Detalhe da pesquisa
1.
Population pharmacokinetics and pharmacodynamics of efmarodocokin alfa (IL-22Fc).
J Pharmacokinet Pharmacodyn
; 51(2): 141-153, 2024 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-37864000
2.
Effects of inhaled JAK inhibitor GDC-4379 on exhaled nitric oxide and peripheral biomarkers of inflammation.
Pulm Pharmacol Ther
; 75: 102133, 2022 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-35644305
3.
Inhaled JAK inhibitor GDC-0214 reduces exhaled nitric oxide in patients with mild asthma: A randomized, controlled, proof-of-activity trial.
J Allergy Clin Immunol
; 148(3): 783-789, 2021 09.
Artigo
Inglês
| MEDLINE | ID: mdl-33744327
4.
Pharmacokinetics and exposure-efficacy relationships of omalizumab in patients with nasal polyps.
Pulm Pharmacol Ther
; 71: 102080, 2021 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34592476
5.
Efficacy and safety of omalizumab in nasal polyposis: 2 randomized phase 3 trials.
J Allergy Clin Immunol
; 146(3): 595-605, 2020 09.
Artigo
Inglês
| MEDLINE | ID: mdl-32524991
6.
A phase I, randomized, observer-blinded, single and multiple ascending-dose study to investigate the safety, pharmacokinetics, and immunogenicity of BITS7201A, a bispecific antibody targeting IL-13 and IL-17, in healthy volunteers.
BMC Pulm Med
; 19(1): 5, 2019 Jan 07.
Artigo
Inglês
| MEDLINE | ID: mdl-30616547
7.
Efficacy and safety of lebrikizumab (an anti-IL-13 monoclonal antibody) in adults with moderate-to-severe atopic dermatitis inadequately controlled by topical corticosteroids: A randomized, placebo-controlled phase II trial (TREBLE).
J Am Acad Dermatol
; 78(5): 863-871.e11, 2018 05.
Artigo
Inglês
| MEDLINE | ID: mdl-29353026
8.
Testosterone supplementation in men: a practical guide for the gynecologist and obstetrician.
Curr Opin Obstet Gynecol
; 27(4): 258-64, 2015 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-26107780
9.
A nontraditional presentation and treatment for emphysematous cystitis.
Urol Case Rep
; 46: 102321, 2023 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-36687746
10.
Population-Based Pharmacodynamic Modeling of Omalizumab in Pediatric Patients with Moderate to Severe Persistent Inadequately Controlled Allergic Asthma.
AAPS J
; 25(4): 56, 2023 06 02.
Artigo
Inglês
| MEDLINE | ID: mdl-37266853
11.
A mechanistic PK/PD model to enable dose selection of the potent anti-tryptase antibody (MTPS9579A) in patients with moderate-to-severe asthma.
Clin Transl Sci
; 16(4): 694-703, 2023 04.
Artigo
Inglês
| MEDLINE | ID: mdl-36755366
12.
Population Pharmacokinetics of Tenecteplase in Patients With Acute Myocardial Infarction and Application to Patients With Acute Ischemic Stroke.
J Clin Pharmacol
; 63(2): 197-209, 2023 02.
Artigo
Inglês
| MEDLINE | ID: mdl-36278839
13.
PK/PD modeling to characterize placebo and treatment effect of omalizumab for chronic spontaneous urticaria.
CPT Pharmacometrics Syst Pharmacol
; 12(6): 795-807, 2023 Jun.
Artigo
Inglês
| MEDLINE | ID: mdl-36896910
14.
First-in-human phase 1 trial evaluating safety, pharmacokinetics, and pharmacodynamics of NLRP3 inflammasome inhibitor, GDC-2394, in healthy volunteers.
Clin Transl Sci
; 16(9): 1653-1666, 2023 09.
Artigo
Inglês
| MEDLINE | ID: mdl-37350225
15.
Phase I and scintigraphy studies to evaluate safety, tolerability, pharmacokinetics, and lung deposition of inhaled GDC-0214 in healthy volunteers.
Clin Transl Sci
; 15(5): 1225-1237, 2022 05.
Artigo
Inglês
| MEDLINE | ID: mdl-35157370
16.
Collapsing FSGS with Concurrent Class 2 and 3 Lupus Nephritis: A Case Report and Review of the Literature.
Case Rep Nephrol Dial
; 11(1): 16-25, 2021.
Artigo
Inglês
| MEDLINE | ID: mdl-33708796
17.
Effect of genetic variation in the organic cation transporter 1 (OCT1) on metformin action.
J Clin Invest
; 117(5): 1422-31, 2007 May.
Artigo
Inglês
| MEDLINE | ID: mdl-17476361
18.
The pharmacogenetics and pharmacogenomics knowledge base: accentuating the knowledge.
Nucleic Acids Res
; 36(Database issue): D913-8, 2008 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-18032438
19.
Genome-wide association studies, field synopses, and the development of the knowledge base on genetic variation and human diseases.
Am J Epidemiol
; 170(3): 269-79, 2009 Aug 01.
Artigo
Inglês
| MEDLINE | ID: mdl-19498075
20.
The Prevalence of Y-chromosome Microdeletions in Oligozoospermic Men: A Systematic Review and Meta-analysis of European and North American Studies.
Eur Urol
; 76(5): 626-636, 2019 11.
Artigo
Inglês
| MEDLINE | ID: mdl-31400948