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1.
Am J Emerg Med ; 81: 105-110, 2024 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-38733662

RESUMO

INTRODUCTION: Prehospital trauma triage and disability assessment of pediatric patients can be challenging on the field, especially in the pre-verbal age group. It would be useful if the same triage tool and criteria can be used for both adults and children to risk-stratify the need of higher acuity of trauma care. STUDY OBJECTIVE: We aimed to investigate if using only the motor component of Glasgow Coma Scale (mGCS), as a quick field trauma triage tool, was non-inferior to total GCS (tGCS), and if mGCS <6 was non-inferior to tGCS <14, in predicting the need for intensive care or mortality in the pediatric population. METHODS: We performed a retrospective review of patients <18-years-old, who presented to our emergency department (ED) with moderate (Injury Severity Score (ISS) 9-15) to severe (ISS > 15) traumatic injuries from January 2012 to December 2021. Using ED triage data, mortality and the need for intensive care unit (ICU) admission were used as surrogate outcomes to investigate if mGCS <6 was non-inferior to tGCS <14, and the area-under-the-receiver-operating-characteristic curve (AUROC) was used as a measure of comparability. RESULTS: Among 582 included for analysis, the median age was 7-years-old (2-12), and most were male (63.4%). 22.4% patients demised or required ICU care. mGCS <6 had an AUROC of 0.75 (95% CI 0.70 to 0.79), which was non-inferior to tGCS <14; AUROC 0.76, (95% CI 0.72 to 0.81), for identifying children requiring ICU management or demised. The results shown here were based on the AUROCs that were used to evaluate the discriminatory ability of tGCS <14 and mGCS <6 in prediction of mortality and the need for ICU care. CONCLUSION: Our study showed that mGCS was significantly associated with tGCS, and was non- inferior to the latter as a triage tool in pediatric trauma. It validated the use of mGCS <6 in lieu of tGCS <14 in the pre-hospital field triage of pediatric patients, in identification of children at risk of death or requiring ICU care. Larger prospective, observational studies using on-scene data would be required for more robust validation and determine optimal cut-offs.


Assuntos
Serviço Hospitalar de Emergência , Escala de Coma de Glasgow , Triagem , Humanos , Triagem/métodos , Masculino , Feminino , Estudos Retrospectivos , Pré-Escolar , Criança , Adolescente , Escala de Gravidade do Ferimento , Ferimentos e Lesões/mortalidade , Ferimentos e Lesões/diagnóstico , Lactente , Curva ROC , Unidades de Terapia Intensiva
2.
BMC Pediatr ; 22(1): 188, 2022 04 08.
Artigo em Inglês | MEDLINE | ID: mdl-35395789

RESUMO

BACKGROUND: Febrile infants ≤ 90 days old make up a significant proportion of patients seeking care in the emergency department (ED). These infants are vulnerable to serious bacterial infections (SBIs) and early identification is required to initiate timely investigations and interventions. We aimed to study if height of an infant's temperature on presentation to the ED is associated with SBI. METHODS: We performed a retrospective chart review on febrile infants ≤ 90 days old presenting to our ED between 31st March 2015 and 28th February 2016. We compared triage temperature of febrile infants with and without SBIs. We presented sensitivity, specificity, positive and negative predictive values (PPV and NPV) of fever thresholds at triage. A multivariable regression was performed to study the association between height of temperature and the presence of SBI, and presented the adjusted odds ratio (aOR) with corresponding 95% confidence intervals (CI). RESULTS: Among 1057 febrile infants analysed, 207 (19.6%) had a SBI. Mean temperature of infants with a SBI was significantly higher than those without (mean 38.5 °C, standard deviation, SD 0.6 vs. 38.3 °C, SD 0.5, p < 0.005). For temperature ≥ 39 °C, sensitivity, specificity, PPV and NPV for SBI was 15.5% (95%CI 10.8-21.1%), 90.4% (95%CI 88.2-92.3%), 28.1% (95%CI 21.1-36.3%) and 81.4% (95%CI 80.5-82.4%) respectively. The height of fever was consistently associated with SBI after adjusting for age, gender and SIS (aOR 1.76, 95% CI 1.32-2.33, p < 0.001). However, 32 (15.5%) infants with SBIs had an initial triage temperature ≤ 38 °C. CONCLUSIONS: A higher temperature at triage was associated with a higher risk of SBI among febrile infants ≤ 90 days old. However, height of temperature must be used in conjunction with other risk factors to identify SBIs in young infants.


