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Radiother Oncol ; 112(3): 337-42, 2014 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-25005577

RESUMO

BACKGROUND AND PURPOSE: Irradiation of the Pharyngeal Superior Constrictor Muscle (PSCM) seems to play a crucial role in radiation-related swallowing dysfunctions. Purpose of our study was to quantify operator-related variability in the contouring of PSCM on Computed Tomography (CT) scans and adherence with contours derived from MR images. MATERIALS AND METHODS: Three sets of treatment planning CT and their corresponding MR images were selected. Contouring of the PSCM was performed using both a literature-based method, derived from literature review, and an optimized method, derived from Magnetic Resonance (MR) images thus obtaining "literature-based" and "optimized" contours. Each operator contoured the PSCM on CT scans according to both methods for three times in three different days. Inter- and intra-operator variability and adherence to a contour obtained from MR images (named "MR-derived" contour) were analyzed. RESULTS: Thirty-four operators participated and 612 contours were obtained. Both intra- and inter-operator variability and adherence to the "MR-derived" contour were significantly different between the two methods (p⩽0.05). The "optimized" method showed a lower intra- and inter-operator variability and a higher adherence to the "MR-derived" contour. CONCLUSIONS: The "optimized" method ameliorates both operator-related variability and adherence with MR images.


Assuntos
Imageamento por Ressonância Magnética/métodos , Músculos Faríngeos/anatomia & histologia , Radioterapia (Especialidade)/métodos , Tomografia Computadorizada por Raios X/métodos , Análise de Variância , Humanos , Itália , Variações Dependentes do Observador , Guias de Prática Clínica como Assunto , Estudos Prospectivos , Reprodutibilidade dos Testes , Sociedades Médicas
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