Detalhe da pesquisa
1.
Dynamic imaging of nascent RNA reveals general principles of transcription dynamics and stochastic splice site selection.
Cell
; 184(11): 2878-2895.e20, 2021 05 27.
Artigo
Inglês
| MEDLINE | ID: mdl-33979654
2.
Transcriptional Bursting and Co-bursting Regulation by Steroid Hormone Release Pattern and Transcription Factor Mobility.
Mol Cell
; 75(6): 1161-1177.e11, 2019 09 19.
Artigo
Inglês
| MEDLINE | ID: mdl-31421980
3.
The splicing factor U2AF1 contributes to cancer progression through a noncanonical role in translation regulation.
Genes Dev
; 33(9-10): 482-497, 2019 05 01.
Artigo
Inglês
| MEDLINE | ID: mdl-30842218
4.
Single-gene dual-color reporter cell line to analyze RNA synthesis in vivo.
Methods
; 103: 77-85, 2016 07 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27068658
5.
Trigger-helix folding pathway and SI3 mediate catalysis and hairpin-stabilized pausing by Escherichia coli RNA polymerase.
Nucleic Acids Res
; 42(20): 12707-21, 2014 Nov 10.
Artigo
Inglês
| MEDLINE | ID: mdl-25336618
6.
Trigger loop dynamics mediate the balance between the transcriptional fidelity and speed of RNA polymerase II.
Proc Natl Acad Sci U S A
; 109(17): 6555-60, 2012 Apr 24.
Artigo
Inglês
| MEDLINE | ID: mdl-22493230
7.
Complexity of RNA polymerase II elongation dynamics.
Biochim Biophys Acta
; 1819(7): 667-72, 2012 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-22480952
8.
Structural basis for substrate loading in bacterial RNA polymerase.
Nature
; 448(7150): 163-8, 2007 Jul 12.
Artigo
Inglês
| MEDLINE | ID: mdl-17581591
9.
Antisense transcription from lentiviral gene targeting linked to an integrated stress response in colorectal cancer cells.
Mol Ther Nucleic Acids
; 28: 877-891, 2022 Jun 14.
Artigo
Inglês
| MEDLINE | ID: mdl-35694213
10.
RNA transcript 3'-proximal sequence affects translocation bias of RNA polymerase.
Biochemistry
; 50(32): 7002-14, 2011 Aug 16.
Artigo
Inglês
| MEDLINE | ID: mdl-21739957
11.
The transcription factor CBFB suppresses breast cancer through orchestrating translation and transcription.
Nat Commun
; 10(1): 2071, 2019 05 06.
Artigo
Inglês
| MEDLINE | ID: mdl-31061501
12.
Downstream DNA selectively affects a paused conformation of human RNA polymerase II.
J Mol Biol
; 341(2): 429-42, 2004 Aug 06.
Artigo
Inglês
| MEDLINE | ID: mdl-15276834
13.
Kinetic competition during the transcription cycle results in stochastic RNA processing.
Elife
; 32014 Oct 01.
Artigo
Inglês
| MEDLINE | ID: mdl-25271374
14.
Efficient reconstitution of transcription elongation complexes for single-molecule studies of eukaryotic RNA polymerase II.
Transcription
; 3(3): 146-53, 2012.
Artigo
Inglês
| MEDLINE | ID: mdl-22771949
15.
The RPB2 flap loop of human RNA polymerase II is dispensable for transcription initiation and elongation.
Mol Cell Biol
; 31(16): 3312-25, 2011 Aug.
Artigo
Inglês
| MEDLINE | ID: mdl-21670157
16.
Role of the RNA polymerase trigger loop in catalysis and pausing.
Nat Struct Mol Biol
; 17(1): 99-104, 2010 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-19966797
17.
A central role of the RNA polymerase trigger loop in active-site rearrangement during transcriptional pausing.
Mol Cell
; 27(3): 406-19, 2007 Aug 03.
Artigo
Inglês
| MEDLINE | ID: mdl-17679091
18.
Direct versus limited-step reconstitution reveals key features of an RNA hairpin-stabilized paused transcription complex.
J Biol Chem
; 282(26): 19020-8, 2007 Jun 29.
Artigo
Inglês
| MEDLINE | ID: mdl-17502377
19.
A negative elongation factor for human RNA polymerase II inhibits the anti-arrest transcript-cleavage factor TFIIS.
Proc Natl Acad Sci U S A
; 102(42): 15036-41, 2005 Oct 18.
Artigo
Inglês
| MEDLINE | ID: mdl-16214896