Assuntos
Infecções Bacterianas , Infecções Urinárias , Infecções Bacterianas/complicações , Infecções Bacterianas/diagnóstico , Infecções Bacterianas/microbiologia , Febre/microbiologia , Humanos , Lactente , Estudos Retrospectivos , Triagem , Infecções Urinárias/microbiologia
3.
Emerg Med J ; 39(7): 527-533, 2022 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-34344733

RESUMO

INTRODUCTION: Initial low systolic blood pressure (SBP) in paediatric traumatic brain injury (TBI) is associated with mortality. There is limited literature on how other haemodynamic parameters including heart rate (HR); diastolic blood pressure (DBP); mean arterial pressure (MAP); and shock index, paediatric age-adjusted (SIPA) affect not only mortality but also long-term neurological outcomes in paediatric TBI. We aimed to analyse the associations of these haemodynamic variables (HR, SBP, MAP, DBP and SIPA) with mortality and long-term neurological outcomes in isolated moderate-to-severe paediatric TBI. METHODS: This was a secondary analysis of our primary study that analysed the association of TBI-associated coagulopathy with mortality and neurological outcome in isolated, moderate-to-severe paediatric head injury. A trauma registry-based, retrospective study of children <18 years old who presented to the emergency department with isolated, moderate-to-severe TBI from January 2010 to December 2016 was conducted. The association between initial haemodynamic variables and less favourable outcomes using Glasgow Outcome Scale-Extended Paediatric) at 6 months post injury was analysed using logistic regression. RESULTS: Among 152 children analysed, initial systolic and diastolic hypotension (<5th percentile) (OR) for SBP 11.40, 95% CI 3.60 to 36.05, p<0.001; OR for DBP 15.75, 95% CI 3.09 to 80.21, p<0.001) and Glasgow Coma Scale scores <8 (OR 14.50, 95% CI 3.65 to 57.55, p<0.001) were associated with 'moderate-to-severe neurological disabilities', 'vegetative state' and 'death'. After adjusting for confounders, only SBP was significant (adjusted OR 5.68, 95% CI 1.40 to 23.08, p=0.015). CONCLUSIONS: Initial systolic hypotension was independently associated with mortality and moderate-to-severe neurological deficits at 6 months post injury. Further work is required to understand if early correction of hypotension will improve long-term outcomes.


Assuntos
Lesões Encefálicas Traumáticas , Hipotensão , Choque , Adolescente , Pressão Sanguínea/fisiologia , Lesões Encefálicas Traumáticas/complicações , Criança , Escala de Coma de Glasgow , Humanos , Hipotensão/complicações , Estudos Retrospectivos
4.
Pediatr Emerg Care ; 38(4): 183-186, 2022 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-34608058

RESUMO

ABSTRACT: Abdominal pain is one of the most common presenting complaints encountered in the pediatric emergency department. The use of point-of-care ultrasonography by emergency physicians has been shown to expedite the diagnosis of a large variety of conditions and can be used to accurately identify intra-abdominal pathology in children. We describe the case of a pediatric patient who presented to the pediatric emergency department with acute abdominal pain, in whom point-of-care ultrasonography helped expedite the diagnosis of acute portal vein thrombosis and liver abscess.


Assuntos
Sistemas Automatizados de Assistência Junto ao Leito , Trombose Venosa , Criança , Humanos , Testes Imediatos , Veia Porta/diagnóstico por imagem , Ultrassonografia , Trombose Venosa/diagnóstico por imagem
5.
Pediatr Emerg Care ; 38(12): 672-677, 2022 Dec 01.
Artigo em Inglês | MEDLINE | ID: mdl-36449737

