Detalhe da pesquisa
1.
Stapled α-helical peptide drug development: a potent dual inhibitor of MDM2 and MDMX for p53-dependent cancer therapy.
Proc Natl Acad Sci U S A
; 110(36): E3445-54, 2013 Sep 03.
Artigo
Inglês
| MEDLINE | ID: mdl-23946421
2.
Aptamer ARC19499 mediates a procoagulant hemostatic effect by inhibiting tissue factor pathway inhibitor.
Blood
; 117(20): 5514-22, 2011 May 19.
Artigo
Inglês
| MEDLINE | ID: mdl-21389323
3.
Discovery of Sulanemadlin (ALRN-6924), the First Cell-Permeating, Stabilized α-Helical Peptide in Clinical Development.
J Med Chem
; 66(14): 9401-9417, 2023 07 27.
Artigo
Inglês
| MEDLINE | ID: mdl-37439511
4.
Angiogenin is translocated to the nucleus of HeLa cells and is involved in ribosomal RNA transcription and cell proliferation.
Cancer Res
; 65(4): 1352-60, 2005 Feb 15.
Artigo
Inglês
| MEDLINE | ID: mdl-15735021
5.
Endogenous angiogenin in endothelial cells is a general requirement for cell proliferation and angiogenesis.
Oncogene
; 24(3): 445-56, 2005 Jan 13.
Artigo
Inglês
| MEDLINE | ID: mdl-15558023
6.
Neamine inhibits xenografic human tumor growth and angiogenesis in athymic mice.
Clin Cancer Res
; 11(24 Pt 1): 8745-52, 2005 Dec 15.
Artigo
Inglês
| MEDLINE | ID: mdl-16361562
7.
The crystal structure of human angiogenin in complex with an antitumor neutralizing antibody.
Structure
; 11(7): 875-85, 2003 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-12842050
8.
Inhibition of prostate carcinoma establishment and metastatic growth in mice by an antiangiogenin monoclonal antibody.
Int J Cancer
; 98(6): 923-9, 2002 Apr 20.
Artigo
Inglês
| MEDLINE | ID: mdl-11948474
9.
A small-molecule inhibitor of the ribonucleolytic activity of human angiogenin that possesses antitumor activity.
Proc Natl Acad Sci U S A
; 99(15): 10066-71, 2002 Jul 23.
Artigo
Inglês
| MEDLINE | ID: mdl-12118120