Detalhe da pesquisa
1.
Alpha-defensins inhibit ERK/STAT3 signaling during monocyte-macrophage differentiation and impede macrophage function.
Respir Res
; 24(1): 309, 2023 Dec 11.
Artigo
Inglês
| MEDLINE | ID: mdl-38082274
2.
Characterization of hepatic inflammatory changes in a C57BL/6J mouse model of alpha1-antitrypsin deficiency.
Am J Physiol Gastrointest Liver Physiol
; 323(6): G594-G608, 2022 12 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36256438
3.
Cigarette smoke exposed airway epithelial cell-derived EVs promote pro-inflammatory macrophage activation in alpha-1 antitrypsin deficiency.
Respir Res
; 23(1): 232, 2022 Sep 06.
Artigo
Inglês
| MEDLINE | ID: mdl-36068572
4.
The Mechanism of Mitochondrial Injury in Alpha-1 Antitrypsin Deficiency Mediated Liver Disease.
Int J Mol Sci
; 22(24)2021 Dec 09.
Artigo
Inglês
| MEDLINE | ID: mdl-34948056
5.
Modulation of calreticulin expression reveals a novel exosome-mediated mechanism of Z variant α1-antitrypsin disposal.
J Biol Chem
; 294(16): 6240-6252, 2019 04 19.
Artigo
Inglês
| MEDLINE | ID: mdl-30833329
6.
Alpha-1 antitrypsin deficient individuals have circulating extracellular vesicles with profibrogenic cargo.
Cell Commun Signal
; 18(1): 140, 2020 09 04.
Artigo
Inglês
| MEDLINE | ID: mdl-32887613
7.
Correction to: Cigarette smoke exposed airway epithelial cells-derived EVs promote pro-inflammatory macrophage activation in alpha-1 antitrypsin deficiency.
Respir Res
; 24(1): 266, 2023 Nov 04.
Artigo
Inglês
| MEDLINE | ID: mdl-37925417
8.
Sirtuin3 promotes the degradation of hepatic Z alpha-1 antitrypsin through lipophagy.
Hepatol Commun
; 8(2)2024 Feb 01.
Artigo
Inglês
| MEDLINE | ID: mdl-38285890
9.
Novel SERPINA1 Alleles Identified through a Large Alpha-1 Antitrypsin Deficiency Screening Program and Review of Known Variants.
Chronic Obstr Pulm Dis
; 10(1): 7-21, 2023 Jan 25.
Artigo
Inglês
| MEDLINE | ID: mdl-36367950
10.
Correlation of alpha-1 antitrypsin levels and exosome associated neutrophil elastase endothelial injury in subjects with SARS-CoV2 infection.
PLoS One
; 17(9): e0274427, 2022.
Artigo
Inglês
| MEDLINE | ID: mdl-36084115
11.
The unfolded protein response to PI*Z alpha-1 antitrypsin in human hepatocellular and murine models.
Hepatol Commun
; 6(9): 2354-2367, 2022 09.
Artigo
Inglês
| MEDLINE | ID: mdl-35621045
12.
Neutrophil elastase promotes macrophage cell adhesion and cytokine production through the integrin-Src kinases pathway.
Sci Rep
; 10(1): 15874, 2020 09 28.
Artigo
Inglês
| MEDLINE | ID: mdl-32981934
13.
Alpha 1 Antitrypsin-Deficient Macrophages Have Impaired Efferocytosis of Apoptotic Neutrophils.
Front Immunol
; 11: 574410, 2020.
Artigo
Inglês
| MEDLINE | ID: mdl-33329539
14.
A Novel Small Molecule Inhibits Intrahepatocellular Accumulation of Z-Variant Alpha 1-Antitrypsin In Vitro and In Vivo.
Cells
; 8(12)2019 12 06.
Artigo
Inglês
| MEDLINE | ID: mdl-31817705
16.
Development, validation and use of ELISA for antibodies to human alpha-1 antitrypsin.
J Immunol Methods
; 388(1-2): 18-24, 2013 Feb 28.
Artigo
Inglês
| MEDLINE | ID: mdl-23195820