RESUMO

OBJECTIVES: Pediatric ankle injuries remain one of the most common presenting complaints to the pediatric emergency department (PED). In this study, we aimed to describe risk factors associated with simple ankle fractures and ankle fractures that require surgery, among adolescents presenting to the PED with ankle injuries. METHODS: We analyzed a retrospective cohort study of adolescents 12 to 16 years old who presented to our PED with an acute ankle injury and received an ankle radiograph from November 1, 2016, to October 31, 2017. Demographic, anthropometric variables, physical examination findings including those of the Ottawa Ankle Rules were obtained. We recorded any surgical interventions required, as well as follow-up and to return to physical activity. RESULTS: Five hundred fifty-six cases of adolescent ankle injuries were reviewed, of which 109 adolescents had ankle fractures, whereas 19 had ankle fractures requiring surgery. Sports-related injuries remained the most common cause of ankle fractures. Age (adjusted odds ratio [aOR], 0.69; 95% confidence interval [CI], 0.56-0.83; P < 0.001), male sex (aOR, 2.12; 95% CI, 1.34-3.35; P < 0.001), clinical findings of tenderness over the lateral malleolus (aOR, 3.13; 95% CI, 1.74-5.64; P < 0.001) or medial malleolus (aOR, 3.55; 95% CI, 2.18-5.78; P < 0.001), and inability to walk (aOR, 3.09; 95% CI, 1.95-4.91; P < 0.001) were significant independent risk factors for ankle fractures.Patients with a weight more than 90th centile for age were at greater risk of ankle fractures requiring surgery (aOR, 2.64; 95% CI, 1.05-6.64; P = 0.04). CONCLUSIONS: We found that younger age, male sex, and clinical findings in the Ottawa Ankle Rules correlated well with predicting ankle fractures and are well suited for application in the Southeast Asian population. Weight greater than the 90th percentile for age was a significant risk factor for ankle fractures requiring surgery.


Assuntos
Fraturas do Tornozelo , Traumatismos do Tornozelo , Adolescente , Humanos , Masculino , Criança , Tornozelo , Fraturas do Tornozelo/epidemiologia , Traumatismos do Tornozelo/epidemiologia , Traumatismos do Tornozelo/cirurgia , Estudos Retrospectivos , Fatores de Risco , Serviço Hospitalar de Emergência
6.
Emerg Med J ; 38(8): 607-612, 2021 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-33863774

RESUMO

BACKGROUND: Early differentiation of febrile young infants with from those without serious infections (SIs) remains a diagnostic challenge. We sought to (1) compare vital signs and heart rate variability (HRV) parameters between febrile infants with versus without SIs, (2) assess the performance of HRV and vital signs with reference to current triage tools and (3) compare HRV and vital signs to HRV, vital signs and blood biomarkers, when predicting for the presence of SIs. METHODS: Using a prospective observational design, we recruited patients <3 months old presenting to a tertiary paediatric ED in Singapore from December 2018 through November 2019. We obtained patient demographic characteristics, triage assessment (including the Severity Index Score (SIS)), HRV parameters (time, frequency and non-linear domains) and laboratory results. We performed multivariable logistic regression analyses to predict the presence of an SI, using area under the curve (AUC) with the corresponding 95% CI to assess predictive capability. RESULTS: Among 203 infants with a mean age of 38.4 days (SD 27.6), 67 infants (33.0%) had an SI. There were significant differences in the time, frequency and non-linear domains of HRV parameters between infants with versus without SIs. In predicting SIs, gender, temperature and the HRV non-linear parameter Poincaré plot SD2 (AUC 0.78, 95% CI 0.71 to 0.84) performed better than SIS alone (AUC 0.61, 95% CI 0.53 to 0.68). Model performance improved with the addition of absolute neutrophil count and C reactive protein (AUC 0.82, 95% CI 0.76 to 0.89). CONCLUSION: An exploratory prediction model incorporating HRV and biomarkers improved prediction of SIs. Further research is needed to assess if HRV can identify which young febrile infants have an SI at ED triage. TRIAL REGISTRATION NUMBER: NCT04103151.


