Detalhe da pesquisa
1.
Targeting the ERG oncogene with splice-switching oligonucleotides as a novel therapeutic strategy in prostate cancer.
Br J Cancer
; 123(6): 1024-1032, 2020 09.
Artigo
Inglês
| MEDLINE | ID: mdl-32581342
2.
Pharmacology of Modulators of Alternative Splicing.
Pharmacol Rev
; 69(1): 63-79, 2017 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-28034912
3.
Alternative Splicing in Angiogenesis.
Int J Mol Sci
; 20(9)2019 Apr 26.
Artigo
Inglês
| MEDLINE | ID: mdl-31027366
4.
Targeting Angiogenesis in Prostate Cancer.
Int J Mol Sci
; 20(11)2019 May 31.
Artigo
Inglês
| MEDLINE | ID: mdl-31151317
5.
The many faces of SRPK1.
J Pathol
; 241(4): 437-440, 2017 03.
Artigo
Inglês
| MEDLINE | ID: mdl-27859253
6.
Differential Expression of VEGF-Axxx Isoforms Is Critical for Development of Pulmonary Fibrosis.
Am J Respir Crit Care Med
; 196(4): 479-493, 2017 08 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28661183
7.
VEGF-A165 b protects against proteinuria in a mouse model with progressive depletion of all endogenous VEGF-A splice isoforms from the kidney.
J Physiol
; 595(19): 6281-6298, 2017 10 01.
Artigo
Inglês
| MEDLINE | ID: mdl-28574576
8.
Alternative Splicing in CKD.
J Am Soc Nephrol
; 27(6): 1596-603, 2016 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-26763787
9.
SRPK1 inhibition in prostate cancer: A novel anti-angiogenic treatment through modulation of VEGF alternative splicing.
Pharmacol Res
; 107: 276-281, 2016 05.
Artigo
Inglês
| MEDLINE | ID: mdl-26995304
10.
Vascular Endothelial Growth Factor-A165b Is Protective and Restores Endothelial Glycocalyx in Diabetic Nephropathy.
J Am Soc Nephrol
; 26(8): 1889-904, 2015 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-25542969
11.
Regulation of Epithelial-Mesenchymal Transitions by Alternative Splicing: Potential New Area for Cancer Therapeutics.
Genes (Basel)
; 14(11)2023 Oct 26.
Artigo
Inglês
| MEDLINE | ID: mdl-38002944
12.
Detection of genomic mutations in blood and urine free circulating tumour DNA in patients with inoperable and metastatic lung adenocarcinoma harbouring an EGFR mutation in tissue: a UK pilot study.
Front Oncol
; 13: 1197037, 2023.
Artigo
Inglês
| MEDLINE | ID: mdl-37476385
13.
VEGF165b overexpression restores normal glomerular water permeability in VEGF164-overexpressing adult mice.
Am J Physiol Renal Physiol
; 303(7): F1026-36, 2012 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-22811490
14.
SRPK1 inhibition in vivo: modulation of VEGF splicing and potential treatment for multiple diseases.
Biochem Soc Trans
; 40(4): 831-5, 2012 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-22817743
15.
A repositioning screen using an FGFR2 splicing reporter reveals compounds that regulate epithelial-mesenchymal transitions and inhibit growth of prostate cancer xenografts.
Mol Ther Methods Clin Dev
; 25: 147-157, 2022 Jun 09.
Artigo
Inglês
| MEDLINE | ID: mdl-35402635
16.
The epithelial splicing regulator ESRP2 is epigenetically repressed by DNA hypermethylation in Wilms tumour and acts as a tumour suppressor.
Mol Oncol
; 16(3): 630-647, 2022 02.
Artigo
Inglês
| MEDLINE | ID: mdl-34520622
17.
Overexpression of VEGF165b in podocytes reduces glomerular permeability.
J Am Soc Nephrol
; 21(9): 1498-509, 2010 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-20688932
18.
A drug-repositioning screen using splicing-sensitive fluorescent reporters identifies novel modulators of VEGF-A splicing with anti-angiogenic properties.
Oncogenesis
; 10(5): 36, 2021 May 03.
Artigo
Inglês
| MEDLINE | ID: mdl-33941763
19.
CDC2-like (CLK) protein kinase inhibition as a novel targeted therapeutic strategy in prostate cancer.
Sci Rep
; 11(1): 7963, 2021 04 12.
Artigo
Inglês
| MEDLINE | ID: mdl-33846420
20.
A Runaway PRH/HHEX-Notch3-Positive Feedback Loop Drives Cholangiocarcinoma and Determines Response to CDK4/6 Inhibition.
Cancer Res
; 80(4): 757-770, 2020 02 15.
Artigo
Inglês
| MEDLINE | ID: mdl-31843982