Steroid Hormone Biosynthesis.
Mol Cancer Ther
; 21(12): 1765-1776, 2022 12 02.
Artigo
Inglês
| MEDLINE | ID: mdl-36129801
5.
High intratumoral dihydrotestosterone is associated with antiandrogen resistance in VCaP prostate cancer xenografts in castrated mice.
iScience
; 25(5): 104287, 2022 May 20.
Artigo
Inglês
| MEDLINE | ID: mdl-35573198
6.
Sexual incentive motivation in male rats requires both androgens and estrogens.
Horm Behav
; 58(2): 341-51, 2010 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-19769979
7.
ODM-204, a Novel Dual Inhibitor of CYP17A1 and Androgen Receptor: Early Results from Phase I Dose Escalation in Men with Castration-resistant Prostate Cancer.
Eur Urol Focus
; 6(1): 63-70, 2020 01 15.
Artigo
Inglês
| MEDLINE | ID: mdl-30194031
8.
Discovery and development of ODM-204: A Novel nonsteroidal compound for the treatment of castration-resistant prostate cancer by blocking the androgen receptor and inhibiting CYP17A1.
J Steroid Biochem Mol Biol
; 192: 105115, 2019 09.
Artigo
Inglês
| MEDLINE | ID: mdl-29438723
9.
ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor Immunity.
Mol Cancer Ther
; 18(1): 28-38, 2019 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30301864
10.
Optimized design and analysis of preclinical intervention studies in vivo.
Sci Rep
; 6: 30723, 2016 08 02.
Artigo
Inglês
| MEDLINE | ID: mdl-27480578
11.
Discovery of ODM-201, a new-generation androgen receptor inhibitor targeting resistance mechanisms to androgen signaling-directed prostate cancer therapies.
Sci Rep
; 5: 12007, 2015 Jul 03.
Artigo
Inglês
| MEDLINE | ID: mdl-26137992