Assuntos
Biomarcadores/sangue , Serviço Hospitalar de Emergência , Frequência Cardíaca , Infecções/diagnóstico , Diagnóstico Precoce , Feminino , Febre , Humanos , Lactente , Masculino , Projetos Piloto , Valor Preditivo dos Testes , Estudos Prospectivos , Índice de Gravidade de Doença , Singapura , Sinais Vitais
7.
Pediatr Emerg Care ; 37(4): 226-229, 2021 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-33780407

RESUMO

BACKGROUND: Tuberculosis of the abdomen is one of the most common extrapulmonary manifestations of tuberculosis. Even in areas where tuberculosis is endemic, intra-abdominal tuberculous can pose a diagnostic and management challenge because of the lack of presence of overt clinical signs and availability of expertise for point of care diagnostics. Point-of-care ultrasound (POCUS) of the abdomen performed by emergency physicians is increasingly being used for a variety of clinical presentations to facilitate accurate diagnoses in the emergency department. CASE REPORT: We describe the case of a patient presenting to the pediatric emergency department with acute abdominal pain, in whom POCUS helped expedite the diagnosis of abdominal tuberculosis. CONCLUSIONS: In the right clinical setting, the concurrent presence of intra-abdominal lymphadenopathy, ascites, mesenteric thickening, ileocecal thickening, and splenic microabscesses on ultrasound imaging should lead to consideration of the diagnosis of intra-abdominal tuberculosis. Although typically diagnosed on computed tomography or magnetic resonance imaging, in our case, POCUS helped facilitate the bedside diagnosis of abdominal tuberculosis in the emergency department.


Assuntos
Linfadenopatia , Tuberculose , Abdome/diagnóstico por imagem , Criança , Humanos , Linfonodos/diagnóstico por imagem , Sistemas Automatizados de Assistência Junto ao Leito , Testes Imediatos , Tuberculose/diagnóstico por imagem , Ultrassonografia
8.
J Emerg Med ; 58(4): 632-635, 2020 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-32204994

RESUMO

BACKGROUND: Eye examination in distressed young children can be challenging in a busy emergency department. A full, detailed evaluation is, however, often needed in ocular emergencies. CASE REPORT: A 2-year-old boy presented to our pediatric emergency department with refusal to open his left eye for 1 day. Eye examination was difficult and yielded limited findings, despite analgesia and parental facilitation. Under such circumstances, this might require sedation or forcibly everting the child's eyelids for the eye evaluation. A rapid ocular point-of-care ultrasound was performed, which revealed sonographic findings suggestive of a retinoblastoma in the left eye. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: The use of ocular point-of-care ultrasound facilitated the diagnosis of retinoblastoma in a child who was highly distressed and difficult to examine. Its use under such circumstances facilitated the patient's prompt evaluation and subsequent management.


Assuntos
Neoplasias da Retina , Retinoblastoma , Pré-Escolar , Serviço Hospitalar de Emergência , Humanos , Masculino , Sistemas Automatizados de Assistência Junto ao Leito , Neoplasias da Retina/diagnóstico por imagem , Retinoblastoma/diagnóstico por imagem , Ultrassonografia
9.
J Emerg Med ; 59(1): 75-83, 2020 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-32354589

RESUMO

BACKGROUND: Children present to the pediatric emergency department (ED) with enlarged lymph nodes due to a broad spectrum of conditions ranging from benign causes like reactive lymph nodes to adverse conditions like malignancy. Identifying sonographic features typical of infection, inflammation, and neoplasms will help assist clinicians in deciding the disposition of the patients from the ED. Point-of-care ultrasound has become an essential adjunct for diagnostic assessment in pediatric emergency medicine. The wider accessibility of ultrasound along with greater resolution using high-frequency probes places this noninvasive, nonradiation-based bedside examination, an ideal tool for real-time examination of the lymph nodes in the EDs. CASE SERIES: We present a series of cases in which the point-of-care ultrasound examination proved valuable in the timely diagnosis and expedited care of lymph node pathologies secondary to reactive, infectious, and malignant processes. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: Point-of-care ultrasound will facilitate diagnosis in children with lymph node swelling and should be considered in children of all ages. While assessing the lymph node pathology at the bedside, describe the shape, size, internal echotexture, borders, vascularity, and the pattern of the perinodal soft tissue to differentiate between a normal, reactive, infectious, inflammatory, or malignant underlying pathology.


