1.
Chem Commun (Camb)
; 49(95): 11188-90, 2013 Dec 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-24150718
RESUMO
Stabilized Wittig olefination holds great potential as a bioconjugation reaction. We demonstrate that the reaction of stabilized phosphorus ylides (or phosphonium salts) with aryl aldehydes is sufficiently robust to be used for live cell affinity isolation and fluorescence tagging of a protein, FKBP12.