Detalhe da pesquisa
1.
G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling.
Cell
; 184(3): 655-674.e27, 2021 02 04.
Artigo
Inglês
| MEDLINE | ID: mdl-33497611
2.
IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression.
Cell
; 182(5): 1252-1270.e34, 2020 09 03.
Artigo
Inglês
| MEDLINE | ID: mdl-32818467
3.
cDC1 to cDC2: "Everything I do, Ido1 it for you".
Immunity
; 55(6): 967-970, 2022 06 14.
Artigo
Inglês
| MEDLINE | ID: mdl-35704997
4.
Making liver cancer cells go ARGh!
EMBO J
; 41(21): e112415, 2022 11 02.
Artigo
Inglês
| MEDLINE | ID: mdl-36222348
5.
ID3 promotes homologous recombination via non-transcriptional and transcriptional mechanisms and its loss confers sensitivity to PARP inhibition.
Nucleic Acids Res
; 49(20): 11666-11689, 2021 11 18.
Artigo
Inglês
| MEDLINE | ID: mdl-34718742
6.
Comparative Assessment of Quantification Methods for Tumor Tissue Phosphoproteomics.
Anal Chem
; 94(31): 10893-10906, 2022 08 09.
Artigo
Inglês
| MEDLINE | ID: mdl-35880733
7.
Hepatocyte-intrinsic type I interferon signaling reprograms metabolism and reveals a novel compensatory mechanism of the tryptophan-kynurenine pathway in viral hepatitis.
PLoS Pathog
; 16(10): e1008973, 2020 10.
Artigo
Inglês
| MEDLINE | ID: mdl-33045014
8.
The therapeutic potential of targeting tryptophan catabolism in cancer.
Br J Cancer
; 122(1): 30-44, 2020 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31819194
9.
Hypoxia decreases the T helper cell-suppressive capacity of synovial fibroblasts by downregulating IDO1-mediated tryptophan metabolism.
Rheumatology (Oxford)
; 59(5): 1148-1158, 2020 05 01.
Artigo
Inglês
| MEDLINE | ID: mdl-31846032
10.
Synovial Fibroblasts Selectively Suppress Th1 Cell Responses through IDO1-Mediated Tryptophan Catabolism.
J Immunol
; 198(8): 3109-3117, 2017 04 15.
Artigo
Inglês
| MEDLINE | ID: mdl-28264972
11.
Quantitative Analysis of Proteome Modulations in Alveolar Epithelial Type II Cells in Response to Pulmonary Aspergillus fumigatus Infection.
Mol Cell Proteomics
; 16(12): 2184-2198, 2017 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-28951444
12.
Suppression of Th1 differentiation by tryptophan supplementation in vivo.
Amino Acids
; 49(7): 1169-1175, 2017 07.
Artigo
Inglês
| MEDLINE | ID: mdl-28421297
13.
An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor.
Nature
; 478(7368): 197-203, 2011 Oct 05.
Artigo
Inglês
| MEDLINE | ID: mdl-21976023
14.
Tryptophan-2,3-dioxygenase is regulated by prostaglandin E2 in malignant glioma via a positive signaling loop involving prostaglandin E receptor-4.
J Neurochem
; 136(6): 1142-1154, 2016 Mar.
Artigo
Inglês
| MEDLINE | ID: mdl-26708701
15.
Protein kinase Cß as a therapeutic target stabilizing blood-brain barrier disruption in experimental autoimmune encephalomyelitis.
Proc Natl Acad Sci U S A
; 110(36): 14735-40, 2013 Sep 03.
Artigo
Inglês
| MEDLINE | ID: mdl-23959874
16.
Suppression of TDO-mediated tryptophan catabolism in glioblastoma cells by a steroid-responsive FKBP52-dependent pathway.
Glia
; 63(1): 78-90, 2015 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-25132599
17.
Dynamics of NAD-metabolism: everything but constant.
Biochem Soc Trans
; 43(6): 1127-32, 2015 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-26614649
18.
The complex biology of aryl hydrocarbon receptor activation in cancer and beyond.
Biochem Pharmacol
; 216: 115798, 2023 10.
Artigo
Inglês
| MEDLINE | ID: mdl-37696456
19.
Tryptophan depletion sensitizes the AHR pathway by increasing AHR expression and GCN2/LAT1-mediated kynurenine uptake, and potentiates induction of regulatory T lymphocytes.
J Immunother Cancer
; 11(6)2023 06.
Artigo
Inglês
| MEDLINE | ID: mdl-37344101
20.
Spatial probabilistic mapping of metabolite ensembles in mass spectrometry imaging.
Nat Commun
; 14(1): 1823, 2023 04 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37005414