Assuntos
Linfadenopatia , Sistemas Automatizados de Assistência Junto ao Leito , Criança , Serviço Hospitalar de Emergência , Humanos , Linfonodos/diagnóstico por imagem , Linfadenopatia/diagnóstico por imagem , Ultrassonografia
10.
Emerg Med J ; 37(5): 252-254, 2020 May.
Artigo em Inglês | MEDLINE | ID: mdl-32321705

RESUMO

Singapore was one of the earliest countries affected by the coronavirus disease 2019 (COVID-19) pandemic, with more laboratory-confirmed COVID-19 cases in early February 2020 than any other country outside China. This short report is a narrative review of our tertiary paediatric emergency department (ED) perspective and experience managing the evolving outbreak situation. Logistic considerations included the segregation of the ED into physically separate high-risk, intermediate-risk and low-risk areas, with risk-adapted use of personal protective equipment (PPE) for healthcare personnel in each ED area. Workflow considerations included the progressive introduction of outpatient COVID-19 testing in the ED for enhanced surveillance; adapting the admissions process particularly for high-risk and intermediate-risk cases; and the management of unwell accompanying adult caregivers. Manpower considerations included the reorganisation of medical manpower into modular teams to mitigate the risk of hospital transmission of COVID-19. Future plans for a tiered isolation facility should include structural modifications for the permanent isolation facility such as anterooms for PPE donning/doffing; replication of key ED functions in the tent facility such as a separate resuscitation room and portable X-ray room; and refresher PPE training. Dynamic reassessment of ED workflow processes, in conjunction with the hospital and national public health response, may help in managing this novel disease entity.


Assuntos
Infecções por Coronavirus , Coronavirus , Serviço Hospitalar de Emergência/organização & administração , Pandemias/prevenção & controle , Pneumonia Viral , Betacoronavirus , COVID-19 , Teste para COVID-19 , Criança , Técnicas de Laboratório Clínico , Infecções por Coronavirus/diagnóstico , Infecções por Coronavirus/epidemiologia , Infecções por Coronavirus/prevenção & controle , Infecções por Coronavirus/terapia , Surtos de Doenças/prevenção & controle , Pessoal de Saúde , Humanos , Equipamento de Proteção Individual , Pneumonia Viral/diagnóstico , Pneumonia Viral/epidemiologia , Pneumonia Viral/prevenção & controle , Pneumonia Viral/terapia , Guias de Prática Clínica como Assunto , Saúde Pública , SARS-CoV-2 , Singapura/epidemiologia
11.
Circulation ; 138(23): e714-e730, 2018 12 04.
Artigo em Inglês | MEDLINE | ID: mdl-30571263

RESUMO

The International Liaison Committee on Resuscitation has initiated a continuous review of new, peer-reviewed, published cardiopulmonary resuscitation science. This is the second annual summary of International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations that includes the most recent cardiopulmonary resuscitation science reviewed by the International Liaison Committee on Resuscitation. This summary addresses the role of antiarrhythmic drugs in adults and children and includes the Advanced Life Support Task Force and Pediatric Task Force consensus statements, which summarize the most recent published evidence and an assessment of the quality of the evidence based on Grading of Recommendations, Assessment, Development, and Evaluation criteria. The statements include consensus treatment recommendations approved by members of the relevant task forces. Insights into the deliberations of each task force are provided in the Values and Preferences and Task Force Insights sections. Finally, the task force members have listed the top knowledge gaps for further research.


Assuntos
Reanimação Cardiopulmonar , Parada Cardíaca Extra-Hospitalar/terapia , Amiodarona/uso terapêutico , Antiarrítmicos/uso terapêutico , Consenso , Serviços Médicos de Emergência , Humanos , Lidocaína/uso terapêutico , Magnésio/uso terapêutico , Parada Cardíaca Extra-Hospitalar/tratamento farmacológico
12.
J Emerg Med ; 56(4): 417-420, 2019 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-30745196

RESUMO

BACKGROUND: Headache and monocular visual disturbance are worrisome pediatric presenting complaints in the emergency department. Appropriate and timely initial evaluation is critical. Most would opt for urgent computer tomography in such cases. Pediatric optic neuritis is a rare condition and is better evaluated by magnetic resonance imaging. With the increase in the use and scope of bedside ultrasound, there might be a potential role for transorbital ultrasound to be part of the emergency department evaluation of pediatric optic neuritis. CASE REPORT: This is the first pediatric case report on the use of bedside transorbital ultrasound in the emergency department evaluation of a 15-year-old girl with optic neuritis who presented with unilateral headache and left visual disturbance. Transorbital ultrasound of her left eye revealed an irregularly enlarged optic nerve sheath with increased optic nerve sheath diameter (5.1 mm) and an elevated optic disc height (0.5 mm). Ultrasound examination of her right eye was contrastingly normal, showing an optic nerve sheath diameter of 3.8 mm and that the optic disc was not elevated. The ultrasound findings correlated well with her magnetic resonance imaging of her orbits. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: The clinical findings and monocular ultrasound abnormalities facilitated the emergency department decision-making process and choice of neuroimaging. This highlights the use of transorbital ultrasound as a clinical adjunct and potential role in the emergency department clinical evaluation of a pediatric patient with optic neuritis. The finding of an irregularly enlarged optic nerve might be of potential clinical value but further studies are required.


