Many-Body Radiative Decay in Strongly Interacting Rydberg Ensembles.

When atoms are excited to high-lying Rydberg states they interact strongly with dipolar forces. The resulting state-dependent level shifts allow us to study many-body systems displaying intriguing nonequilibrium phenomena, such as constrained spin systems, and are at the heart of numerous technological applications, e.g., in quantum simulation and computation platforms. Here, we show that these interactions also have a significant impact on dissipative effects caused by the inevitable coupling of Rydberg atoms to the surrounding electromagnetic field. We demonstrate that their presence modifies the frequency of the photons emitted from the Rydberg atoms, making it dependent on the local neighborhood of the emitting atom. Interactions among Rydberg atoms thus turn spontaneous emission into a many-body process which manifests, in a thermodynamically consistent Markovian setting, in the emergence of collective jump operators in the quantum master equation governing the dynamics. We discuss how this collective dissipation-stemming from a mechanism different from the much studied superradiance and subradiance-accelerates decoherence and affects dissipative phase transitions in Rydberg ensembles.

Dynamical Phases and Quantum Correlations in an Emitter-Waveguide System with Feedback.

We investigate the creation and control of emergent collective behavior and quantum correlations using feedback in an emitter-waveguide system using a minimal model. Employing homodyne detection of photons emitted from a laser-driven emitter ensemble into the modes of a waveguide allows for the generation of intricate dynamical phases. In particular, we show the emergence of a time-crystal phase, the transition to which is controlled by the feedback strength. Feedback enables furthermore the control of many-body quantum correlations, which become manifest in spin squeezing in the emitter ensemble. Developing a theory for the dynamics of fluctuation operators we discuss how the feedback strength controls the squeezing and investigate its temporal dynamics and dependence on system size. The largely analytical results allow to quantify spin squeezing and fluctuations in the limit of large number of emitters, revealing critical scaling of the squeezing close to the transition to the time crystal. Our study corroborates the potential of integrated emitter-waveguide systems-which feature highly controllable photon emission channels-for the exploration of collective quantum phenomena and the generation of resources, such as squeezed states, for quantum enhanced metrology.

Collectively Enhanced Chiral Photon Emission from an Atomic Array near a Nanofiber.

Emitter ensembles interact collectively with the radiation field. In the case of a one-dimensional array of atoms near a nanofiber, this collective light-matter interaction does not only lead to an increased photon coupling to the guided modes within the fiber, but also to a drastic enhancement of the chirality in the photon emission. We show that near-perfect chirality can be achieved already for moderately sized ensembles, containing 10 to 15 atoms, by phase matching a superradiant collective guided emission mode via an external laser field. This is of importance for developing an efficient interface between atoms and waveguide structures with unidirectional coupling, with applications in quantum computing and communication such as the development of nonreciprocal photon devices or quantum information transfer channels.

Substrate-induced shifts and screening in the fluorescence spectra of supramolecular adsorbed organic monolayers.

We have investigated the influence of the substrate on the fluorescence of adsorbed organic molecules. Monolayer films of perylene-3,4,9,10-tetracarboxylic-3,4,9,10-diimide (PTCDI), a supramolecular network formed from PTCDI and melamine, and perylene-3,4,9,10-tetracarboxylic-3,4,9,10-dianhydride have been deposited on hexagonal boron nitride (hBN). The principal peaks in the fluorescence spectra of these films were red-shifted by up to 0.37 eV relative to published measurements for molecules in helium droplets. Smaller shifts (∼0.03 eV) arising from interactions between neighbouring molecules are investigated by comparing the fluorescence of distinct arrangements of PTCDI, which are templated by supramolecular self-assembly and determined with molecular resolution using atomic force microscopy under ambient conditions. We compare our experimental results with red-shifts calculated using a combination of a perturbative model and density functional theory which account for, respectively, resonant and non-resonant effects of a dielectric hBN substrate. We show that the substrate gives rise to a red-shift in the fluorescence of an adsorbed molecule and also screens the interactions between neighbouring transition dipole moments; both these effects depend on the refractive index of the substrate.

Facilitated spin models of dissipative quantum glasses.

