Detalhe da pesquisa
1.
Hepatic Pin1 Expression, Particularly in Nuclei, Is Increased in NASH Patients in Accordance with Evidence of the Role of Pin1 in Lipid Accumulation Shown in Hepatoma Cell Lines.
Int J Mol Sci
; 24(10)2023 May 16.
Artigo
Inglês
| MEDLINE | ID: mdl-37240193
2.
Auraptene Enhances AMP-Activated Protein Kinase Phosphorylation and Thereby Inhibits the Proliferation, Migration and Expression of Androgen Receptors and Prostate-Specific Antigens in Prostate Cancer Cells.
Int J Mol Sci
; 24(21)2023 Nov 06.
Artigo
Inglês
| MEDLINE | ID: mdl-37958994
3.
Separation of the gluconeogenic and mitochondrial functions of PGC-1{alpha} through S6 kinase.
Genes Dev
; 25(12): 1232-44, 2011 Jun 15.
Artigo
Inglês
| MEDLINE | ID: mdl-21646374
4.
Molecular Mechanisms of Hypothalamic Insulin Resistance.
Int J Mol Sci
; 20(6)2019 Mar 15.
Artigo
Inglês
| MEDLINE | ID: mdl-30875909
5.
Xanthine Oxidase Inhibitor Febuxostat Exerts an Anti-Inflammatory Action and Protects against Diabetic Nephropathy Development in KK-Ay Obese Diabetic Mice.
Int J Mol Sci
; 20(19)2019 Sep 21.
Artigo
Inglês
| MEDLINE | ID: mdl-31546603
6.
The prolyl isomerase Pin1 increases ß-cell proliferation and enhances insulin secretion.
J Biol Chem
; 292(28): 11886-11895, 2017 07 14.
Artigo
Inglês
| MEDLINE | ID: mdl-28566287
7.
The Xanthine Oxidase Inhibitor Febuxostat Suppresses the Progression of IgA Nephropathy, Possibly via Its Anti-Inflammatory and Anti-Fibrotic Effects in the gddY Mouse Model.
Int J Mol Sci
; 19(12)2018 Dec 10.
Artigo
Inglês
| MEDLINE | ID: mdl-30544662
8.
The SGLT2 Inhibitor Luseogliflozin Rapidly Normalizes Aortic mRNA Levels of Inflammation-Related but Not Lipid-Metabolism-Related Genes and Suppresses Atherosclerosis in Diabetic ApoE KO Mice.
Int J Mol Sci
; 18(8)2017 Aug 04.
Artigo
Inglês
| MEDLINE | ID: mdl-28777298
9.
Prolyl isomerase Pin1 negatively regulates AMP-activated protein kinase (AMPK) by associating with the CBS domain in the γ subunit.
J Biol Chem
; 290(40): 24255-66, 2015 Oct 02.
Artigo
Inglês
| MEDLINE | ID: mdl-26276391
10.
Role of Uric Acid Metabolism-Related Inflammation in the Pathogenesis of Metabolic Syndrome Components Such as Atherosclerosis and Nonalcoholic Steatohepatitis.
Mediators Inflamm
; 2016: 8603164, 2016.
Artigo
Inglês
| MEDLINE | ID: mdl-28070145
11.
Physiological and Pathogenic Roles of Prolyl Isomerase Pin1 in Metabolic Regulations via Multiple Signal Transduction Pathway Modulations.
Int J Mol Sci
; 17(9)2016 Sep 07.
Artigo
Inglês
| MEDLINE | ID: mdl-27618008
12.
Mediobasal hypothalamic PTEN modulates hepatic insulin resistance independently of food intake in rats.
Am J Physiol Endocrinol Metab
; 307(1): E47-60, 2014 Jul 01.
Artigo
Inglês
| MEDLINE | ID: mdl-24824654
13.
Trk-fused gene plays a critical role in diet-induced adipose tissue expansion and is also involved in thyroid hormone action.
PNAS Nexus
; 3(4): pgae150, 2024 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-38681675
14.
Insulin Sensitivity Initially Worsens but Later Improves With Aging in Male C57BL/6N Mice.
J Gerontol A Biol Sci Med Sci
; 78(10): 1785-1792, 2023 Oct 09.
Artigo
Inglês
| MEDLINE | ID: mdl-37205871
15.
Peptidyl-prolyl cis/trans isomerase NIMA-interacting 1 associates with insulin receptor substrate-1 and enhances insulin actions and adipogenesis.
J Biol Chem
; 286(23): 20812-22, 2011 Jun 10.
Artigo
Inglês
| MEDLINE | ID: mdl-21454638
16.
Hypoglycemic effects of colestimide on type 2 diabetic patients with obesity.
Endocr J
; 59(3): 239-46, 2012.
Artigo
Inglês
| MEDLINE | ID: mdl-22230809
17.
Involvement of neuronal and muscular Trk-fused gene (TFG) defects in the development of neurodegenerative diseases.
Sci Rep
; 12(1): 1966, 2022 02 04.
Artigo
Inglês
| MEDLINE | ID: mdl-35121777
18.
4F2hc stabilizes GLUT1 protein and increases glucose transport activity.
Am J Physiol Cell Physiol
; 300(5): C1047-54, 2011 May.
Artigo
Inglês
| MEDLINE | ID: mdl-21270293
19.
Pin1 associates with and induces translocation of CRTC2 to the cytosol, thereby suppressing cAMP-responsive element transcriptional activity.
J Biol Chem
; 285(43): 33018-33027, 2010 Oct 22.
Artigo
Inglês
| MEDLINE | ID: mdl-20675384
20.
Activation of hypothalamic S6 kinase mediates diet-induced hepatic insulin resistance in rats.
J Clin Invest
; 118(8): 2959-68, 2008 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-18618016