Assuntos
Neurite Óptica/diagnóstico , Órbita/fisiologia , Ultrassonografia/métodos , Adolescente , Serviço Hospitalar de Emergência/organização & administração , Feminino , Cefaleia/etiologia , Humanos , Neurite Óptica/diagnóstico por imagem , Órbita/diagnóstico por imagem , Tomografia Computadorizada por Raios X/métodos
13.
J Emerg Med ; 56(4): 421-425, 2019 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-30638645

RESUMO

BACKGROUND: Point-of-care ultrasonography (POCUS) is increasingly used for both diagnostic and guided procedures. Increasingly, POCUS has been used for identification of pneumonia and to assist in the differentiation of pleural effusions, as well as to guide thoracentesis. As such, there is a need for training with ideally high-fidelity lung ultrasound phantoms to ensure ultrasound proficiency and procedural competency. Unfortunately, most commercial ultrasound phantoms remain expensive and may have limited fidelity. OBJECTIVE: Our aim was to create and describe a homemade, high-fidelity ultrasound phantom model for demonstrating pneumonia with pleural effusions for teaching purposes. DISCUSSION: An ultrasound phantom was constructed using a water-filled latex glove with a sliver of meat in it, covered over by a palm-sized piece of meat (skin and ribs are optional to increase ultrasonographic details and realism). This would appear like parapneumonic effusions with organized pneumonia under ultrasound examination. Creamer (or talc) can be added to the water in the glove to simulate empyema. The model can also be used to teach simple effusions and for ultrasound-guided thoracentesis and in clinical decision making. CONCLUSIONS: Easily prepared, homemade high-fidelity ultrasound phantom models for instructions on identification of pleural effusions and ultrasound-guided pleural tap of parapneumonic effusion were made.


Assuntos
Empiema/diagnóstico , Derrame Pleural/diagnóstico , Treinamento por Simulação/métodos , Ultrassonografia/métodos , Humanos , Pneumonia/diagnóstico , Pneumonia/fisiopatologia , Sistemas Automatizados de Assistência Junto ao Leito , Ultrassonografia/instrumentação
15.
Emerg Med J ; 36(12): 729-735, 2019 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-31653694

RESUMO

OBJECTIVE: Febrile infants≤3 months old constitute a vulnerable group at risk of serious infections (SI). We aimed to (1) study the test performance of two clinical assessment tools-the National Institute for Health and Care Excellence (NICE) Traffic Light System and Severity Index Score (SIS) in predicting SI among all febrile young infants and (2) evaluate the performance of three low-risk criteria-the Rochester Criteria (RC), Philadelphia Criteria (PC) and Boston Criteria (BC) among well-looking febrile infants. METHODS: A retrospective validation study was conducted. Serious illness included both bacterial and serious viral illness such as meningitis and encephalitis. We included febrile infants≤3 months old presenting to a paediatric emergency department in Singapore between March 2015 and February 2016. Infants were assigned to high-risk and low-risk groups for SI according to each of the five tools. We compared the performance of the NICE guideline and SIS at initial clinical assessment for all infants and the low-risk criteria-RC, PC and BC-among well-looking infants. We presented their performance using sensitivity, specificity, positive, negative predictive values and likelihood ratios. RESULTS: Of 1057 infants analysed, 326 (30.8%) were diagnosed with SI. The NICE guideline had an overall sensitivity of 93.3% (95% CI 90.0 to 95.7), while the SIS had a sensitivity of 79.1% (95% CI 74.3 to 83.4). The incidence of SI was similar among infants who were well-looking and those who were not. Among the low-risk criteria, the RC performed with the highest sensitivity in infants aged 0-28 days (98.2%, 95% CI 90.3% to 100.0%) and 29-60 days (92.4%, 95% CI 86.0% to 96.5%), while the PC performed best in infants aged 61-90 days (100.0%, 95% CI 95.4% to 100.0%). CONCLUSIONS: The NICE guideline achieved high sensitivity in our study population, and the RC had the highest sensitivity in predicting for SI among well-appearing febrile infants. Prospective validation is required.