We introduce a class of dissipative quantum spin models with local interactions and without quenched disorder that show glassy behavior. These models are the quantum analogs of the classical facilitated spin models. Just like their classical counterparts, quantum facilitated models display complex glassy dynamics despite the fact that their stationary state is essentially trivial. In these systems, dynamical arrest is a consequence of kinetic constraints and not of static ordering. These models display a quantum version of dynamic heterogeneity: the dynamics toward relaxation is spatially correlated despite the absence of static correlations. Associated dynamical fluctuation phenomena such as decoupling of time scales is also observed. Moreover, we find that close to the classical limit, quantum fluctuations can enhance glassiness, as recently reported for quantum liquids.

Rydberg rings.

Atoms in highly excited Rydberg states exhibit remarkable properties such as large polarizability and strong interactions. This makes them interesting for a manifold of applications ranging from electric field sensors to carriers and mediators of quantum information and renders them into a powerful tool for studying quantum phenomena in strongly interacting many-particle systems. In this article we illuminate perspectives for the study of the relaxation and thermalization dynamics of closed many-body quantum systems using alkali atoms that are held in a ring lattice and excited to Rydberg states. Moreover, we show that Rydberg atoms confined to lattices offer exciting possibilities for the creation of entangled many-body quantum states which can serve as a resource for the generation of non-classical light.

Thermalization in a coherently driven ensemble of two-level systems.

We investigate the coherent quantum time evolution of a driven mesoscopic chain of two-level systems that interact via the van der Waals interaction in their excited state. The Hamiltonian is the sum of a classical lattice gas Hamiltonian and an off-diagonal driving term without classical counterpart. Starting from a product state we observe-beyond a certain interaction strength-thermalization of the system with respect to observables of the classical lattice gas. This transition can be studied experimentally with Rydberg atoms, ions, or polar molecules. We suggest how to experimentally determine the temperature of the thermal state which should allow for thermometry of the internal degrees of freedom of cold Rydberg gases whose external dynamics is frozen.

Discovery of Imidazo[1,2-a]pyrazines and Pyrazolo[1,5-c]pyrimidines as TARP γ-8 Selective AMPAR Negative Modulators.

This report discloses the discovery and characterization of imidazo[1,2-a]pyrazines and pyrazolo[1,5-c]pyrimidines as selective negative modulators of α-amino-3-hydroxy-5-methylisoxazole-4-propionate receptors (AMPARs) associated with transmembrane AMPAR regulatory protein γ-8. Imidazopyrazine 5 was initially identified as a promising γ-8 selective high-throughput screening hit, and subsequent structure-activity relationship optimization yielded subnanomolar, brain penetrant leads. Replacement of the imidazopyrazine core with an isosteric pyrazolopyrimidine scaffold improved microsomal stability and efflux liabilities to provide 26, JNJ-61432059. Following oral administration, 26 exhibited time- and dose-dependent AMPAR/γ-8 receptor occupancy in mouse hippocampus, which resulted in robust seizure protection in corneal kindling and pentylenetetrazole (PTZ) anticonvulsant models.

Out-of-equilibrium evolution of kinetically constrained many-body quantum systems under purely dissipative dynamics.

We explore the relaxation dynamics of quantum many-body systems that undergo purely dissipative dynamics through non-classical jump operators that can establish quantum coherence. Our goal is to shed light on the differences in the relaxation dynamics that arise in comparison to systems evolving via classical rate equations. In particular, we focus on a scenario where both quantum and classical dissipative evolution lead to a stationary state with the same values of diagonal or "classical" observables. As a basis for illustrating our ideas we use spin systems whose dynamics becomes correlated and complex due to dynamical constraints, inspired by kinetically constrained models (KCMs) of classical glasses. We show that in the quantum case the relaxation can be orders of magnitude slower than the classical one due to the presence of quantum coherences. Aspects of these idealized quantum KCMs become manifest in a strongly interacting Rydberg gas under electromagnetically induced transparency (EIT) conditions in an appropriate limit. Beyond revealing a link between this Rydberg gas and the rather abstract dissipative KCMs of quantum glassy systems, our study sheds light on the limitations of the use of classical rate equations for capturing the non-equilibrium behavior of this many-body system.