Assuntos
Infecções Bacterianas/epidemiologia , Serviço Hospitalar de Emergência/normas , Febre/diagnóstico , Índice de Gravidade de Doença , Viroses/epidemiologia , Infecções Bacterianas/complicações , Infecções Bacterianas/diagnóstico , Feminino , Febre/etiologia , Humanos , Incidência , Lactente , Recém-Nascido , Masculino , Guias de Prática Clínica como Assunto , Valor Preditivo dos Testes , Estudos Retrospectivos , Medição de Risco/métodos , Medição de Risco/normas , Singapura/epidemiologia , Viroses/complicações , Viroses/diagnóstico
16.
Circulation ; 136(23): e424-e440, 2017 12 05.
Artigo em Inglês | MEDLINE | ID: mdl-29114010

RESUMO

The International Liaison Committee on Resuscitation has initiated a near-continuous review of cardiopulmonary resuscitation science that replaces the previous 5-year cyclic batch-and-queue approach process. This is the first of an annual series of International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations summary articles that will include the cardiopulmonary resuscitation science reviewed by the International Liaison Committee on Resuscitation in the previous year. The review this year includes 5 basic life support and 1 pediatric Consensuses on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations. Each of these includes a summary of the science and its quality based on Grading of Recommendations, Assessment, Development, and Evaluation criteria and treatment recommendations. Insights into the deliberations of the International Liaison Committee on Resuscitation task force members are provided in Values and Preferences sections. Finally, the task force members have prioritized and listed the top 3 knowledge gaps for each population, intervention, comparator, and outcome question.


Assuntos
Cardiologia/normas , Reanimação Cardiopulmonar/normas , Serviços Médicos de Emergência/normas , Medicina de Emergência/normas , Medicina Baseada em Evidências/normas , Parada Cardíaca/terapia , Fatores Etários , Consenso , Parada Cardíaca/diagnóstico , Parada Cardíaca/mortalidade , Humanos , Parada Cardíaca Extra-Hospitalar/diagnóstico , Parada Cardíaca Extra-Hospitalar/mortalidade , Parada Cardíaca Extra-Hospitalar/terapia , Resultado do Tratamento
17.
Pediatr Cardiol ; 39(8): 1530-1534, 2018 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-29923133

RESUMO

Troponin I is a cardiac enzyme that is released during myocardial injury. However, cardiac enzymes are non-specific and can occur in many cardiac and non-cardiac pathologies. We aim to (1) describe the range of acute conditions that were associated with raised troponins in the paediatric population in our institution and (2) quantify the extent of troponin elevation and correlate it with the underlying aetiology. We performed a retrospective observational study in a tertiary institution which included patients from 1 January 2009 to 31 December 2013. We identified patients with troponin I levels of more than 0.1 ng/ml who have not had cardiac surgery before. We recorded their final diagnoses, and then compared the peak troponin levels and the eventual final diagnoses. We identified 100 patients. The top few common diagnoses resulting in a raised troponin were sepsis (29%), cardiac pathologies (29%) such as tachyarrhythmias and cardiomyopathies and myocarditis (21%). Other pathologies included trauma and other causes of multiorgan dysfunction. The median peak troponin I was higher in cardiac as compared to non-cardiac pathologies: 2.15 (0.52-15.0) and 0.44 (0.21-1.68), respectively. There was no statistically significant difference in the peak troponin I values in the presence of hypotension or renal impairment. We described the range of conditions that may result in raised troponin I levels. The extent of raised troponin I levels may potentially be useful in differentiating between cardiac and non-cardiac pathologies. However, further studies on a larger scale are required to establish whether extent of troponin I elevation has a diagnostic role for cardiac pathologies.


Assuntos
Biomarcadores/sangue , Cardiopatias/sangue , Troponina I/sangue , Doença Aguda/epidemiologia , Criança , Pré-Escolar , Feminino , Cardiopatias/epidemiologia , Humanos , Lactente , Masculino , Estudos Retrospectivos , Sepse/sangue , Sepse/epidemiologia
18.
J Emerg Med ; 55(6): 813-816, 2018 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-30253955

RESUMO

BACKGROUND: Orbital cellulitis is an uncommon ophthalmological emergency in children, but rapid emergency department (ED) diagnosis is essential. CASE REPORT: A 13-year-old boy presented to our pediatric ED with left orbital cellulitis secondary to pansinusitis. Emergency bedside ocular ultrasonography was used to evaluate and expedite his management. Besides inflammatory changes observed on ultrasound of his affected orbit, the patient had an elevated optic disc height and increased nerve sheath diameter, which were not commonly reported in published literature on orbital cellulitis. Emergent computed tomography of the orbits and head showed orbital cellulitis without complications of orbital abscess or cavernous sinus thrombosis. Despite initiating early appropriate antibiotics, there was rapid progression of his disease and he developed intraconal abscess and cavernous sinus thrombosis the following day. After emergency surgical drainage of his pansinusitis, antibiotics, and anticoagulation, he was discharged well after a 2-week hospitalization. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: There are important advantages of using bedside ultrasonography for diagnosis of pediatric orbital cellulitis in the ED setting. Further research should be done to evaluate the clinical significance of an enlarged optic nerve sheath diameter and raised optic disc height in pediatric orbital cellulitis.


Assuntos
Disco Óptico/diagnóstico por imagem , Nervo Óptico/diagnóstico por imagem , Celulite Orbitária/diagnóstico por imagem , Celulite Orbitária/terapia , Ultrassonografia/métodos , Adolescente , Terapia Combinada , Humanos , Masculino , Disco Óptico/patologia , Nervo Óptico/patologia , Celulite Orbitária/patologia , Tomografia Computadorizada por Raios X
19.
Pediatr Emerg Care ; 34(12): 852-856, 2018 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-29166296

RESUMO

INTRODUCTION: Resuscitation of critically ill children can be chaotic, and emergency airway management is often fraught with difficulties. This study aimed to characterize the Singaporean landscape of tracheal intubation in a pediatric emergency unit, placing emphasis on safety outcomes, procedural process of care, and provider training. METHODS: A retrospective review of all cases presented to the KK Women's and Children's Hospital from January 2009 to December 2013 with intubation carried out within the pediatric emergency unit was done. Medical records were accessed for data collection, and the information was subsequently used for analysis. RESULTS: A total of 207 intubations were carried out in the pediatric emergency unit. The median age was 4 years (interquartile range, 11 months to 8 years). Oral tracheal intubation with the combination of sedation and paralysis was the main approach. Atropine was used for pretreatment in 156 cases (75.4%). Midazolam was the most commonly used induction agent, and succinylcholine was the most commonly used the paralytic agent. Intubation was achieved on the first attempt in 175 cases (84.5%). Postintubation sedation was initiated in 94 cases (45.4%). Postintubation paralysis was initiated in 50 cases (24.2%). Postintubation analgesia was initiated in 13 cases (6.3%). Twenty emergency intubations (9.7%) were associated with at least 1 tracheal intubation adverse event, with 7 cases (3.4%) having severe tracheal intubation adverse events. In 1 case (0.5%), the patient died within the pediatric emergency unit, and 27 patients (13.0%) did not survive to discharge from the hospital. CONCLUSIONS: All tracheal intubations performed were successful. Variance still exists in tracheal intubation practice. Further elucidation of patient, practice, and provider factors will aid development of a bundle quality improvement intervention directed at addressing these factors.


Assuntos
Serviço Hospitalar de Emergência/estatística & dados numéricos , Hospitais com Alto Volume de Atendimentos/estatística & dados numéricos , Intubação Intratraqueal/estatística & dados numéricos , Padrões de Prática Médica/estatística & dados numéricos , Criança , Pré-Escolar , Estado Terminal/terapia , Feminino , Humanos , Lactente , Intubação Intratraqueal/efeitos adversos , Intubação Intratraqueal/mortalidade , Masculino , Estudos Retrospectivos , Singapura , Taxa de Sobrevida
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